Manduca sexta (tobacco hornworm): 115444232 Help Entry 115444232         CDS       T07401                                  Name (RefSeq) midasin   KO K14572   midasin Organism msex  Manduca sexta (tobacco hornworm) Pathway msex03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:msex00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     115444232  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:msex03009]     115444232 Ribosome biogenesis [BR:msex03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     115444232 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA_3 AAA AAA_7 AAA_16 AAA_22 Sigma54_activat AAA_18 AAA_6 AAA_14 nSTAND3 TsaE Sigma54_activ_2 bpMoxR Dynein_heavy ABC_tran RsgA_GTPase DUF815 IstB_IS21 MDN1_4th Mg_chelatase PduV-EutP VWA_2 VWA Zeta_toxin VWA_CoxE SRP54 cobW IPT Motif Other DBs NCBI-GeneID:  115444232 NCBI-ProteinID:  XP_030025783 LinkDB All DBs Position 16:7932514..7962140 Genome browser AA seq 5374 aa AA seqDB search MAVNDTHVALKTIAAITNTSELAKTCRELQKSEPKDIINKLSDFILNVEDALLFKQHLSN ILLALVSTRIPLKLVFSNPQFDICSDSEKISHLEYSIVLAALSDHPDVLQYALKYFDINK VPPFEVFIHHEDSYNVAPKKRRLLDSRQKITDKQIVTCCYKLLTKLPNELSGKWDWTNFV SNFCNHENADIKWMVKECMVILTNMTEAQSKSLSRNLNISELESLHCANAQKQETVYPIS DYIKDVDLNVDSVVNVDGILLPIHDKNNVQDGNLVPVKSTINNLRSLALAVASGQALCLM GPVGSGKTSLVEHLAAITGRKGMAFKKVQLGDQTDSRMLLGSHQCTDVPGEFVWRPGVLT EAVQNGHWLLLEDIDCAALDVASTLSSLLERNSLCVPGYRDSLPVTPGFQLFVTQRTLTT NYGFQKKMSNSSALLQKHLTQINVEPLSRSELSEIVQTLHPSLSTICSRMIEVFMMFSVG SHDTSLQTTDAVTDKETSINVLRGSRLISTRDLMKWCARAVVGFDVTSPEAALKVLQDAL DIFTCSVSSPEHRLELAKKVGTCLGIVETKSEFYCKHYKPNVSLHPACLEVGRAKVPRVE KSLDSIDFDAKQVVFSFTRQSACLLERIACCVTSNEPVLLVGETGTGKTSSVQYLARQTG HKLVVINMNQQSDSADLLGGYKPVDLKYVIRPIRNEFEELFRSFYNIEKNKKFLSHIETC YETENWTALLTLMKQSHKAALSRLTAEKKEKKLKKWITFGYKLSKLDQQVKAASKLTFAF IEGSLVKAMQEGHWVLLDEINLASAEILECLAGLLEDKNESIDLLEKGDKVPIKRHPDFT LFACMNPATDVGKKDLPVGLRNRFTEFFIDELMERNDLMLLIGDYLYHMNLSGAVLEAIY SFYSNIRKEAKLNLVDGAGNSPHYSLRTLCRALTAAAKAKCGTVARSLFESFCLSFLTQL DSSSHPIVEAMIAKAVIGKKNIKTVTNQAIPEPQVLGQKFLLFEGHWIPQGKEDVVIPEG YILTPTVRKNLRDIARIISLGRLPVLIQGDTSVGKTSLITYIAKTSGNYCVRINNHEHTD LQEYIGSYAADANGKLVFKEGVLVEAMRKGYWIILDELNLAPSDVLEALNRVLDDNRELF IPETQQVVKADPNFMLFATQNPPGLYGGRKMLSRAFRNRFVELHFDEIPKKELETILHQR CHVPPAYSKKMIAVMADLQLRRRGSAAVQGKDGFITLRDLFRWGERYKHASKEALTGEKF YDWDQHIADEGYLILAGKVRQPEERSIIVEIIQKNIKRTVNPDNLFNLNEETSPVTKTIL ETILNNQFDEFAHIVWTYNMRRLAILIAKAFTFKEPVLLVGETGCGKTTICQVLAALKKR QLLAVNCHMHTESSDFLGGLRPVRQYKNDGRLFEWVDGPLVKAMESGDMFLADEISLADD SVLERLNSLLEPERQLVLSERGMEDNSDIVVVTANENFHFIGTMNPGGDFGKKELSPALR NRFTEIWCDSVTTREDLQKVLEKSVNKGISLGNQEDGSSGIGTSILDFTDWLKNSEATSK FPFSIRDLLSWVQFINITVAKGLLDIPEAYVHGACMTFLDCFGTALTGHIDSEVLTTLRK