Manduca sexta (tobacco hornworm): 115447492
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Entry
115447492 CDS
T07401
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
msex
Manduca sexta (tobacco hornworm)
Pathway
msex00230
Purine metabolism
msex00670
One carbon pool by folate
msex01100
Metabolic pathways
Module
msex_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
msex00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
115447492
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
115447492
Enzymes [BR:
msex01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
115447492
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
115447492
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
115447492
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
AIRS
GARS_N
GARS_C
CPSase_L_D2
ATP-grasp
ATP-grasp_3
ATP-grasp_4
ATP-grasp_2
LAL_C2
Motif
Other DBs
NCBI-GeneID:
115447492
NCBI-ProteinID:
XP_030030440
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All DBs
Position
14:complement(1473395..1503152)
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AA seq
1366 aa
AA seq
DB search
MTESNVLVIGSGGREHAICWKLAESPNVKHIYCAPGSVGISTTNKVESVELDIKNYPALA
KWCKDQSIDLVVIGPEDPLANGLVDNLTQYGIPCFGPTKAGAQIEANKDWSKKFMNKYQI
PTARHKSFTDAAAAKEFINSAPYPALVVKASGLAAGKGVVVASSKEEACQAVDEILTDAK
YGSAGEIVVIEELLEGDEVSVLAFTDGETVSMMPPAQDHKRIGDGDTGPNTGGMGAYCPC
PLITPDQLADVKDQVLQRAVDGLKAEGIKYVGVLYAGLMVTKSGPMTLEFNCRFGDPETQ
VLMTLLDSDLYNIMKACVDGTLKQIQVQWNTKLSSVGVVIASKGYPETSTKGCVISGLSQ
VQSNPGVVVFHSGVARGANGSLVTWGGRVLAVCARAGSLRAAAAQAAAAAAAIDFPGAHY
RKDIAHRAFSKINGLSYLQSGVDIDAAATLVREIEPLATATHRPGVLGRLGCFSGLFQLS
AMDPKLKDPVLVQGTDGVGTKIKIAEIMKKYDTIGQDLVAMCVNDILCAGAEPFAFLDYI
ACGRLQLDVATTIIKSIADACIMSGCALLGGETAEMPPMYEVGKYDLAGFAVGVVDSDKQ
LPRADSICAGDVVLALPSTGIHSNGYSLVQKIMIETGHRFNEPAPFSTSNKTFGEEFLVP
TGIYVRALLPAIKKELIKGLAHITGGGLLENIPRILPASVKVKIDADKFGIKPIFGWLQA
KGLVSDFEMLRTFNCGVGMVVIADEKDVPELLGMVEDLKVIGVVEEMGKEGGHQVVVENF
KQAMTPLTTPYMRGDCMPQKSLSYKDSGVDIEAGDSLVSMIKPLARSTTRPGVLGGLGGF
GGCFQLKAIEREYKDPVLVVAAQGVGTKLKVAQKARRHGSVGADLVALCANEVVCLGAAP
VTFLDYFACGALDVRTAAAVVAGIASACTKAGAALLGGETAEMPGMYEAGVYDIAGFALG
VVERAQILPKINDINVGDIIIGLPSSGVHSNGFSLIHKLMKKSGLTLEDKAPFSQEGLTL
AEELLRPTRLYVSAARAALRTGRVKGAAAVAGGGLVTAVPRLLPAHARARLNAHWWHVHP
VFAWIADAGAVQDDEMLRTFNCGIGLVLIVSPEDQAEVMNATRSHGAMVIGSVQARPAGG
ARILVDNFASAIDFTRRVPLLPKKKVAVLASGNGSNLQALIDTTLDTSECVCAEISLVIT
NKRDAYALQRAEKHGIPSLVFNHKDYSSREEFDRAVSAALEAHRIDLVCLAGYMRILSAE
FVQKWHGRLINIHPSLLPKFPGLHAQKQCLDAGEKESGCTIHFVDEGMDTGPIILQECVP
VLPSDTEESLTQRIHSAEHRAYPRALRLLATGRVRLNAQGHIMWYQ
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgacagagagcaatgttctggtgattggtagcggaggtcgggagcatgccatatgctgg
aaactggcggagtcccccaacgtgaagcatatatactgcgcgccgggcagcgtcggcatc
tctaccaccaacaaggtggagagtgtcgagttggatataaagaattatcctgccctcgca
aaatggtgcaaagaccagagcattgatttggtagtgattgggcccgaagaccctctcgcc
aatggtctggtagacaacttgacgcagtatggcatcccatgctttggacctaccaaggcc
ggcgcccagattgaggccaacaaggactggtccaagaagtttatgaacaaatatcagata
ccgacggcgaggcacaagtcattcactgatgctgcggctgcaaaggaatttattaatagt
gccccgtacccagcgctggtggtgaaagcgtccggcctcgccgccggcaagggtgtggtg
gtggcgtccagcaaggaggaggcatgccaggccgtggacgagatcctgacagacgcgaag
tacggttcggctggagaaatcgtggtcatcgaggagttacttgagggtgatgaagtttcc
gtactagccttcacagacggcgagacggtatcgatgatgccccccgcgcaggaccacaag
cgcatcggggacggggacacgggccccaacacgggcggcatgggcgcctactgtccctgc
ccgctcatcacgcctgaccagctcgctgatgtcaaggaccaggtgctgcagcgcgctgtg
gacggactgaaggctgagggcatcaaatacgtcggagtactatacgccgggttgatggtc
