Manduca sexta (tobacco hornworm): 115448899 Help Entry 115448899         CDS       T07401                                  Name (RefSeq) LOW QUALITY PROTEIN: titin   KO K12567   titin [EC:2.7.11.1] Organism msex  Manduca sexta (tobacco hornworm) Pathway msex04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:msex00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     115448899  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:msex01001]     115448899   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:msex04131]     115448899   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:msex04812]     115448899    04147 Exosome [BR:msex04147]     115448899 Enzymes [BR:msex01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      115448899 Protein kinases [BR:msex01001]  Serine/threonine kinases: CAMK group   MLCK family    115448899 Membrane trafficking [BR:msex04131]  Others   Actin-binding proteins    Others     115448899 Cytoskeleton proteins [BR:msex04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actin-binding proteins     Others      115448899 Exosome [BR:msex04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    115448899 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig V-set fn3 V-set_CD47 C1-set C2-set_2 BiPBP_C Ig_DSCAM-DSCAML_C Pur_ac_phosph_N SH3_1 SH3_9 NDNF F5_F8_type_C_2 Motif Other DBs NCBI-GeneID:  115448899 NCBI-ProteinID:  XP_037300057 LinkDB All DBs Position 27:11594127..11697792 Genome browser AA seq 16217 aa AA seqDB search MEKQSRWSEQRSEQREQVVQQQERVQRTEHHFTRQMLMQHQVESTGESLPIAGGRPGDPS PPIFEQIFKNARFAQGGNAKFEGKLRGNPTPVVSWTRKKAPLVECNKYSMSYNEQTGDVS LLIKQIGPGDEGEYTCTARNQYGEAICSVYIQPEGVPMPAHQASQQQSYRHVSETVEHKS YGTQGYSSEQSRKMQKVAYTNGTDYSSTEDFKVDTFEYRLLREVSFRESITKRYVGESDI HISTEIDKSLGPVSPPKIAQKPRNSKLQEGTDAQFQVQLSGNPRPRVTWFKNGQRLVNSS KHEIVTTNNQTTLRVRNTQRSDSGHYTLLAENPNGCIVTSAYLAVESPQESYVHDQKSQY TIDTQQVGIEERVEINEKALAPQFVRVCQDRDVTEGKMTRFDCRVTGRPYPEVTWFINDR QIRDDYNHKILVNESGNHALMITNVDLNDSGVVTCVARNKSGETSFQCRLNVIEKEQVVA PKFVERFSTLNVREGEPVILNARAVGTPTPRITWQKDGVPIIPNPELRINTDGGASTLDI PRAKASDAAWYQCTAQNVAGSTATRARLYVEVPKEPAPEQKRLHLPRPTKIIEPEPAPGP EIIYLRHVERARPYVPPGEEDRVYPPPQFIVPLKSVTQMEGGKIHFETRIDPVGDPSMKI EWLKNGQSIEASSRFTSIFRFGYISLDMLSLNIQDSGEYTCRAVSATGVAETKATLHVTP RATIDRTSQHPETLQYLQHTEDYSKYQHQESIEEQVSQRPQFIRPLQDLGELQEGRNAHF EAQLIPVSDSTMRVEWYKDGRPITASSRITAIFNFGYVSLNIMHLRAEDAGSYTVRAVNK LGEAVSTASIRVAARSTVTGDLGIPEQRRYIEKTEQLEAYQQQQHQKYYQEVPESTQGPE FKTPIKDQINIKEGGFAHFEARLEPIGDSTLRVEWLKDGRPVEASSRITTFFNFGYVALT IKSVTVHDAGHYTCRAYNALGQASTSANLTIVTKKDIIAESQHPGGLEKIQYLEDSSRYS RRMDEEVKVTQKPRFLGPLKGTNKIVEGQGAHFEARVEPQSDLTMTVEWYFNGKQITSAN RIQTYHDFGYVALDIANVREEDSGVYTVVARNAAGEAQLSASMSVETRSSIDTSSIHRGL YEKTRQIEESKFVEPSYHIEEISKSKPVFVQPLSDPPPVTEGKNIHLECRLEPMGDPTMR VEWFHNGRAVTVGSRFRTYYDFGFVALDIIHATSIDSGEYTVRAVNHLGSAHTSAMVRVI ERSDIVTDTQNEQAIEQIQILEDAARRSRQVQEDITVMQAPQFSRPLHNIETVEGTNVHL ECRLQPVGDPTMKVEWFCNGKPIKTGHRFRPAYEFDYVALDLLSVYPEDSGVYTCQATNQ LGEAVTSCALRVIAKKDLIFESQHPSGLEKIQYLEDASRYKKSEVIDEAINIKPRFVTKP KSIENVIEGQHVHFECKLEPVTDSNLKVEWFKNGHPVTIGHRFRPIHDFGYVALDIIDLI AEDSGVYTCRATNLVGADEVSCRLTCRGTADIIRATQNEAGLEQIQVLEDRSKYHRTDFV DEVTTQAPIFTTSLKNVEIKEGQRAHFECRLIPVSDPTMKVEWYHNKTPLKSGSRFTETN NFGFVALDIMSCLPEDSGTYTCRAINALGEAVTSGIAVVHSKKSIYLESHHEGALPRLNQ LEDTSRYQKHGVQDEVVTQAPVFTMPMKDIRVAENQAAHFEARLIPVGDPKLRVEWLRNG VPIEASNRLTTMHDFGYVALNMKYVNPEDSGTYTCRAINELGEAVTSSTLFVQSKASLQL ESQHETALEKIQLLEDSSRYRRKEDVEVAVNQPPRFITQLNGPSKLVEGQSAHYECRIEP YPDPNMRVEWYFNSKVLQSGHRYRTAYDFGFAALDILTVYGEDSGEYTCKVINNLGQATS SIKLNVQSKESIIRDTQHESALEKIQYLEDDSKYKRVIRDESFVAEKPQFGKPIKNVQVG