TAIDFLLNQIKTVGSEYLDNLRDMLSNKQTKFIAESDDGKFGIKPFYVDVGPNKDIVEGS ENFTFTAPTTGANTLRLLRGMQLNKAILLEGNPGVGKTSLVTALAKSSGHKVVRINLSDQ TDITDLFGTDLPAEDGSFTFKEGAFLSALQKGDWILLDELNLAPQPVLEGLNACLDHRGE VFIPELGKTFKIKQETKLFACQNPLKQGGARRGLPLSFLNRFTQVYVDTLTHEDLIYIVN AQYPKIPQDILHRIVKFNCKVAYEIVELQSWAHRGSPWEMNLRDIQRWCEAILNDIDRGK KVAPGKFVDMLYVNRMRTFKDKERMIQEYNEVFEPDYPRSDSAPQFYINDKNIEIGDVIL ERNYEKYFKNRRALESNLVVLRNQMPTLKALAQSVKMNWLTILVGPSATGKSSIVQVLAD LTGNDLQVIPVTSAMDVSDLLGGFEQVDYNRNLENIFDKLETISIQTVRDMWLNEKHEHW KSNKILSHLYQYKTLQTTTDNVNNDVEIFKERMNFLLNHCGKLEEYTKPYSFVANTLKDI VISLKKLETKISNVTSVNIGGKFEWVDSLLVKTLIEGSWLLLDNVNLTSAAVLDRLNGLL EPNGVLSIPERGNLSEIKPHPNFRVFFTMDPKYGEISRAMRNRGVEIFLLRSDDWNTVLS TTMAHMDLTGLLASCGLPTEYHEICIEAHERMTAFIQGLDRPTISHLLQAAHLTWQQIVR GMTMYTAVINSFTDVYIKPRCGGDFATDMNLSLAEIKNYMMKRLEDLLQEVDFVEPRSVS HTLTVKGLCSSSSHEVAKQISYVACQEFLGLQDLSKCHLQVLFSMLTAYLKCPKELCAIT HSIIKERLMEKYTDKIAIITEYNDKILEFFERNADVEVLFKRFYPESFDLNDGELKGSNK AMLLLYNELTKIHLQTYINKSCFSTQDYSIAVLAGKMTDDFIEYPILKQCFAYLKIIEAY IKTAISKDKDSLDDNATCKILQFLNWRNRLVKLSLEPMFTMTETRKRQILREDIVPLLYI HSKWVHKYLVEELFYLSRDSNDITEFEDAVKIIELNRDENNSKIAKLSKKLRKLYGQPKL YVNEQEYDLCTARRNVYNKLTVNMNQPLKNQLNILLASANTETDISFALDVPDGDKLALV QENITKLNKMPKEFRTTGLETKLLPITSYIIQRVIKMLQSKFFVTINRLNVKEDMISSDV SDILINLVHLGKNTKGFPPALLNLLQVVQRIQAKDQELLSQRISSVPSKFWDEFYKFLIN SPALYPMPFLTINKMDSEEPEDLPVNSKRVSDNLPLLPYYVQKLTITENNQDARHLLAYE TISLEERSEYSIQLGTILNILWKNIATLDTAANCKLQTDAAFEIQKFEELMLYLGSILNT SKENNDVSIEEIKLKLQQHLKDDSILNTLLKTPVYEELKRSQNDKIKVKLLTSHLSLLTS VLSLVFLSEINPVDHVEKYRLKLQYIEEDIKMFDALLSTYYMHGLVTGTLSITKEILKSS QVPVTEFCAKETKDDLKRVHPYCSHILELKESTAQRVQKYALGNTFRPQEPSYGSFVKDC KHFAKSVLSPQAMKGITGNLIGICYKLYEHLQAMSTEKGLVENARTIVKETSSWLYSVNA FYRKLESSYSDAFPDLAKPLQTAISQIVYSVSSLRDLVIEMSQKKEQGLVLSKAVTDLMV YPNVINMRGDKEEHLNRFIHSDFVALLNRNVLASDDFNAAEQQFIEVLKMNLLELRMHCT AADRIDKMSADSMVTMLNAIVKAWDLQQREIEKKKQDDEALYVTKSKCEDEDEEAIAYEE ILEMFPSYSEVDFGDFKPPTLEQKIKPKLEQKTKPKQFISSEDVSLVYKWHSSFVRNMTE AEWLPSRKKLVGNDIISAFLQRYPVFSRIIQNAWDALDAELEGSISPSLLVLVSQIKEKV DGQDSSSSKADFYHSPWISETKQCLPLLQRVKESTNELLDQWPDFPTLKEIIVIVNRILS FPVTSPVSRFLTGLELLRDKIEEWNRNAHKGNNLIDISLAVGQQIINWRKLEMGHWKECL SNLYYRKQSEAHKYWFYLYAVINTYLDSESPDTVPAERVISVLRDFMEKSNLAEYEVRLD IIYVYHCHLVHLEASDRRDELLAILWNTYNYYSQFSAQVAAHIKEKRAPIEKKLRDFVKI CTWDRDLSYWSVKDTVEKAHKALHKHTKEFESVLKESVASCLVDSSWEASAEHVGIWDRP KRATTAAPAGGAYMIDPQNHVVLARNIKKYLDHAEQPCEYITDGSLLSKVPSLLNKAKTL CKDTITNTSYPSLVQELDDFVTLVIETSTHLGSLEVDAALPREKQKSQAKNIVQQKRKAL ADLFKYLSKLGLNYRTGLVILSASDKELYDFTLPPVDLGAAIGYLKSRRCDATLGLLWTG CETYFQKNIARHRLLTAALQSPHQDLGMQNIERCKGFAAQLLNLTNKQKRSISKYSRLLS DLRTVATNLTNALDIDTAKTNLPTLKQKIDILIECYANTSILLEQFNMVLKSCPEKGVGA DYEPDFDSVLSDSKIVRCYKNSDEWRELCRKVKALIANVSKQKNNLHKVVYTTPKQIGQH