Manduca sexta (tobacco hornworm): 115442227
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Entry
115442227 CDS
T07401
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 4
KO
K04428
mitogen-activated protein kinase kinase kinase 4 [EC:
2.7.11.25
]
Organism
msex
Manduca sexta (tobacco hornworm)
Pathway
msex04013
MAPK signaling pathway - fly
msex04624
Toll and Imd signaling pathway
Brite
KEGG Orthology (KO) [BR:
msex00001
]
09130 Environmental Information Processing
09132 Signal transduction
04013 MAPK signaling pathway - fly
115442227
09150 Organismal Systems
09151 Immune system
04624 Toll and Imd signaling pathway
115442227
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
msex01001
]
115442227
Enzymes [BR:
msex01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
115442227
Protein kinases [BR:
msex01001
]
Serine/threonine kinases: STE group
STE11 family
115442227
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MEKK4_N
Pkinase
PK_Tyr_Ser-Thr
Pkinase_fungal
Kinase-like
Kdo
Motif
Other DBs
NCBI-GeneID:
115442227
NCBI-ProteinID:
XP_037297068
LinkDB
All DBs
Position
21:complement(15037131..15103039)
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AA seq
1891 aa
AA seq
DB search
MDGVNLRKKTRIPAMYDSEDSSDDIDTRDVIVRHSRSSSKALLADAGDGAEADLLGTTPP
RSRIRNKEKRNCSSDTRDVIVRHSRSSSKALLADAGDGAEADLLGTTPPRSRIRNKEKRK
NLIDCGMTSYGVGATRTFRERKDPMDFTSPSQMPPVAERLKKRASLKLIRSKERDWKQQD
SSQREIKETPPAAPAVATLVESCSRFMSLTSRPKSVVPDALEAEVEERRPDRDKELPEDR
VNFHNTFCMLINMGNIDRGCKRTISREEKVWQNELKDLIWLELQARCSGRTLAQQDMYLC
SERKLVPALINNIMEYQFVNTNPCQSESKLHFMGHHDDLIDEDKCAAEDQNAGCLEFDCQ
QCSEAIGAAMRDVYSLLEAFNNAVALYPSSKAMMADHPQIATKAFDNRVKTMCLWFNLAL
NMRLKMASMRAMLRALRLKTERSHARTAEMRRYRDHAHATESNLIDCGMTSYGVGATRTF
RERKDQMDFTSPSQTPPVAERLKKRASLKLIRSKERDWKQQDSSQREIKETPPAAPAVAT
LVESCSRFMSLTSRPKSVVPDALEAEVEERRPDRDKELPEDRVNFHNTFCMLINMGNIDR
GCKRTISREEKVWQNELKDLIWLELQARCSGRTLAQQDMYLCSERKLVPALINNIMEYQF
VNTNPCQSESKLHFMGHHDDLIDEDKCAAEDQNAGCLEFDCQQCSEAIGAAMRDVYSLLE
AFNNAVALYPSSKAMMADHPQIATKAFDNRVKTMCLWFNLALNMRLKMASMRAMLRALRL
KTERSHARTAEMRRQPSDPPRECQVRFTTPTDSSGSDLSAQSDVTKEEDKDSDHKEGRDE
DEVDSGVESTRTNEAATTPEIVVSCSASEYSEAEWAESRTHGPACLHGDGFDLGPLHDIT
QLQLLDRCRVSVYREHHREILKTQSVRRCMMFIAKMKKHILSKVHLTLEKPDNLSSDVYS
EDENVVFGDDDENEESLQDESAKEAYELRRYGCWSKEHIAMRLPSYRSHFLLLSSICMEA