EGQPVHLEATLTPVNDPTMRVEWYCNGRPIQQGHRFKTTYDFGYVALDILYAYAEDTGTY MCKATNAVGEAVTTSSVNVDAKSGLYLDTLDEQRLKKIQELEKYERPKPAEVEQPGQRPV FLTALTSLEHLKEGDRAHFECRVEPINDPDLTIEWFLNGQKIRAGHRYRTTHDFGYVALD ILYTYAEDSGTYMCKATNKLGEAVNTCTLKVAGHRSIILDTQHPNGLEKIRQLEAQGHHT RIEVEEPKISPPRFVTELTGTTHVFEGQTAHFECQVEPVHDPNLRIEFYHNGKALQSASR FHITFDFGYVSLHIQHCIPEDAGEYSVKAINALGQCTSSISMTVTAKGSIISESQRPEGL EKIRELEPSEPFKRPEIPEPVTRQRPVFTQPLQNIDNIQEGQTAHFDCRLIPVGDPTLKI EWFRNEKLIEDSSRITKTHDFGYVSMTITHVRDEDQGVYMCRASNLLGEAVTTAAMKIKT KAAIQMETQHPEGMKKIQQLEEPQRKKPEEPEREFEKPIFTQVLTGPTELWEGQHAHYEA RVVPVGDPSLRFEWYINGVELKMGSRFRTTHDFGFVTLDINSVVAEDAGLYMCKAINRAG STVSSTSLKVKTKSTIVDQAMRPESWEQIQLKEAAMNKVPEMFVDAGVQQAPIFTTHLKS LDKFVEGQHVYLEAQVEPRTDPNLRIEWFKNGVSLTTGARLKSTFDFGLVTLSINGLRID DSGIYTCKATNLIGEAVSTTSIKVEDRHWLLGDSLHPESLDRIGALEQPKPGKPEAPEPV YEIPVFISHLNNIICKEGDNIHFECNVEPSRDPTLKIEWFFNNKPLPSGSRYKSTHDFSY VSLDITHTYEEDSGIYTCKATNSKGSATTSGSLRCTGDRNIYLDTQHPQGKAGLEAVEQA EEARLSKSRRASVPDVEYPKPEWIVPVAPEHQLIEGQALHLEGQVEPKNDPDLKIEWYFN GKVLEQGSRFKLTSDFGFVTLDLIDVYERDSGIYTCKAYNKRGEAFTSSTVYCTSKENLI ERTQHPKGTEGLEKIQNLEDSLRKEPGQKPDDDTGRPPEFTSVFKDIVDISEGQIAHYEA SLIPTGDQSMVIEWFYNGKTIEASHRIRTVYAFGMVVLEILGTKTTDSGVYACRATNRWG QAEISVKLECVDKSKGQKPRFTTHIQNIDGLKDGQSAHFECTVVPVDDPDMKIEWYHNGQ PLRHSTRIKTVSDFGFVVLDIAYTQNHDTGEYVCRAYNKYGEDFTKATINCYGRGGVYLD SLQPDSLAKIRELESLQGAQQQAPVTPSAVPPKFITQIQDVTKLVEGQSAHFEARLVPVD DPDLKVEWFYNGKKLPHGHRYRTFHDFGIVILDILYCYEENSGEYECIATNKLGRDSTKA TLKCTSKENLILDSQLPRGMEGGLEKLQTLEDSMIRRKDDQIEEEKGKAPVFTVPLSNIE NLREGENAHFEARLTPTDDPNLKVEWYWNGKALKAGSRFRTFCDFGFVILEISPTYPEDS GEYLCRAYNNYGEAVTTATMKVQGKRNIILESQLPKGMEGTIDKIAALEGYTGTVDSMTP EAESGNPPEFITTPSDLILTENSSAHFECRLVPVNDSSMRVEWFHNGKPLLTGSRVKTIN DFGFVILEIGGVYQRDAGLYTCKATNRHGEATVSCKLQVKGRQGIILEPQLPSHFKSGTE SIQKLEETLHKREEITIEDEKPNPPRFTVEIKDNIDVPEGGPIHFDCRVEPVGDPTMRID WFHNGRPFATGSRVHMLNDFGFIALDIDYIYTRDAGEYTCRATNKWGSATTTAKITCSAK RDIVLDSQLPQGMSGEKIKELERGRVSDVPKEEPVVSTPPKFITQIQSHTVEESEGVRFE CRVEPKEDPKLRIEWYRNGKLLPTGHRYRTVYDMGFVSLDILYVYAEDSGEYVCRAVNDF GEDFTKGTISCKKLPDIILQNQVPRGMKKSEALTQMEATIKKYTSEVFLTEDDLYDVDKK QPPRFVTQIQSQTSLVEMESTKFECQLAPVGDPNMKVEWFFNGKPLLHKNRFEPIYDFGY VAMNFGWVYPEDSGEYVCRATNLYGMDETRAIIKTAGKPGIVYDSQLPKHMKSIEKIREM EAAWQMAPEPAPEETKARCPPVFVSRPDPVTVEEGEWARFCCRVTGHPKPRVMWLINGNT IVNGSRYKLTYDGMYHFDIPKTRQYDTGKIEVIARSSAGEAMAVTELKVISRHDDYRGVL KNAPRPWYDETTQYQRSETELEKTFEERQALQRQGVIDHRPELKPKVIKEPETEWQQTVK KKKSEEYYNKLQELENEQVIKESRFRESTHQYAIPGEKIASTSIAKGMAQRYEDSLEQTE EIVDQKVQKRVVQKPRIPDPSESTVHGKEVHVAKQKQIQKEVVGDTEITRKITSTETTEI EHKAQTQERVVEGPVKPSKPPVFTKKMQPCRVFEHEQARFEVEFDGEPLPIIKWYRENFP IKNSPDFQIHTFSTKSILIIRQVFVEDSAVFAAVAENRGGTAKCSANLVVEERRRQGRGG VTPPSFTLTAQNVNVTAGQLVRFDTKVTGTKPLDVYWLKNGKKVQPDIRNKILEEDGTYT LLILEAYPQDSGKYECVAINSAGEARCDAECSVNAPATKDKPKPQTKAMNAPPEILEPLK DKVVTEGQAIEFSCKIVGKPVPTVQWYKGDKLIKPSKYFQMSRTSDEYTLRISEAFPEDE GDYKCVAYNSAGRVTVAAKLKVTQPDQAENLPVLTPLRDIVVYEGQPAQFKTHIQSKVKP TIQWLREGALIPETPDFQMIHEGNNAVLLIGNTYEEDTGTFTCRATTAAGQAETSAKLVV KKSRTTTRKTFQDRTDVKITSTSDTDDTVSKSMFQSTEESNILKLESVQDVDTQKLTKTV PWRKKIQEDSLELQKTIETKHWRKSRADKQSHLEKYTLSDDSTILGLDETTDTKVKDDSL VTKTWRKPRTSDTRKSVDKNIITQDEVAVEENLEVKHWRKPREKEEPSPTGKEVEATTKL DVEETIRWRKRRSEEKQQIASTQERQEPLPWTQESIKLRPTKVEKSAIIKEKVEDVTLKH IRKDSIQKTEKEHLKEERTQEEVFLKPIPEPKVPEEEKPEEVQLKPVKKEKPVEEAAPEE RKWPAGXRRPKEEEHKEEVILKPIPKQKVPEEEKPEEVQLKPVKKEKPVEKAVPEERKWP TGRRRPKGEEHKEEVIQKPIPKQKVMPEEKPEEVQLKPVKKEKPVEEAVPDEHKWPTGKR RPKEEELKEEVILTPVPKQKVPEEEKPEEVQLKPVKKEKPVEEAVPEERKWPTGRRRPKE EESREEVILKPVPKPKVPEEEKSEEVQLKPVKKEKPVEEAAPEERKWPAGKRRPKEERTK EEIILKPVPKQKVPEEDKPEEVQLKPVKKEKPVEEAVPEEHKWPTGKRRPKEEELKEEVI