VGELPLASQSHIDVANDCEENLEKLTRDVDDLLEEYQFRLKSQLCEHVPQHPILRSMVEL SQYLKDTVNQLGELNKDSDVPMDSITSDDLINQTEDLIATMLLIVQSVYKRHLPINENME VINAIDEIIQSQDKPESRDILEDKHLKERLHDKLSNDSKMLQLDSLINKTYNVLINYVQY VAKGSKDIDEVKNVVMRSIPILEQIVLFVQYFISQKVAVHRVSCKMLSVLLKIFSDLASK GFCKPSDLDMEEGEGEGGPGKLSGGTGLGEGEGQKDVSERIENQDQLDDAHRPGEEKKEE DRDCKEEEKGINMTDDFDSHLQDVEKKEGDDSEQEDDEDDADKQMGDTDNAAERLDQQIW GSEDEEDIDESNEGKKDKEEKGKGESTGEKEMGAKEEEEQGTDDGAEGKDKKKKKDINEM NEPEVDDDHVDPYHGNQQQLPEPEDFEMPDNMNMDGEEGADDNEGETETENPFDIDVMKE NISEEQEDKDDGKGEEKEDNKHGMEVSSDEEGGDDGKDDANDGQNDEENKKEDEEPGKDE HEDDGDGEIENEANVEDKPENTENTDNPEVPDKEDLQKNPEKINEEDEVEEKGQDANPQA NPSTNDPTAEDKAENAEMERGTDDNVDTNAEQMKDEDAAPFEQSQEQVGEEKRSTGRSEL DKSDKGHKGDKQAASKTERSQEKRKRHENKPGQTDHERTLGDVNEKKNKQMKTLNVERED ENADEGGDADDDAEREADAFQHVKQAKKDDLQAIDAATKEQADQQPILQKDEEEDADKLK EDEDVAMDVDDDELEIEKSEELKSEKMKDGAQKEQEKSGNKNEAGEEPTGETGVEVEGEK VVTSHVPRGTDTTYHTRLDETQIQTEDMTMEEYMGIREWLTSGPTHGQGSVGVWRTLWRD AAGAARALCERLRLVLEPTGRSRRAGDFRTGRAINMRRVIPYIASHFRKDRIWLRRTKPA KREYKIAIAVDDSSSMSDNRSKELAFESLALVSQALNLLESGDLAVISFGEKPNLLHPFT EQFSEHSGSKILEQLRFEQTKTKIAQLLDFCTVLFEEQTVRSDAVNAKLLVVVSDGRGIF SEGETRVMHAVRRARQQGIFLVYVIIDNPDNKDSIMDIRRPIIDPATNSFVRFESYLDSF PFPFYLILRDMSALPTVLGDALRQWFELAANTAS NT seq 16125 nt NT seq  +upstreamnt  +downstreamnt atggcagttaacgatacgcatgtagctcttaaaacaatagcagccataacaaatacttcg gaacttgctaaaacgtgtcgggaactccagaaatcggaacctaaagatataattaataaa ttatctgatttcattttaaacgtagaagatgcattattattcaagcagcatttatcaaac atcctcctcgcattggtatcaacaaggatacctttgaaactagtattttcaaatcctcag tttgatatatgcagtgattctgagaaaataagtcacttggaatattctatagttctagct gcattgagtgatcatcctgatgtattacaatacgctcttaaatattttgacatcaacaaa gtgcctccatttgaagtgtttatacatcatgaggattcctacaatgtggctccaaagaaa aggcggctacttgacagtagacagaagattacagataaacagatagtgacatgctgctat aaattgcttacaaagttgcccaatgaactgtcagggaaatgggattggacaaattttgtt agtaacttttgtaatcatgagaatgcagacatcaaatggatggtaaaagaatgtatggtg atattaaccaatatgactgaagctcaatcaaagagtttatcaagaaatctcaacatatcg gaattggaatcattgcattgcgcaaatgcccagaaacaagagacagtttaccctatcagt gactatataaaggatgtggatttaaatgtggattctgttgtgaatgttgatggcatttta ttacctatacatgacaaaaacaatgtccaagatgggaatctcgttcctgtgaaatctaca ataaacaatttgaggagcttagcccttgctgtggcatcaggacaagctctttgcttaatg ggtccggtaggatctgggaagacctctcttgtagaacatttggcagcgatcacaggacgc aaagggatggcgtttaagaaagtacaacttggcgatcagactgactcacgcatgctgctc ggctcgcatcagtgtaccgatgtcccgggagaatttgtatggagacctggtgttttaact gaagccgtacaaaatggtcattggttactattggaggatatagactgtgctgcgctggat gtcgcgtcaactctaagttcattattagaacggaattctttatgcgtcccaggatatagg gactcgcttccagttactcctggctttcaactctttgtcacccaaagaacactcacaacc aactatggtttccagaagaaaatgtccaattccagtgccctactgcagaagcatttaaca caaatcaatgtggaaccgctatcaagatctgaactatcggaaatagtacagacactgcat