VHDYLSFRLETRPENPSCLTVKQLIHELKEGLDISSDMRLEWVRNVEASVADARALQPRH
VRHLRTLLSIFDHTAGDVLKQYLSYLRMMSETEQLARSWLQAEWEFTARLAQRTCSAASL
APQAFTDIACNQLNRVHKSLQKKFEELLDVESVEADSTSRHTVFAACRLAQSIYAGEREA
ALQAAQWARALAARLARLAAHAPHAPHAHLAMRQQIFESLMTVRDFVVKNVHEILKKSDA
PVTDEYFKELDESVSGRVRELLLQVFKVGFELDKELYKYVRAPFSAYEERESRRRRPASL
QPPRPPPVSRRRRPDTVLLHESFNPMIHKELQRFVNDAPLSRPSVTTNATRSHWAKLIRS
ESVVEENEVNVFDALNNFGENQTQSRIEALLVGVRAPAPADSHASAGDARVSGEERQWAA
RVARAVIEFARCWMDFVVRRCDRGRGTRPRWASQGLEFLTLACDPCNTKHLSEEEFKELK
QLMDGCISHVIGSRPPPAKSPEGPAPSPRPRHRLHSPLPSSSSLKDVSTPPTPPGEREPS
LVFLERDPSSYQRRVLSAVTRIEQRRERQLVENKRVGRVLEPAVTPYEPKLRQLTFKWQR
GLKIGAGAFGKVYTVVNTESGQLLAMKELSVGAGDRRALQRAANELRVLEGVVHPHLVRY
YGCELHREELLLFMELCVEGSLEALVCASGALPEPAARRYTKQLVSALHALHARNIAHRD
VKSGNIFLTNDGHCLKLGDFGCAVKIRANTTAPHELQGFVGTQAYMAPEVFMKNSHGRAA
DIWSLGCVVTEMASGKRPFPEYDNYQIMFKVGMGGRPEIPDTLSEEGQQFCESCLTHESD
QRPTAAALSLHSFLMVKSDDDCQCDPGHLIS
NT seq
5676 nt
NT seq
+upstream
nt +downstream
nt
atggacggtgttaatttgaggaagaagacgcggattccggcaatgtacgactcagaagat
agttctgatgacatcgacacccgggacgttatcgttcgtcacagccggtcttcgtcgaag
gcgctgctagcggacgcgggcgatggcgccgaggcggacctgctcggcaccacgccgcca
cgctccaggatcaggaacaaggagaaaaggaactgttccagcgacacccgggacgttatc
gttcgtcacagccggtcttcgtcgaaggcgctgctagcggacgcgggcgatggcgccgag
gcggacctgctcggcaccacgccgccacgctccaggatcaggaacaaggagaaaaggaaa
aacctgatagattgtggtatgacgagctacggcgtcggagccacgaggacgtttcgggag
aggaaggacccaatggacttcacgtcgccttcccagatgcctccagtggcagagcgtctg
aagaaaagggccagcttgaagctgatacggtccaaggaacgagactggaagcagcaggac
tccagccagcgcgagataaaggaaaccccacctgctgcaccagccgtggctactctggtt
gaatcatgcagccggttcatgtcgctcacatcccggccgaaatctgtggtcccggatgcg
ctggaggcggaggtggaagagcgaagaccggaccgggacaaggagctgcccgaggaccgc
gtcaacttccacaacaccttctgcatgctcatcaacatgggcaatatcgacagagggtgt
aagaggactatcagccgagaagagaaggtttggcagaatgagctcaaagaccttatctgg
ctggagctgcaggctcgatgttcaggcaggaccctggcccagcaggacatgtacctgtgc
agcgagaggaagctggtgccggcgctcatcaacaatattatggaataccaattcgtgaac
acaaacccttgtcaaagtgaatcaaaactgcacttcatgggacaccatgacgatcttatt
gatgaagacaaatgtgcagctgaagaccaaaacgcgggctgcctggagttcgactgccag
cagtgctcggaggcgatcggcgccgcgatgcgcgacgtgtactcgctgctcgaggccttc
aacaacgccgtcgcgctctacccctccagcaaggccatgatggccgaccacccgcagatc
gccaccaaggccttcgacaatagggttaagacgatgtgcctgtggttcaacctggcgctc
aacatgcgcctgaagatggcgtcgatgcgcgccatgttgcgcgcgctgcggctcaagacg