LKPVPKPKMPEEEKPEEVQLKPVKKEKPVEEAVPEEHKWPTGKRRPKEEELKEEVILKPV PKQKVPEEEKSEEVQLKPVKKEKPVEEAVPEERKWPTERRRPKEEEPKEEVILKPIPKQK VPEEXKPEEVQLKPVKKEKPVEEALPEKRKWPAGKRRPMEEEPKEEVILKPVPKQKVPEE EKPEEVQLKPVKKEKPVEEAVPEEHKWPTGKRRPKEEEPKEEVILKPVPKQKVPEEEKPE EVQLKPVKKXRHPAEAVPEERKWPTGKRRPKEEEPKEEVILKPIPKQKVPEEEKPEKVQL KPVKREKPTEETVPKERKWPTGRRHPKEEEHKEEVILKPIPKQKVPEEEQPVEVQLKPVK RDKLVEEAVPEERKWPTGKRRPKEEEPKEEVILKPVPKPKVPEEEKSEEVQLKPVKKEKP VEEAAPEERKWPAGKRRPKEEEPKEETILKPVPKQKVPEEEKPEEFQLKPVKKEKPVEEA VPEERKWPAGKRRPKEEEPKEEVILKPVPKQKVPEEEKPEEVQLKPVKKEKPVEEAVPEE HKWPTGKRRPKEEELKEEVILKPVPKQKVPEEEKPEEVQLKPVKKEKPVEEAVPEERKWP TGRRRPKEEEPKEEVILKPVPKQKVPEEEKPEEVELKPVKKEKPVEEAVPEERKWPTGKR RPKEEEPKEEVILKPVLKQKVPEEEKPEEVQLKPVKKEKPAEEAVPEERKWPTGKRRPKE EEPKEEVILKPIPKQKVPEEEKPEEVQLKPVKKEKPVEEAVPEQRKWPTGRRRLKEEEPK EEVVLKPVPKQKVPEEEKPEEVQLKPVKKEKPVEEAVPEERKWPTGKRRPKEEEPKEEVI LKPVLKQKVPEEEKPEEIQLKPVKKEKPVEEAVPEERKWPTGRRRPKEEEPKEQVILKPI PKQKVPEEEKPEEIQLKPVKKEKPVEEAVPEERKWPTGRRRPKEEEPKEQVILKPIPKQK VPVEEKPEEVQLKPVKKDKPDEISKEDDLPEEEKPKTIEEVQKKLKKIVVLEESIEDNKA EEVSVATQVEEKTIEEQETIKVKKQIVKKKIEKKKETEEVGPFIIEPLKALNVLERDSFE LTVTFVSEDDTKVTWFRNNKPLEESDDCEISTANGISTVKIYNTEKKKLGKYEVVIENKN IIAKSASSVKLVKSIDENQILPPIFIKSLHPCNVCLGDIVLLETEVLSSPSASFQWFIDT KEVTSYAKQNKLNNIYVSNKDNVSNLCIENITNDLLGIITCRAENFAGSVSTSASLILKD KDQKYGDVPTLINPLESISIMDGEPILLTCKILGQPWPKIEWYHQGKPIQRARDITTSRY TSGCCELYIKEAFPEMSGNYKCIATNEFGCCNSECTVNVEAYEYVPSMSEEDILSDEKTS DIEEFAPRIVKALPTVVTTTEGELTRFEAKAIGMPKPEIKWIKQGTVIVTSQEYQIEELD DGTSILIIPEVYQDDTGEIVFEAHNPLGVTSTIAALSVESIVGTKEYRKPEWVTHMEELQ AALKASQAVPTFVKEITGERVQEEECVTFEAIYSGNPTPEILWYKDGKVIRTDERFIVEN KDKRTTCTIRKAVKELEGVYMCKAVSEIGMAVTKAKLQVFEDGEKIRKSKKSKEKIKKER IFKQEDEIETVETKADTVLIRDTTDSQLSEIKPIEDVAEEKAEVVITEADHVETVDVASY KKVDKKEKITPKTHKVKPIVTPHDYLVSSQQQKEETVQPFEDTYKTQKGVIKLVESDTRM VAEINELLEVINAKEFGPGESPLRELAKIGYMLRKGITTDEIESLYDSQYFPALRVPQSQ SALVRLVERQGHGALITEVLTEETAQDENVIASKAGFRAFLKMVELKHSSVEEVIAHFYP EDFKPRSWEQKEAHEVIEETKAEEIAETHTPKVIKDTKTPEKVVLRDAKEKEQIKRKKYT KQKIGLEEIQMEEDLELEKVKIIKALQPKEKQEINEEDQLDEFEKDAVPYITTIAADIPD NKIEVIAANEAPHLQPEKIIENVTANLKFNTNNRIAIISDIQQFEEKETPLELKETSKSI IKSTVSEIEPLVVTEIETSGMLDEYHANKTKLENKAEKSFITSENIVTLETHADMSVSKF DVDNNDKQMEKAKTTLLLKDAINVSESISSSKESPLEDVITKQSVASVGYTTLLGVSVSE VNEEIKEKDVEYFNKEKAATSKLNFNLLEPLEVGEVFVEDKSGKYYPELIVPTETARKDI LVSNQIVTEIHDVQEREGVLSALKIPPAQEAYVDITSKDSIVVRIEESHEKEEDLPLQQK PTLFSVENDLTLHTSLNNIVTTSHIKETEFIPEPVPTKKATIGLNELQHKFNLETNINDS EQSFEGQPSISKTHAEISISVLDKNVIEEVQVHESEKDLVIKDDKQTAAAQIDIKTIESI IMSETIGETSVDNMKTSQHIPSELASETLVTDNAKIISAPFVHERETTEEYRSRKPEVVI TTLIPNIPVAVLETEYSESDDKLSVNKLPESAHAHLGSTHHLKSPISQEVNTADQIDFVN MPVKMTETATEQRDLQKEITVLQTTIQEQLQTLDQNTVHETKAQTTFISSDSINITEIIP NICGQDLESGKEKPKVFAKVDFDSDHKIAITSEVTPKDTLGHLDSVSRDYEEAQILSNNL TSLQVSESNIYDSQAYLEKDVKPDLKFVPLDIVHSEGILNVTEVVHHEKESDYNTMLSPE TFKAAPNVTVRPVAVSTEITADSSIEYTIQDDVRETKKANVENIAHKEVIISTTECNEKE DIFRASTLPSVAEALMCVNPNQAVQIEVNQSEILPSLLDRLDKTPSVKAGRTTTTLEAIT QEEVLLHLSEGVLSEKQTDFTIQPNVSVNALQVPEYNEKVIIETENIFDTPSVPDQQKAA LTIISKQGIETSEIVSQSDNLEKVADFDIQYKKASLKIDDNYGKIANTEETIPSLLTEDF KREIIPLEKPGILSIGKTAIEKTEIVVGESEKNLLEKKPLPSKITTEFTETQAYITSTVE TVDKENELELQTSVVKRDALVGVVPLNTTIDTEVITGNSVDNLEDKVRKTYQASIKQDEL EKYVQGMEITHGEKESDFVDLKEDLQEATKAIVQATAKEVTEIYTNEKEKDMQKIFTSSS VHAQTSVNEQLSLVSTEVMFVQNANVLDIPDSSPVKALRIHGTQEAIKKTEPFIGEVEDD FISEMPIHKTGKGSIDEQKPLDVTEIIPTESETKLSDYTIQRGETTKLTIQSKNYVDVLE ITSSEKEDNLQIMENLVETKSIEPEFSVHSSIKVNETVPSEGGIVFILPSDHKTQQADVT LQPSDYLRVSENIPEENEYDLKQDMLPKKTVNEFTLDTLQHLNVQIHQTTEAEVELSRSQ PTKSEVSDFTIEPVSALQISEIQSEEIQEILLSDKAKLSKPALNLEPGQHITVTEVETQE