ccaagtctttcaacaatatgctcaaggatgattgaagttttcatgatgttttctgtcgga agccatgacacatccttacaaactactgatgcagttactgacaaggaaactagtataaat gtgttgcgtggttctagactaatctcaacaagagatttgatgaagtggtgtgcgagggcg gtcgtgggttttgacgtcacgagccctgaggctgcattaaaagtccttcaagatgcacta gacatattcacttgttctgtatcatctccggaacacaggcttgagttggcgaaaaaagtc ggcacatgtttaggaatagttgaaacgaaatcagagttctattgtaagcattataaaccg aatgtatcattgcatccagcttgtttagaagttggtagagcaaaagtgccgcgcgttgaa aagagcttagattcaatcgactttgatgcaaaacaagtcgtgttttcttttacgcgtcaa tcagcttgcttgttggagaggatagcttgctgtgtcacatcaaatgagcccgtgctgctt gtaggagaaactggtacagggaagacgtcatcagtccagtacttagctagacaaacaggc cataaacttgtagttatcaacatgaaccaacaatccgattctgctgacttactcggcggt tacaaaccagtcgacttgaaatatgtcatacggccaatacggaacgaattcgaagaacta ttccgtagtttctacaacattgaaaagaataagaagtttctcagtcatatagaaacgtgt tatgagacagaaaattggacagcgttactgacattgatgaagcaaagtcataaagctgcc ctgagcagattgactgctgagaaaaaggagaagaaattaaagaagtggatcacattcggt tataaactatcgaaattggaccaacaagtgaaagccgcgtcgaaactgactttcgctttt atcgagggttccttagtcaaagctatgcaagagggacattgggtgttactagacgaaata aatttagcctcagccgaaatattggaatgtctggctggtttattagaagacaaaaacgag tcgatagatttattagaaaaaggtgacaaagttcctatcaaacggcatccggattttact ttattcgcttgtatgaaccctgctacagatgtagggaagaaagatctaccagtaggtctc agaaatcggttcacagaatttttcattgatgaattaatggaacgcaatgacttgatgctt ctcataggtgattacttatatcatatgaaccttagtggcgccgttttggaagcaatttac agtttctattctaacataaggaaagaagcaaaactcaatcttgttgatggtgcaggaaat tcgcctcattattccctgagaactctgtgcagagctttaacagcagcggccaaagcgaaa tgtggtacagtggcgaggtcactcttcgaatcgttttgtttatcgttcctcacgcaattg gatagctcatcgcatccaatcgtcgaagctatgattgccaaggcagttatcgggaagaag aatataaagacagtcaccaatcaagcaatccctgaaccgcaagttctcggacaaaagttt ttattgtttgaaggccattggatccctcaaggcaaggaagatgtagttatacctgaggga tatattcttacacctacagttagaaagaaccttcgagatattgcgagaattatatctctt ggacgactaccagttttaatacaaggtgacacgtcagtagggaaaacatctctaatcact tacatagcaaaaacatcagggaattactgcgtcagaatcaacaatcacgaacatactgat cttcaagaatacataggatcgtatgccgctgatgctaacggcaaactggttttcaaagaa ggtgttcttgtcgaagcaatgaggaaaggctattggatcatactcgacgaattgaattta gcacccagtgacgttttagaagccctgaatcgagtactagatgataatagagaactgttc atacctgaaacacagcaggttgtaaaagccgatccaaactttatgctttttgctactcaa aacccgcctggattgtatggaggacgtaaaatgttgtccagagcgtttagaaatcgtttc gtcgaattacactttgatgaaataccgaagaaggaattggagacgattttacatcaaaga tgccacgtgccgccggcgtacagcaagaaaatgatagctgtgatggcagatttgcagctg agacggcgtggttctgccgcagtccaaggcaaagatggatttattactctgagggatttg ttcagatggggtgaaagatataaacatgcttccaaagaggctctaacgggtgaaaaattc tatgactgggaccagcacatagctgatgaaggctacctaattttagcaggtaaagtgagg caacccgaggaaaggagcataatcgtagaaataatacaaaaaaatataaagaggacagtg aatccagataatctttttaacttaaacgaggaaacatctccagtgactaaaacaatacta