gagcgcagccacgcgcggactgccgaaatgcgcaggtaccgagaccatgcacacgctacg
gaatcaaacctgatagattgtggtatgacgagctacggcgtcggagccacgaggacgttt
cgggagaggaaggaccaaatggacttcacgtcgccttcccagacgcctccagtggcagag
cgtctgaagaaaagggccagcttgaagctgatacggtccaaggagcgagactggaagcag
caggactccagccagcgcgagataaaggaaaccccacctgctgcaccagccgtggctact
ctggttgaatcatgcagccggttcatgtcgctcacatcccggccgaaatccgtggtcccg
gatgcgctggaggcggaggtggaagagcgaagaccggaccgggacaaggagctgcccgag
gaccgcgtcaacttccacaacaccttctgcatgctcatcaacatgggcaatatcgacaga
gggtgtaagaggactatcagccgagaagagaaggtttggcagaatgagctcaaagacctt
atctggctggagctgcaggctcgatgttcaggcaggaccctggcccagcaggacatgtac
ctgtgcagcgagaggaagctggtgccggcgctcatcaacaatattatggaataccaattc
gtgaacacaaacccttgtcaaagtgaatcaaaactgcacttcatgggacaccatgacgat
cttattgatgaagacaaatgtgcagctgaagaccaaaacgcgggctgcctggagttcgac
tgccagcagtgctcggaggcgatcggcgccgcgatgcgcgacgtgtactcgctgctcgag
gccttcaacaacgccgtcgcgctctacccctccagcaaggccatgatggccgaccacccg
cagatcgccaccaaggccttcgacaatagggttaagacgatgtgcctgtggttcaacctg
gcgctcaacatgcgcctgaagatggcgtcgatgcgcgccatgttgcgcgcgctgcggctc
aagacggagcgcagccacgcgcggactgccgaaatgcgcaggcaaccatccgacccccct
cgagagtgccaagtgcggttcacgactcccacggactcgagcggaagtgacctcagcgcc
cagtccgacgtcactaaggaggaagacaaggacagtgaccacaaggagggacgggacgag
gatgaagtcgatagcggggttgagagcactaggacgaacgaggccgccacgacgcccgag
atcgtggtgtcgtgcagcgcgtcggagtacagcgaggcggagtgggcggagtcgcgcacg
cacgggccggcgtgcctgcacggcgacgggttcgacctggggccgctgcacgacatcacg
cagctgcaactgctggaccgctgccgcgtctccgtatacagagaacaccatcgtgagatc
ttgaagacgcaaagcgtgcgtcgttgcatgatgttcatcgccaaaatgaagaaacacatc
ctgagcaaagtccatctcactctggagaaaccagataacttgagcagcgacgtgtattct
gaagacgaaaatgtagtattcggtgatgatgacgagaacgaagagtcgctgcaggacgag
agcgcaaaagaagcatatgaattgaggcggtatgggtgctggtccaaagaacacattgcc
atgaggttgccgtcctatcgatctcactttctgctgctgagcagcatctgcatggaggcc
gtccacgactacctttcatttaggctggaaacgcggccggagaatccgtcctgtttaact
gttaaacagttgatccacgagctgaaggagggtctggacatctcgtcggacatgcggctg
gagtgggtgcgcaacgtggaggccagcgtggccgacgcgcgcgcgctgcagccgcgccac
gtgcgccatctgcgcacgctgctcagcattttcgaccacaccgccggcgacgtgctcaag
caatacctgtcgtacctgcggatgatgtcggagacggagcagctggcgcggtcgtggctg
caggcggagtgggagttcacggcgcgcctggcgcagcgcacgtgcagcgccgccagcctc
gcgccgcaagccttcacggacatagcgtgtaaccagctcaacagggtacacaaatcactc
caaaaaaaattcgaagagttattggacgttgagagcgtggaggccgacagcaccagcaga