KEVPLKPDVPKDETLLPKQMTFQEIVNLQPQTIESISKLETLYQPESNKIEYEIELHKSY HTAENVIHESPTDIESDKKEQRIADKRIIELKHLEQIEIITDEKSETLNLISTEIKDKAE AKHISLTEITNIRPEILENVKEIVSILKPDEKMTKQITEQILEIKPIEQTEIFIGENVET IKSLPQQEKSIDAKPVAVYPISQSSILVHESETIISSEKPTQAENANVCFNTNQSVIIEE AIHDDSEFSFVTDKEMPKTAEKTITPLAHVQCTENILGSQLTELITPTIQTETTTATPTA IIPLVITDKEYIQHETELLVQKPKHQKIKEGLKVSSEIEVTSEFVTEEAQSYIPKSPKLV KSAVASTDAEHHEIIISEQETHIDEKSEIASISSKSSDVEETEEIITKFTKSPGTSEPKQ IKTKRTIIRKKKKTANKDLIEGDVVIEETLDDDEPKEITEQKHEVNIEEYDGDEPHPMED SEKSKIEMPDEYLNIPKLTSQVQIEEVVEDDLSQKQSTKSVKRKLKQKTTFTDKQYEEAI VEKEKPLLKTVLDKEKPVPREQKQEEIIELPEETTVEEIKSKEGKPKQRKITKRIIKKRV GTKLETTQITTEQDDDETPVISVHKTEELVDDTTIPHEDLHKPEKTKPIEEAPEKVEITQ VRTETGDIKTIKTTKRVIKKKRGPKEEVTEITTIEKDDEAPITTVTVKEESAPEEIKPVE IVELPEETTVEETETPEGKPKQRKVTKRIIKKRVGPKLETTQIITEQDDDEQPIISIHKT EELIDDTSTPLAELHKPEKAKPIEEAPEKVEVTQVRTETGSVQTIKTTKRVIKKKKGPKK EVTEITTIEKDDEAPVTTVSVKEESTPEEAKPVEVVELPEETTVEETETPEGKPKQRKVT KRIIKKRVGPKLETTQITTEQDDDEQPVISVHKTEELIDDTTTPLADLHEPEKAKPVEEA PEKVEVTQVRTETGDVKTIKTTKRVIKKKRGPKEEVTEITTIEKDDEAPVTTVTVKEESA PEEIRPVEIVELPEETTVEETKTPEGKPKQRKVTKRIIKKRVGPKLETTLITTEQDDDEQ PIISVHKTEEIIEDTTTPLADLHEPEEAKPVEEAPEKVEVTQVRTETGDVKTIKTTKRVF KKKRGNKEEVTEITTIEKDEEEPVTTVSVKEESAPEEAKPVVVVELPEETTVKETETPEG KPKQRKVTKRIIRKRVGPKLETTQITTEQDDDEQPIISVHKTEELIDDTTTPLADLHEPE KAKPVEEAPEKVEVTQVRTETGDVKTIKTTKRVIKKKRGPKEEVTEITTIEKDDEAPVTT VTVKEESAPEEIRPVEIVELPEETTVEETKTPEGKPKQRKVTKRIIKKRVGPKLETTQIT TEQDDDEQPIISVHKTEELIDDTTTPLAELHKPEKAKPIEEAPEKVEVTQERTETGDVKT VKTTKRVIKKKRGPKEEVTEITTIEKDDEEPVTTVTVKEESAPEEAKPVEIVELPEETTV EETETPEGKPKHTKVTKRIIKKRVGPKLETTQITTEQVDDEQPIISVHKTEELIDDTTTP LADLHEPEKAKPVDEAPEKVEVTQVRTETGDIKIIKTTKRVIKKKRGPKEEVTEITTIEK DDEEPVTTVTVKEESAPEEIIPIEIVELPEETTVEETKTPEGKPKQRKVTKRIIKKRVGP KLETTQITTEQTDAEQPIISVHKTEELIDDSITPLEDLHKPEKAKPVEEAPEKVEVTQVR TETGDIKTIKTTKRVIKKKRGPKEEVTEITTIEKDDEEPVTTVTVKEESAPEEIIPIEIV ELPEETTVEETKTPEGKPKQRKVTKRIIKKRVGPKLETTQITTEQTDDDQPIISVHKTEE LIDDTTTPLEDLHKPEEAKPIEEAPEKVEVIQVRTETGDVKTIKTTKRVIKKKRGPKEEV TEITTIEKDDETPVTTVTVKEESAPEDTKPVEIVELPEETTVEETESPEGKPKHTKVTKR IIKKRVGPKLETTQIITEQTDDEQPIISVHKTEELIDDTTTPLEDLHKPEEAKAIEEAPE KVEVTQVRTETGDIKTIKTIKRVIKKKRGPKEEVTEITTIEKDDEEPVTTVTVKEESAPE EIIPIEIVELPEETTVEETKTPEGKPKQRKVTKRIIKKRVGPKLETTHITTEQADDEQPI ISVHKTEELIDDTTTPLAELHKPEKAKSIEEAPEKVEVIQVRTETGDVKTIKTTKRVIKK KRGPKEEVTEITTIEKDDEAPVTTVTVKEERAPEETKLVEIFELPEETTVEESKTPEGKP KQRKVTKRIIKKREGPKLETTQITTEQTDDEQPIISVHKTEELIDDTTTPLAELYKPEKA KPIEEAPEKVEVIQVRTETGDVKTIKTTKRVIKKKRGPKEEVTEITTIEKDDEAPVTTVT VKEESAPEDTKPVEIVELPEETTVEETETPEDLHKPEKAKPTEEAPEKVEVTQVRTETGD VKTIKTTKRVIKKKRGPKEEVTEITTIEKDGEEPVTTVTVKEESAPEETKPVEIIELPEE TTVEETETPEEELIDDTTTPLEDLHKPEEAKPVEEAPEKVEITQVRTETGDVKTVKTTKR VIKKKRGTKAEVTEITTIEKDGEEPVTTVTVKEESAPEETKPVEIVELPEETTVEETETP EGKPKHTTVKKRIIKKRVGPKLETTQITTEQTDDEQPIISVHKTEELIDDTTTPLADLHK PEEAKPVEEAPEKVEITQVRTETGDVKTIKTTKRVIKKKRGPKAEVTEITTIEKDDEEPV TTVTVKEESSPEETKPVEIVELPEETTVEETETPEGKPIQRKVTKRIIKKRVGPKLETTQ ITTEQTDDEQPIISVHKTEELIDDTTTPLEDLHKPEEAKPVEEAPEKVEVTQVRTETGDV KTIKTTKRVIKKKRGPKEEVTEITTIEKDDEGPVTTVTVKEESAPEDAKTVEIVELPEET TVEETETPEGKPKQRKVTKRIIKKRVGPKLETTQITTEQTDDEQPIISVHKTEELIDDTT TPLEDLHKPEEAKPVEEAPEKVEVTQVRTETGDVKTIKTTKRVIKKKRGPKEEVTEITTI EKDDEEPVTTVTVKEESAPEETKPVGPKLETTQITTEQTDDEQPIISVHKTEELIDDTTT PLEDLHKPEEAKPVEEAPEKVEVTQVRTETGDVKTIKTTKRVIKKKRGPKEEVTEITTIE KDDEEPVTTVTVKEESAPEETKPVEIVELPEETTVEETETPEGKPKHTTVKKRIIKKRVG PKLETTQITTEQTDDEQPIISVHKTEELIDDTTTPLEDLHKPEEAKPVEEAPEKVEVTQV RTETGDVKTIKTTKRVIKKKRGPKEEVTEITTIEKDDEEPVTTVTVKEESAPEETKPVEI VELPEETTVEETKTPEGKSKHTKVTKRIIKKRVGPKLETTQITTEQIDDEQPIISVHKTE