gaaacaatcttgaacaaccaattcgatgaatttgcgcatatcgtatggacatataatatg aggcgtttggcaattttgatagccaaagcgtttacttttaaagaaccggtattgcttgtg ggcgagactggctgtggtaaaacaacaatatgtcaagttctcgctgcattgaaaaagcgg caacttttagcagtcaattgtcacatgcacacagagagctccgactttttaggcggactg agacccgtgcgacagtacaaaaacgacggcagattatttgaatgggttgatggaccctta gtgaaagctatggaatctggagatatgtttctggctgacgagatatctttagctgatgac agtgtgttagaaagattgaattctttgctagaacctgaaagacagttggtactcagtgag agaggcatggaggacaattctgatatagttgtcgtaacagctaacgagaacttccatttt atcggaactatgaaccctggcggtgactttggtaagaaagaactttcacccgctttgcgt aacagattcacagaaatatggtgtgacagtgtcacaactagagaagatttacaaaaagta ttagaaaagagtgttaacaaaggaatctcattaggaaaccaagaagatggtagttctggt ataggaacaagtattttggacttcacagactggcttaagaattcggaagcgacgagcaaa tttccgtttagtattcgcgatttgttatcttgggttcaattcattaatataactgtggca aaaggcctcttagatatccctgaagcttacgtccacggtgcgtgcatgactttcttagat tgttttggcactgccctaacaggacatatagattccgaagttctgaccacactacgaaaa acggccattgattttttgctcaatcaaattaaaacagtaggaagtgaatatttagataat ttaagggatatgcttagtaacaagcaaacaaaattcattgctgaaagtgatgatggtaaa tttggcattaagccattttatgttgatgtgggaccaaataaggatatagtagaaggaagt gagaatttcacatttacggcccccacaacaggtgctaatacactgcgattgttacgggga atgcagttaaataaagctattttgcttgaaggcaaccctggggtggggaagacaagctta gtgacagcgttagcaaaatcatcaggacataaagtcgttagaatcaacttgagcgatcaa actgacataactgacctttttggcacagacctccctgcagaagacggttcgtttactttc aaagaaggtgcgtttttgagtgctttacaaaaaggagattggattcttttggatgaactt aatttagctccccagcccgtcttggaaggtctaaatgcttgtttagatcaccggggtgaa gtgtttataccagaattaggaaaaacatttaaaataaaacaagaaacgaaattgttcgcc tgccaaaatcctttaaagcaaggcggggcgcgaagaggccttccactttcgttcctcaac aggtttacacaagtctatgtagatactttaacacatgaagatcttatttacatagttaat gcacagtatcctaaaatacctcaagacatattacacagaatagtgaaatttaattgtaaa gttgcgtacgaaatagtagaattacaatcgtgggctcataggggatcgccctgggaaatg aatttaagagatatacagcgatggtgtgaagctatactgaatgatatagatagaggtaaa aaagttgcacctggaaaattcgttgatatgctttacgtgaatcgtatgagaacttttaaa gacaaagaaagaatgattcaagaatacaatgaagttttcgaaccggactatccgaggagt gacagcgctccacaattttatattaatgataaaaatattgaaattggtgatgtaattttg gaaaggaattacgaaaaatatttcaaaaaccgtcgtgcgctcgaaagtaatttggtagtt ttgagaaaccaaatgcctacattaaaagctttggcacaaagtgttaaaatgaattggttg actatactcgttggtccttctgctacggggaaaagtagtattgtccaagtactagccgac ttgaccggcaatgacttgcaagtcattcctgtaacatcggcaatggatgtgtcggattta ttaggtggttttgaacaagtcgattataacaggaatctcgagaacatttttgataaactg gaaacaatttcaattcagacagtaagagatatgtggctaaatgagaaacatgaacattgg aagtcgaataaaattcttagtcacctgtaccagtacaagactttgcaaaccactacagat aatgttaacaatgatgtagaaatctttaaggaaaggatgaatttccttttaaaccattgt ggtaaattagaagaatatactaaaccgtacagtttcgttgcaaatacattaaaagatatt gtgatcagtttgaaaaaattagaaacaaagatatcaaatgttacgtcagtgaatattgga