cacacggtgttcgcggcgtgccggctggcgcagagcatctacgcgggcgagcgcgaggcg
gcgctgcaggcggcgcagtgggcgcgcgcgctcgccgcccgcctcgcgcgcctcgccgcg
cacgcgccacacgccccgcacgcacacctcgccatgaggcaacagatcttcgagagcctg
atgacagttcgtgacttcgtagtaaagaacgtgcacgagatcctgaagaaaagcgacgcg
cccgtgacggacgaatacttcaaagagttggacgagagcgtcagcgggcgcgtgcgcgag
ctgctgctgcaggtgttcaaggtcggcttcgagctggacaaagagctgtacaagtatgtg
cgcgcgccgttcagtgcgtacgaggagcgcgagtcgcggcggcgccggcccgcgtcgctg
cagccgccgcgcccgccgcccgtgtcgcgccgccgccgccccgacaccgtgctgctgcac
gaatccttcaaccccatgatccacaaagagctgcagaggttcgtgaacgacgcacctctc
agccgaccctcggtgaccaccaacgccactcgtagccactgggccaagctcattcggtca
gagagcgtggtggaggagaatgaagtcaatgtattcgacgcactcaataacttcggagaa
aatcagactcagtcccgcatagaggcgctgctggtgggcgtgcgcgcgcccgcgccggcc
gactcccacgcgagcgccggcgacgcgcgcgtgtcgggcgaggagcggcagtgggcggcg
cgggtggcgcgcgccgtcatcgagttcgcgcgctgttggatggacttcgtggtgcggcgc
tgcgaccggggcaggggcacgcggcccagatgggcgagtcaaggcctagagttcctaacg
ttggcctgcgacccctgcaacactaagcatctaagcgaagaggaatttaaggaattaaaa
cagctgatggacggatgcatctcccacgtgattgggtcgagacctccgcccgccaaatct
ccagaaggaccagcaccttcgccacgacctcgacaccgtctacatagtcccctgccatcg
tcctcgtcacttaaagacgtgagtacgcccccaacaccgcctggagaacgggaaccttcg
ctcgtcttcctagagagagatccgtcctcgtaccagcgtcgcgtgttgtcggccgtgacg
cgtatagagcagcgccgcgagcggcaactagtcgagaacaagcgcgtgggccgcgtgctg
gagcccgccgtcactccctacgagcccaaactcaggcagctcaccttcaagtggcagcgt
gggctcaaaatcggtgctggagcctttggcaaggtatacacggtggtgaacacggagagc
ggccagctgctcgcgatgaaggagctgagcgtgggcgcgggcgaccggcgagcgctgcag
cgcgccgccaacgagctgcgcgtgctcgagggcgtcgtgcacccgcacctcgtgcgctac
tacggctgcgagctgcaccgggaggagctgctgctgttcatggagctgtgcgtggagggc
tcgctggaggcgctggtgtgcgcgtcgggcgcgctgccggagccggcggcgcggcgctac
accaagcagctcgtgtcggcgctgcacgcgctgcacgcgcgcaacatcgcgcaccgggac
gtcaagagcggcaacatcttcctcacgaacgacggacactgcctcaagctgggtgacttc
ggatgcgccgtcaaaatccgcgccaacaccaccgcgccgcacgaactacaaggattcgtc
ggcacgcaagcgtacatggcgccggaggtgttcatgaagaacagtcacggacgcgccgcc
gacatctggtcgctcggatgtgtcgtcactgagatggcttccggaaagcgcccattcccg
gagtacgacaactaccagataatgttcaaggtgggcatgggaggacggcccgagataccc
gacacgctctccgaggagggacagcagttctgcgagagttgtctcacgcacgagtccgac
cagcggcccaccgctgccgctttgagtcttcactcattcctaatggtaaagtcggacgac
gactgccagtgcgacccgggacacctgatctcgtaa
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