ELIDDTTTPLEDLHKPEEAKSVEEAPEKVEVTQVRTETGDVKTIKTTKRVIKKKRGPKAE VTEITTIEKDGEEPVTTVTVKEESAPEETKPVEIVELPEETTVEETETPEGKPKHTTVKK RIIXKRVGPKLETTQITTEQTDDEQPIISVHKTEELIDDTTTPLEDLHKPEEAKPVEEAP EKVEVTQVRTETGDVKTIKTTKRVIKKKRGPKEEVTEITTIEKDDEEPVTTVTVKEESAP EETKPVEIVELPEETTVEETKTPEGKSKHTKVTKRIIKKRVGPKLETTQITTEQIDDEQP IISVHKTEELIDDTTTPLEDLHKPEEAKPVEEAPEKVEVTQVRTETGDVKTIKTTKRVIK KKRGPKEEVTEITTIEKDDEEPVTTVTVKEESAPEETKPSAPEETKPVEIVELPEETTVE ETKTPEGKPKHTKVTKRIIKKRVGPKLETTQITTEQIDDEQPIISVHKTEELIDDTTTPL EDLHKPEEAKPVEEAPEKVEVTQVHTETGDVKTIKTTKRVIKKKRGPKAEVTEITTIEKD GEEPVTTVTVKEESAPEETEPVEIVELPEETTVDENETPEGKPKHTTVKKRIIKKRRVGP KLETTQITTEQTDDEQPIISIHKTEELIDDTTTPLEDLHKPEEAKTVEEAPEKVEVTQVR TETGDVKTIKTTKRVIKKKRGPKEEITEITTIEKDDEAPVTTVTVKEESAPEETKPVEIV ELPEETTVEETETPEGKLKQTTVTKRIIKKRVGPKLETTHITTEQTDDEQPIISVHKTEE LIDDTTTPLTDLHKPDKAKPVEEAPEKVEVTQVRTQTGDVKTVKTTKRVIKNKKGPKEEV TEITTIEKDDEEPVTTVTVKEESAPEDSKPVEIVELPEETTVEETETPEGKLKQTTVTKR VIKRELTQTRQSQTGDVKTVKTTKRVIKNKKGPKEEVTEITTIEKDDEEPVTTVTVKEES APEDSKPVEIVELPEETTVEETETPEGKLKQTTVTKRIIKKRVGPKLETTHITTEQTDDE QPIISVHKTEELIDDTTTPLTDLHKPDKAKPVEEAPEKVEVTQVRTQTGDVKTVKTTKRV IKNKKGPKEKVTEITTIEKDDEEPVTTVTVKEESAPEDSKPVEIVELPEETTVDENETPE GKPKHTTVKKRIIKKRVGPKLETTHITTEQTDDEQPIISVHKTEELIDDTTTPLTDLHKP DKAKPVEEAPEKVEVTQVRTQTGDVKTVKTTKRVIKNKKGPKEEVTEITTIEKDDEEPVT TKSLNFLEETTVEETETPEGKLKQTTVTKRVIKKRVGPKLETTHITTEQTHDEQPIISVH KTEELIDDTTTPLTDLHKPDKAKPVEEAPEKVEVTQVRTQTGDVKTVKTTKRVIKNKKGP KEEVTEITTIEKDDEEPVTTVTVKEESAPEDSKPVEIVELPEETTVEETETPEGKLKQTT VTKRVIKKRVGPKLETTHITTEQTHDEQPIISVHKTEELIDDTTTPLTDLHKPDKAKPVE EAPEKVEVTQVRTQTGDVKTVKTTKRVIKNKKGPKEEVTEITTIEKDDEAPVTTVTVKEE SAPEDTKPVEIVELPEETTVEETETPGRKPKHTKVTKRVVKKRVGPKLETTQITTEQTDD EQPIISVHKTEELMDDTTTPLPDLHKPDKAKPVEEAPEKVEVAQVRTQTGDVKTVKTTKR VIKNKKGPKEEVTEITTIEKDDEEPVTTVTVKEESAPEDSKPVEIVELPEETTVEETETP EDTVVEPKKDFKEEERRPMVADIPHEDATPKKTDKRKAKLTPIKIERKELDIGKPQHAAS IEGPQFSTLKLKKTLVKPKEETKVVKLPKFQLKSRIKYIIDWPPPITTPVISFLGSVRQN GILSRNVKEAAKIKKRVYKAPILPEIEKIELEKPLFGYEDIVDAKKQTESENQDDELKPE DNFENEEIKEEEPEQFTISPRRPSIKKTDEIVGEVTIKKKLKPVRKSSVTLPEVTEPETV TFRPKSVKTKEDVEQEFNIHLDSYAEEEISMTSKVKLKPQRQPTFSEEADETSIKFYEDN ENEDTVPEIIEVIESDDDKEGDVNVSMPLKKLKQPSLEKSEVFDSSVTVSRPKSNEEILE IDQTIDLVLHKKPKYRIDDEEEITFDLKPQVEVLSNEDVSSKITIKQKPKVTVAEAATET SIQLIQEIEDDRQAEEIVLSEAESEQNVEMVIKRKPKKPVYEVSEVEELSVELKPKKVKD IAFEEEQLTISTKRKPKKPSQIQEADASMSIAREQEFPESPLDVRSGDTVFAVYSYVAET DEAISLVEGERLYILETTNQDWWFVRKHLTEEKGWVPAQYLMDEANYTLYLQKKLNEKID KLPVFEKPTSEEQAVAPIFTEKLRPKHTPDGSTVQFECQVEGYPRPQITWFRQTAIIKPS QDFQMYYDDDNVATLIIREVFPEDAGTFTCVAKNAAGFASSTTELIVEAPLSDHGSEMTI LSRKSLSRESSLADILEGIPPTFSKRPKAQYVDEGSQIFLECRLVAIPEPDIAWFFKGEE IMPDENISIATESDMHMYCSVLKISNVKKFQEGTYTVLAVNREGEASLPIVLKIKTGQKE QPQVIEPLKNITIREGESVVLSTQVVGNPQPTVNWYKNNKPVKSLTTKSDGDTHTVTIIK PRKGKDDGVYTLKAVNSEGTAETSAVITIEEPTEENAEPPLFINRFQEITVKEKGTIKLM AKVTGNPVPSITWYRNNKIITPSETVTQHFDGENIQLIISNVDSEIDSGDYKCVASNTAG KASHGARVTIDVDKVTFIKLLNKFYEIEEGKTIVLECQTSHTVSTKWFHNNKEISGMDHR EIIQEGRVHKLRIKKTKLTDVGDIKCVVKDQETNTQLIVHETVPEFVRKLQDFEVKERDV AILEVEVNSETADVYWEKDGDRIKPKKNKYELEKRGSIRKLYIRNTSVHDEGEYTCILRD DACTAEVTVVELPPEIISRLQDQKVSKGTKATFEIELTKGDALVQWFKNGSEIQFSNHIQ LTIDGKKQKLKIYDCQLDDAGEYACEVGNDRCTAKLTVEEPSIDFTLRLPEIVVVPANAD AYLTVKIPDETLDVTWFKKKTVIEDTEKFTLISDGVKRTLIIRKCTEEDQTEYSCLLLDA KCSTKLKVEEIEYPPRIISYDDEYRIKRGGDVTLLVQYEAVPQPNDEWVVNSKIIKKSKH TKPSIDSKSASLTIKKVEHTDAGTYKLRLENNCGVTDIDINLIVLDIPSAPGKPNVLETD NNSANVCWDEPTNKGNSEILCYIVEYQEINTVEWISIENVIKSQTTIKNLKTNSLYRFRV FAVNEVGVSESSEITDYVKIQKITARQPPSVEKPLKDVFAAPDEDIELTCIFGGVPQPKV TWYKDGKKLKTAKATYVNRVATLIVTTIESAEGEYKCIATNELGEVETSCKLEVQMKPII