gggaaatttgaatgggttgactcattgctagtcaaaacgttgatagaggggtcttggtta cttctggataacgttaatttgacgtcggcagcagtgttggatagactaaatggtttatta gaacctaatggtgttttaagtattcctgaaagaggcaatttgagtgaaattaaaccgcat ccaaactttagagtattctttactatggacccgaagtatggagaaatttctagagcgatg aggaatcgtggtgtagaaatattcctcctgaggtctgatgattggaatacagtgttatca acaacaatggcgcacatggatttaactggattgctggcgtcttgcggtttgccaactgaa tatcatgaaatttgcatcgaagctcatgagaggatgactgcatttattcaaggtctcgat cgtccaacaatatcgcatttacttcaagctgctcacttaacatggcagcaaatcgtacga ggcatgacaatgtatactgcggtgatcaatagcttcacagacgtgtatataaaacctaga tgcggtggtgactttgcgactgacatgaacttatctttggctgaaataaaaaattacatg atgaaacgtttggaagatttgttacaagaagtcgatttcgtagagccacgaagtgttagc catacattaaccgtcaaagggctatgttcaagctcatctcacgaagtcgcgaagcaaatt tcatacgtcgcgtgtcaagaatttttgggtttacaagatttatctaagtgccatctgcag gtgttatttagtatgttgacagcataccttaaatgccccaaagagctttgtgctataaca cacagcattatcaaagagcgtttaatggaaaagtacaccgataaaattgctattatcact gaatataatgacaaaattcttgaattttttgaaaggaatgctgatgttgaagtgttgttt aaaagattctaccctgaaagttttgatttaaatgatggagaattgaaaggtagcaataaa gcaatgttactactatataacgaattaactaaaatacaccttcaaacatatataaataaa agttgtttttcgacgcaggattattccatagctgtattagctggcaaaatgactgacgat tttattgagtatcctattctgaagcagtgctttgcttatttgaaaatcattgaagcctac attaaaacagctatatcgaaagataaagattctctagacgataacgctacttgtaaaata ctacaattcttgaattggagaaatcgattagttaaactgtcacttgaaccaatgtttact atgaccgaaacgagaaagagacaaatcctcagagaagacatcgtgccgttactttacatt catagtaaatgggtacataagtatttagtagaagaattgttttatctgtcgcgtgatagc aatgatattactgaatttgaagatgctgtcaaaattattgaattgaaccgcgatgaaaat aattctaaaatagctaaattgagcaagaaattaagaaaactgtatggacaaccaaagctg tatgtgaatgaacaagaatatgatttgtgtactgcaagaagaaatgtttataataaatta accgtaaacatgaatcagcctttgaaaaaccaattgaacatacttttagcaagtgcaaat actgaaacagatataagttttgccttagatgttcctgatggtgataaattagcactggtc caagaaaatataactaaattgaataaaatgcctaaagaatttagaacaacaggattagaa accaaattgcttccaatcacttcatacattattcaaagagtgattaagatgttgcaatcc aagttctttgttaccataaatcgactaaatgtaaaagaggatatgattagtagtgatgtt tccgatattctgataaacttggtgcacttgggtaagaacacgaaaggattcccgccagct ttgttgaacctgctacaggtcgttcaaagaattcaggcaaaggatcaagaattacttagc caaaggatatcgtcagtcccttcgaaattttgggatgagttttacaagttcctaatcaac tcgccagcgttatatcctatgccattcctaacaataaacaaaatggattctgaggagccc gaagatttgcccgtaaactccaagagggtgtcggataacctgccgctgttaccttattat gttcagaagcttactatcactgaaaacaatcaagatgctcgtcatctattggcttacgag acgatatctttagaagaaagatctgaatattctatacagctggggacaattttgaacatt ttatggaagaatatcgccacattggatacagccgcgaactgcaaactccaaaccgacgca gcattcgaaattcaaaaattcgaagaactcatgctatatttaggttcaattcttaacacc tcaaaggaaaacaacgatgtttctatagaagaaattaaacttaagttgcagcaacatttg aaggacgattccatcttaaacacgcttctgaaaacaccagtgtacgaagaactgaagagg