accaagtctggtccgatgacgctggaattcaactgtcgtttcggcgaccccgagactcag
gtccttatgacgctgctagactcggacctctacaacattatgaaggcgtgtgtcgacggc
acattgaaacaaattcaagtgcaatggaacactaaactatcgtctgttggagttgtcatc
gcgtccaaaggatacccggagacttctacgaaaggctgcgttattagtgggctgtcgcag
gtgcagtcgaaccccggcgtggtggtgttccacagcggcgtggcgcgcggcgcgaacggc
tcgctggtgacgtggggcgggcgcgtgctggccgtgtgcgcgcgcgccggctcgctgcgc
gccgccgccgcgcaggccgccgccgccgccgccgccatcgacttccccggcgcgcactac
cgcaaggacatcgcgcaccgcgccttctccaaaatcaacggcctctcctacctgcaaagt
ggagtagacattgacgctgcagctaccctggtccgtgagatcgagccactggccacagct
acccacaggccgggggtgttgggcaggctcggatgtttcagcggcctgttccagctctcc
gccatggaccccaagctgaaggacccagtacttgtccaaggcactgatggagtcggtact
aagattaagattgcagaaataatgaagaagtacgatacgatcggtcaggatttagtcgct
atgtgcgtgaacgacatattgtgcgcgggcgcagagccttttgcgttcctggactacatt
gcgtgcggccgcctgcagctggacgtagccaccactatcatcaagagcatcgctgacgcc
tgtataatgtctggatgcgctttgttgggtggcgagacagcagagatgccgcccatgtac
gaagtgggcaagtacgacctggcgggcttcgcggtgggagtggtggacagcgacaagcag
ctcccacgagctgattccatctgcgctggggacgtggtactggccctaccctctactggg
atccacagtaacgggtacagtctggtgcaaaaaatcatgatcgagacggggcatagattc
aacgagcccgctccgttcagcacctcaaacaagacattcggcgaagaattcctcgtacca
accggtatctacgtgcgggcgctcttaccagctatcaagaaggaacttatcaagggtctg
gcgcacatcaccggtggtggtttacttgaaaacattcccaggatcctgcctgcgtcggtc
aaggtcaaaatagatgctgacaagttcggtataaagccgatttttggatggctgcaggct
aaaggcttagtgtcagattttgagatgctacgaacattcaactgcggcgtgggaatggta
gttatagcggatgagaaagacgtgccggaattgttgggcatggtagaagacttgaaagtc
atcggtgtggtcgaagaaatgggcaaagaaggtggtcatcaagtagtagtagagaacttc
aaacaagcaatgaccccgctcaccacaccgtacatgagaggagactgcatgcctcaaaag
tctctgtcgtataaggacagtggagtcgacatcgaggccggggactctctcgtctctatg
atcaagccactggccagatcgacaactcggcctggtgtgttgggtggtctcggaggtttt
ggtggatgtttccaattgaaggcgattgagagagaatacaaggacccggtgctggtggtg
gcggcgcagggcgtgggcacgaagctgaaggtggcgcagaaggcgcggcggcacgggtcg
gtgggcgcggacctggtggcgctgtgtgccaacgaggtggtgtgcctgggcgcggcgccg
gtgacgttcctggactacttcgcgtgcggcgcgctggacgtgcgcacggcggcggccgtg
gtggcgggcatcgcctccgcctgcaccaaggccggcgccgcgctgctcggtggtgagaca
gctgagatgcccggcatgtacgaagcaggcgtatacgacatagccgggtttgcgctggga
gtagtggagcgtgcgcagatattaccaaagattaacgacatcaatgttggtgacatcatt
attggtttaccttcaagtggcgtacacagtaacggcttcagtttgattcataaattaatg
aaaaagtccggacttacgctggaagacaaagcgccgttcagccaagaaggattgactttg
gcggaggagctgctgcggccgacgcggctgtacgtgtcggcggcgcgcgcggcgctgcgc
acggggcgcgtgaagggcgcggcggcggtggcgggcggcgggctggtgacggccgtgccg
cgcctgctgcccgcgcacgcgcgcgcgcgcctcaacgcgcactggtggcacgtgcacccg
gtattcgcgtggatagcggacgctggcgctgttcaggacgacgagatgttgcgcaccttc
aactgcggcattggactcgtgcttatagtctcccccgaggaccaggctgaggtgatgaac
gcgacgcggtcgcacggcgcgatggtgatcggcagcgtgcaggcgcggcccgccggcggc
gcgcgcatcctcgtcgacaacttcgcctccgccatcgacttcacgcgccgcgtgccgctg
ctgcccaagaagaaggtagcagtactagcttcaggcaatggcagcaacctgcaagcccta
atcgacacaacccttgatacgtctgagtgcgtgtgcgcagagatctcgctggtgatcacc
aacaaacgcgacgcgtacgcgcttcagcgagcggagaaacacgggataccatcattggtg
ttcaatcacaaagactactcgtcccgcgaggagttcgaccgcgcggtgtcggccgcgctg
gaggcacatcggatcgacctcgtgtgcctcgccgggtacatgaggatcttgtccgcggag
tttgtacagaaatggcacgggcggctgatcaacatccacccatcgctgctgccgaagttc
cccggactgcacgcgcagaaacaatgccttgacgcgggtgaaaaggaaagcggatgcacc
atacactttgttgacgagggcatggacacgggcccgatcatcctgcaggagtgcgtgccg
gtgctgccgtcggacacggaggagtcgctgacgcagcgcatccactcggcggagcaccgc
gcctacccgcgcgcgctgcgcctgctcgccaccggccgcgtgcgcctcaacgcgcaggga
cacatcatgtggtaccagtaa
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