QVAEDEINQKHKVGEQWSVTATIKGIPKPNIMWFKNTMKLTKSNEINITIHEYITTIVIS ELKRTHSGKYIIEAQNKAGVTSFELSLNVFDKPSKPEGPVVMREISKESVTIEWKPPLDD GGIELTKYAIEKHEPETNQWVKVADVDKDIESYCIQRLNENCEYMFRVIAQNPVGFSEAL ESEPIVIKTALDVPSPPLGPLGLYGIDNESVTITWYPSEKNGGSPILDYSVEIKQEGKKW KHVATVTETTAKIKKLTMNTTYQFRICARNEIGTSLPYVSDEKITIGKSLSPPSRPLNFL LREITSRSVTLQWAAPESDGGSVITNYIIEYKTVKGKSWTKAITVGGTVYEHCIENIKEK EEFIFRISAENAVGISLPTESKSVKLEKHATVPSPPTAPLEIRMVGNNIVMTSWGTPEWD GGAPLLGYNIAIRDVTKTMWMEVGKVDAQTLKFNIRDLSENHTYMIRIFARNEIGLSEPL ESDEPFKVIPSEDSHADEEPGEQTEATEPTSFSTQTTTSWLREHNMDADIRSYARGSLLR RDEYFFRIWHYAKQLFK NT seq 48654 nt NT seq  +upstreamnt  +downstreamnt atggagaagcagtctagatggtcggagcagcgctctgagcagcgcgagcaggtggtgcag cagcaggagcgcgtgcagcgcaccgagcatcacttcacccgccagatgctcatgcagcac caagtggagagtactggcgaaagcctacccatcgctggaggaagacctggcgacccgtct ccaccaatctttgaacaaatcttcaagaatgcgagattcgcacagggtggcaatgccaaa tttgaaggaaaactcaggggaaatcctactcctgtcgtatcatggactagaaagaaagct cctcttgttgagtgtaataagtatagtatgagctataatgagcagactggagatgtatcc ttacttatcaaacaaataggaccaggtgacgagggagagtacacgtgcacggcccgcaat caatacggtgaggccatctgttcagtgtatatacaacccgaaggtgtccccatgccggca caccaagctagccagcagcagagttaccgacacgtgagcgaaaccgtcgaacataaatcg tacggtacgcaaggatattcctcggaacagtcccgaaaaatgcaaaaagtagcttatacc aacggcactgactattcgtccacagaagattttaaagtggatacgtttgaatatagactt ttaagagaagtatcttttagggagtctatcactaaaagatatgttggagagagcgacatt cacatcagcactgaaatagacaaatcactaggaccagtatcacctcctaaaatagcacaa aaaccgagaaattcgaaacttcaggagggcactgatgcacaatttcaagtgcagctttcc ggtaatcctagaccaagagtaacttggtttaagaatggtcagagattagtgaattccagt aaacatgaaatagtaacaacaaacaaccaaacaacgctgagagtaagaaatacacagaga tcagattctggccattacactctattggccgaaaaccccaacggatgtattgttacttct gcataccttgctgtagaatctcctcaagaaagttatgttcatgaccaaaaatcacagtac actattgacactcaacaagtaggaatagaagaaagagttgaaattaacgaaaaagctctc gctccgcaatttgtaagagtctgccaagaccgcgatgtaacggagggcaaaatgacgcga ttcgattgccgcgtcaccggcaggccttacccagaggtcacgtggttcattaacgacaga caaattcgagacgattataatcataagatattagtaaacgaatcaggtaatcatgcactt atgattacaaacgtcgatcttaatgatagtggtgtggtcacatgtgtcgcacgcaacaag agtggcgagacatcgttccagtgtcgattgaatgttattgaaaaagaacaagtagtagca cctaaatttgtagaacgattcagcactctgaatgttagagaaggcgagcctgttatactt aatgcccgcgcagtcggcacacccacgccacgtatcacatggcagaaggacggcgttcca attatacccaatccagagttacgaattaataccgacggtggagcctcgacgctggacatc ccgcgagccaaggcgtcggatgcggcatggtatcagtgcactgcccagaacgtcgcaggc tccacagcaactcgggctaggctttatgtggaagtacccaaagagcctgcgcctgaacaa aagcgccttcatttaccacggcctacgaaaataatcgaaccagagcctgcgccagggcca gaaatcatatacctaaggcatgtagaaagagcaagaccatatgttcctcctggtgaagaa gaccgagtttatcctccgcctcaatttatagtgccattaaaaagtgtcacgcagatggaa ggtggaaaaattcatttcgagacaaggattgatccggtcggtgatccatcaatgaagata gaatggttgaaaaatggacagagtattgaagcaagttcgcggtttacatccattttccga tttggctacatttctcttgacatgctcagtcttaatatacaagacagtggtgaatacaca tgtagagctgtcagtgcaactggtgtagctgaaactaaagcaacactgcacgtgacaccc agagctacaattgacagaactagtcaacacccagagactctacaatatctccaacataca gaagattactccaaatatcagcaccaagaatcaattgaagaacaagtttcacaaaggcca cagtttataaggccactgcaagatctaggtgaactacaagagggccgaaatgctcacttt gaagctcaattgattccagtcagtgactcaactatgcgagtggagtggtacaaggacggc agacccattacagctagctcgcgaatcacagcaatcttcaacttcggctacgtctccctt aacatcatgcacctacgggctgaagatgcaggttcgtatactgtgagagctgtaaataaa ttaggagaagctgttagtaccgcttcaattcgtgtagcagctaggagtactgtaacagga gatctaggtataccagaacaacgtagatatattgaaaagactgagcagttagaagcgtac cagcaacaacaacaccaaaagtactatcaagaagtaccagaaagcacccagggacctgaa ttcaaaactcctattaaggaccaaataaatattaaagaaggaggattcgctcatttcgaa gcgcggctggagcctataggagattcaacattacgagtagaatggctcaaagatggccgc