tcgcaaaacgataaaattaaagttaaactactaacatcccacctctcgctgttaacaagc gtcttatcactagtgtttttgtcagaaataaaccccgtagaccacgtcgaaaaatatcga ctcaaacttcaatatatcgaagaggatataaaaatgtttgacgctttattgagtacatat tacatgcacggtttggttactggtactttatcgattacgaaagagattctgaaatcttca caagtgcctgtaacggaattttgtgctaaagaaactaaagatgacctcaagagggtccat ccatattgtagtcatatattagaattaaaggaatccacggcgcagcgagttcagaaatat gcattgggtaataccttcaggcctcaagaaccgtcgtatggcagctttgttaaggattgc aaacatttcgcgaaatcggttctatcgcctcaagcgatgaaaggcattactggaaacctc atcggtatttgttataaactttacgagcatttacaagcgatgtccacagaaaagggtctt gtggaaaacgcacgaacaatagtgaaagaaacctcgtcatggctgtactcggttaatgcg ttctacaggaaattagaaagttcatattccgacgccttcccggaccttgcaaagcccttg caaactgcgatctcacagatcgtatattcggtatcatctctcagggatctggttatagaa atgtcccagaagaaggagcaagggcttgtcctaagtaaagcggtgacagatttgatggtg tatccaaatgttataaatatgagaggtgacaaagaggaacatttgaatagatttatacat tcagatttcgtggcgctgttgaacagaaatgtgttagcgagtgacgatttcaatgcagcg gagcaacagtttatcgaagtactaaaaatgaatttattggagttgcgtatgcactgtacg gcggcggacagaatcgataagatgtctgccgactccatggtgacgatgctcaacgctatt gtgaaggcgtgggacctgcagcaacgggaaatcgagaagaaaaaacaagacgacgaagcg ctatatgttaccaaatcaaaatgcgaggatgaagacgaagaagcaattgcgtatgaagaa atcctcgaaatgttcccctcatattcagaagtcgactttggcgacttcaaacctcccaca ctagaacagaaaattaaaccaaaactcgagcaaaaaactaaaccgaagcaattcatatcg tcagaagatgtttctttagtttacaaatggcattcgagttttgtacgtaacatgactgaa gcggagtggttacccagccgaaagaagttggttggtaacgatataatcagcgcgtttctt cagaggtatcctgtatttagcaggattatacagaacgcttgggatgcgcttgatgccgaa ttggaaggatcgatatctccaagtttgttagtacttgtatcgcagataaaagagaaagtg gacggtcaagattctagtagcagcaaggccgacttctatcattctccatggatctctgaa accaaacaatgtctgccattgctacaaagggtaaaagaaagcaccaacgagctgttagac cagtggccagatttccctacacttaaagagataatcgtaatagtaaacagaatattgagt tttcctgtcactagcccggtgtcgcgattcctaaccggcttagaattactaagagacaag atcgaggaatggaacaggaatgctcataaagggaacaatcttatcgatatatctctagct gtgggacagcaaattatcaattggaggaaactcgaaatgggacattggaaagagtgcctc agcaacttgtattacagaaaacaatccgaagcgcacaaatactggttctacctatacgct gttatcaatacatatttggactctgaatcgcccgacacagtgccggcagaacgagtcata tccgttctcagggatttcatggaaaagtccaacttggccgagtacgaagtccgtctggat attatttacgtgtatcattgtcacttagtgcatctggaggctagcgatagacgagacgag cttctagcaatattatggaacacatacaactactattcacaatttagcgcacaagttgcc gcgcatatcaaagagaagcgtgctccgatcgaaaagaagcttcgagatttcgtcaagatc tgcacgtgggatagagatcttagttattggagtgtgaaggatactgtcgagaaggcacat aaagcgttacacaaacacaccaaagagtttgagagcgtcctgaaggagagcgtggcgagc tgcttggtggacagctcgtgggaggcgagcgcggagcacgtgggcatctgggaccggccc aagcgcgccaccaccgccgcgcccgccggcggcgcctacatgatcgacccgcagaaccat gtcgtactcgccaggaatataaagaaatatctagatcacgccgaacagccctgcgagtat ataacagacggcagcctgttgtccaaggtacctagcctgttgaacaaagcgaagacattg tgcaaagacacgatcacaaacacgtcctatccttcgcttgtacaagagctggatgatttc gtgacgcttgttattgagacgagtacgcatctcgggtctttggaggttgacgcagcatta ccgagagagaaacaaaagtctcaagcaaagaacattgttcaacaaaaacgcaaagcattg gccgatctgttcaaatacctcagtaaattgggactgaactatcgaactggactggtcata ctttcagcgtctgataaagaattgtacgattttacgttaccgcccgttgatttgggtgct gctatcggatatttgaaaagcagacgctgtgatgcaacgctcggtctgttatggacggga tgtgagacatacttccagaagaacatcgcacgacacagactgctcacggcggcgttgcag tcgccgcatcaggatctgggcatgcaaaacatcgaacggtgcaaaggtttcgctgctcag ttgttgaacctaacaaacaaacagaaaaggtcaatatcgaaatactctcgattactctct gatctacgtacagttgcaactaatctaacaaatgctttagacattgacacagcaaagaca aacttaccaacattgaaacaaaagatcgatattcttatcgaatgttacgcaaacactagc atactactcgaacaatttaatatggtactaaaatcttgcccagaaaaaggcgtgggcgct gattacgagcctgattttgactctgtattatccgattccaaaatagttcgttgttataaa aatagcgatgaatggcgtgaactttgtagaaaagtgaaagctctgatagcaaatgttagt aaacagaagaacaatcttcacaaagttgtttatacaactccgaagcaaattggtcaacat gttggggaacttccactggcctcgcagagccacatagatgttgctaatgattgtgaagaa aacttagaaaagctgacgagagatgtagatgatcttttggaagaatatcagtttagatta aaatctcaattgtgcgagcatgtacctcagcatccaatattacgcagcatggtagaactg tctcaatatttgaaagatacagtaaaccaacttggagagttgaacaaagattctgatgtt cctatggattctataacaagtgacgatctaataaaccaaactgaagatttgattgccact atgctgttgatagtacaatctgtgtacaagagacacttaccgatcaatgaaaatatggaa gttattaatgctattgatgaaataattcaaagccaagataaacctgagtccagagatatc cttgaagacaaacatttgaaggagcgtctacatgataagttatccaatgattctaaaatg ctccagttagattctttgattaataaaacatataatgttttaataaactatgtacaatat gtagccaaaggtagcaaagacatagatgaagtaaagaacgtagttatgagatcaattccg atattggagcaaattgtattgtttgtgcaatatttcatttcacaaaaggttgcagttcac agagtgtcgtgtaaaatgttatcagttttattgaagatattctcagatcttgcttctaaa ggtttctgtaaaccatccgatcttgatatggaagagggcgaaggcgaagggggacctggg aagctctccggtggcactggacttggagaaggagagggacagaaagatgtttccgagaga atcgaaaatcaggaccagctagatgacgctcaccgccctggagaagagaaaaaagaagaa gatcgagattgtaaagaggaagagaaaggaattaatatgactgatgactttgattcccat ttacaagatgtggaaaagaaagagggcgatgactctgagcaagaagacgacgaagatgac 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agcaaggagctggccttcgagagtcttgctcttgtttcacaggcacttaatctcctcgaa tccggcgacctggcagtcattagcttcggcgagaaaccaaacctcctgcacccgttcacg gaacaattctcagaacattccggatctaagatattagaacaattacggttcgaacaaacg aagaccaaaatagctcaattattagacttttgtacggtgttattcgaagagcagacagtg aggagtgacgctgtcaacgcaaagttgttggtggttgtgagtgacgggagagggatattc tcggagggcgagacgcgggtgatgcatgcggtgcgcagggcgagacagcaaggaatattt ttggtgtacgtcatcatcgacaatccggataataaggactccatcatggacatccggcga cctatcatcgatccagcaacaaactcgttcgtaaggttcgagtcgtatttagattcgttc ccgttcccgttctacctcatcctgcgggacatgtcggcgttgcctactgtattgggagac gctctgaggcaatggtttgaactggctgctaatactgcgagttaa

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