cctgtcgaagcaagttcgaggataactacgttctttaattttggctatgtcgcacttact attaaatcagtgacagttcacgatgccggtcattacacctgtcgcgcatacaatgcactt ggtcaagcaagtaccagcgcaaatcttacaattgtgacgaagaaagatataattgcggaa tcacaacatcctggaggattggaaaaaatccagtatttagaagactccagcaggtattct cgccgcatggacgaagaagtaaaagttacacaaaagcccaggtttttgggaccacttaag ggcacaaataaaattgttgagggacaaggggcgcattttgaagccagggtagagccccaa agtgatttaactatgactgttgaatggtatttcaacggtaaacaaataacaagtgcaaac cgcatacaaacatatcacgattttggctacgtagcacttgacattgctaatgttcgggaa gaagactcgggagtatacacagtggttgcacgcaacgctgcaggagaagctcaactgagt gcttctatgagtgttgaaacgcgttcgagtattgatacttcaagcatacatcgaggactt tatgaaaaaactcgacaaattgaagaatctaagtttgttgagccatcatatcatatagaa gaaatttccaaatccaaaccagtttttgtacagcccctttcagatccaccaccagtgact gaaggcaaaaatattcaccttgaatgtagactagaacccatgggtgatccaactatgcgt gtggaatggttccataatggcagagctgttacggttggatctcgcttcaggacttactat gacttcggttttgtggcattagatattatacatgccacatccattgactcaggagaatac acagtacgtgctgtcaaccacttgggctctgcacacacgtcagctatggtacgcgttatc gaaagatcagacatcgttaccgacacacagaatgaacaggccattgaacagattcaaata ctagaagacgcagcccgaagaagtcgacaagttcaagaagatattactgtgatgcaagca ccacaattttcaagaccattacacaacatcgaaaccgtagaaggcactaatgtccatttg gaatgcagattgcaacccgtgggcgatcctaccatgaaggtggaatggttctgcaatgga aaacccataaaaaccgggcatagatttagaccagcttatgaatttgattacgtagcacta gatctattgagcgtatatccagaagattctggagtttacacatgtcaagctactaatcaa cttggagaagcagttacctcgtgcgctctccgcgtgattgctaaaaaggatttaatattt gaatctcaacacccatctggtcttgagaaaatacaatatttagaagatgcttcacgttac aagaagtctgaagttattgatgaagcaatcaatattaaaccgcgttttgttactaagcca aagtctatagaaaacgttattgaaggccagcatgtgcattttgaatgcaaactagaacct gtgaccgattccaatcttaaagtagaatggttcaaaaatggtcacccagtaacaattggt catcgtttccgacccattcatgactttggatatgtagccctggatatcatagacttaatt gccgaagactccggggtctacacttgcagagctacgaaccttgtgggcgccgacgaggtg agttgcaggctaacttgccgcggaacagcagatattattagagccacgcaaaatgaagct ggattagaacaaatccaagtattagaagacaggtcaaagtaccatagaactgactttgtt gatgaagtaactacacaagcacccatatttacaacgtctcttaaaaatgttgaaattaaa gagggacaacgtgcacatttcgagtgtaggcttatacctgtttccgatccaacgatgaaa gttgaatggtatcacaataaaacaccgctgaagagcggttcaagattcacagaaactaac aactttggttttgtagctttagacataatgtcttgtctacctgaagattctggtacttac acttgcagagctattaatgctctcggtgaggcagtcacttccggaattgctgtagtgcat tccaaaaaatctatatatttggaatcccatcatgaaggagctttgccaagacttaatcaa ttggaagatacatcaaggtaccagaaacatggtgtacaagatgaggtagtcactcaagca ccagttttcacaatgccaatgaaggacattcgagtagctgaaaaccaagcagcacacttt gaagctagacttattcctgtgggtgatccaaaattgagagttgaatggctacgtaacggt gtacccattgaagcatcaaatcgtttgacgacaatgcacgactttggttatgtcgctctg aacatgaaatacgttaatcctgaagattccggcacatacacatgccgcgccataaatgaa ttaggagaagcagttacatcatcaacactgtttgtgcaatctaaagcttcgcttcaactt gaatctcaacacgagacagctttagagaaaatacagctattggaagacagttcccgttac cgacgtaaagaagatgttgaggtagctgtcaatcaaccaccccgattcataactcaacta aatggcccttcgaaactcgtagaaggccagagcgcgcattatgaatgccgaattgaacca tacccagatccaaatatgcgtgttgagtggtacttcaatagcaaggtgttgcaaagtggt catcgctatcgtaccgcatacgattttggatttgcggctcttgatatacttacagtttat ggagaagactccggcgaatacacttgtaaggttataaataacttgggacaagctacatct tccatcaaattgaatgtgcaatccaaagaatccattatacgagatacgcagcatgaaagt gctcttgagaaaatacaatatcttgaagatgacagcaagtacaagcgtgtaattcgtgat gaaagctttgtggcagagaaacctcaattcggtaaacctatcaagaatgtccaagtcggt gaagggcaacctgtccatttggaagctactttaacaccagttaacgaccccacgatgagg gttgaatggtactgtaatggcagaccgatacagcaaggacaccgtttcaaaactacatac gacttcggatatgtggcattagatatcttatacgcgtatgctgaagacaccggtacttac atgtgcaaggccacaaatgctgtaggtgaagccgttactacaagctctgtgaatgtagat gccaaatctggactttaccttgacacattagatgagcagagattgaagaagattcaagag cttgagaaatacgaaagacctaaaccggctgaagtggaacaaccaggacaacgaccagta tttttgactgccctcacaagcctcgaacacttgaaagagggagatcgtgcccactttgag tgtagagttgaacccataaatgatcctgatctaactattgaatggttccttaacggacaa aaaataagagcgggtcacaggtacaggacgacacatgactttggttatgttgcattggac atattatacacttatgctgaagattctggaacatacatgtgtaaagcaactaataaactt ggcgaagcagttaatacatgcacgttgaaggttgcagggcatagaagtattattttggat actcaacatccaaatgggcttgagaagattaggcaattggaagcacaaggtcaccataca agaatagaagtggaagaaccaaagattagcccacctaggtttgttacggaactaaccgga actacccacgtatttgaaggtcaaacagcccacttcgaatgccaagttgaacctgtgcat gatcccaacttgcgtattgaattttaccacaatggcaaagccctgcaatctgcgtcacga ttccatatcacttttgattttggttacgtgtcattacatattcaacattgcattcctgaa gatgcaggtgaatactcagttaaagctataaatgctctcggccaatgtacgtcatccata tcaatgacagtaaccgcaaaaggtagtattatatcggaatcacaacgtccggaaggctta gaaaagatacgtgaattagaaccttctgaacccttcaagcgcccagaaatacctgaacca gtaacacgtcagagacctgtatttacacagccactacaaaacattgataacattcaagaa ggacaaactgcgcatttcgactgcagacttattccagtaggcgatccaactttgaagatc gaatggttcagaaacgaaaaattgatcgaagacagttccagaataacaaagactcatgac ttcggatatgtgtctatgacaattacgcatgtacgtgatgaagatcaaggagtctacatg tgcagagcatccaacttactaggagaggcagtcacaacagctgctatgaaaataaaaacc aaggcagctattcaaatggagacacaacatcctgagggcatgaaaaagattcaacaactt gaggaaccacaacgcaagaaacctgaagaacctgaacgtgaatttgaaaaaccaatcttc actcaagttcttacaggacctactgagttatgggaaggtcaacatgctcattacgaggcc cgtgttgtacctgtcggtgacccgagtctccgatttgagtggtacataaatggcgtggaa ttaaaaatgggttcaagattccgcaccactcacgattttggttttgtcacattggacatc aattcagtagttgcggaagacgctggattgtatatgtgtaaagccattaatagagctggc agcacagtatcctcgacatcgcttaaagttaagacaaaatctactattgttgatcaagct atgagacctgagtcttgggaacaaatccagcttaaagaagctgctatgaacaaggtgcca gagatgtttgtagacgctggtgtacaacaggcgccaatatttactacgcatctcaagagc ttagataagttcgttgaagggcaacatgtttatttagaagcccaagtagagccgcgaacc gatcctaacctgagaattgaatggttcaagaatggcgtgtctttaactactggagcaaga ctgaagagtacttttgatttcgggttagtgacgctgtctatcaatggattgagaattgat gattcgggtatttacacctgtaaagctaccaaccttattggagaagctgtttctacaaca tctatcaaagttgaagatcgtcattggttactcggtgactcacttcatccggaatcttta gacagaattggtgcattagaacaacctaaaccaggtaaacctgaagcacctgaacctgtt tatgaaattcctgtatttatttcgcatttgaataacataatatgtaaggaaggtgacaat atacacttcgaatgtaacgtcgaaccgtcgagggatcccacgcttaaaattgaatggttc tttaacaacaaacctttgccatcgggatcgagatataagagtacccatgacttcagctat gtgtcattagatattactcacacgtatgaagaagattctggtatctacacctgcaaagcg actaacagcaaaggatctgctactacttcgggatctcttcgatgcactggagaccgtaac atctaccttgatacacaacatccacaaggaaaggccggtctggaagcagtcgagcaagca gaagaagctaggctttctaaatctagacgagcttctgttcctgatgtcgaatatcctaaa cctgaatggattgttccagtggcccctgaacatcaactaattgaaggccaagctcttcac cttgaaggacaagtagagcctaagaatgaccctgatttgaaaattgaatggtactttaac ggtaaagtattggaacaaggttcaagattcaagcttacaagtgatttcggctttgtgact ttagatctcattgatgtgtatgaaagagatagtggaatttacacatgtaaagcatacaac aagagaggagaagcgttcacatcgtcgactgtatattgtactagcaaagagaatctaatt gaaagaacacaacatcctaaaggaaccgagggcttggaaaagatacagaatctggaagat tccttgcgtaaggagcctggacaaaagcctgatgatgataccggtaggcccccagaattc acttccgtgtttaaggatattgtcgatatcagtgaaggccagatcgctcattacgaagca tcacttatccctactggagatcaaagtatggtcatcgaatggttttacaatggcaaaacg attgaagcaagtcaccgtattcgaacagtatatgctttcggtatggttgttttagaaatt cttggaacaaaaactaccgattctggcgtatacgcttgccgtgctactaataggtggggt caagctgaaattagtgtcaaactagaatgtgtggataagagtaaaggtcaaaaaccaaga tttactacacatattcaaaacattgatggtcttaaagatggccaatctgcgcatttcgaa tgtacagtagtgcctgttgatgatccagacatgaaaattgaatggtatcataacggccaa cctttacgtcattcgacaagaataaaaactgtgtctgattttggcttcgtagttttagat atagcgtatactcagaatcatgatactggtgaatacgtttgtcgtgcttataataaatac 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