Mycolicibacterium smegmatis MC2 155: MSMEI_0421
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Entry
MSMEI_0421 CDS
T02191
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
msg
Mycolicibacterium smegmatis MC2 155
Pathway
msg00860
Porphyrin metabolism
msg01100
Metabolic pathways
msg01110
Biosynthesis of secondary metabolites
msg01120
Microbial metabolism in diverse environments
msg01240
Biosynthesis of cofactors
Module
msg_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
msg_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
msg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MSMEI_0421
Enzymes [BR:
msg01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MSMEI_0421
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Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
OmpA
Motif
Other DBs
NCBI-ProteinID:
AFP36902
UniProt:
I7FWE0
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Position
complement(509111..510268)
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AA seq
385 aa
AA seq
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MREPDWAPLTGFRVAVTSARRADELCALLRRRGATVTSAPAITMVPLPDDDELRAHTESL
ITDPPDIVVATTGIGLRGWIAAADGWGLAGELTEALGKARIVSRGPKATGALRAAGLPEE
WSPDSESSREVVRYLVEHGVDGRRIAVQLHGATDDWDPFPEFLDELRVAGAEVVPIRVYR
WHPAPPGGEFDQLVAGIAERRFDAVSFTSAPAVASVLMRATELGLTEQVVSALRTDVHAM
CVGPVTARPLVRLGIPTSAPERMRLGALARHITDELPLLQSRTLRVAGHLLEIRGTCVLV
DGVVKSLSPAGMATIRALAHRPGAVVSRFDLLGALPGSGTDTHAVETAVLRLRTALGDKS
IVSTVVKRGYRLAVDDTDTEMARAL
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgagcccgactgggcacccctcaccggattccgggtggcggtgacctccgcccga
cgagccgatgaactgtgcgccctgctgcgcaggaggggcgcgacggtgaccagcgcgccc
gcgatcaccatggtgccgctgcccgacgacgacgaactgcgggcacacaccgagtcgttg
atcaccgacccgcccgacatcgtcgtcgccaccaccggcatcgggttgcgggggtggatc
gccgcagccgacggctggggcctggccggcgagctgaccgaggcgctgggcaaggctcgc
atcgtgtccagggggccgaaggccacgggggcactgcgggccgccgggttgccggaggag
tggtcgccggactccgaatcctcccgcgaggtggtccgctacctcgtcgagcacggcgtc
gacggccggcgcatcgccgtgcaactccacggcgccaccgacgactgggatccgttccct
gagttcctcgacgagctgcgtgtcgcgggtgcagaggtggtgccgatccgtgtctaccgg
tggcatcccgccccaccgggcggcgagttcgaccaactcgtcgcaggcatcgccgaacgg
cgcttcgacgcagtcagtttcacctcggccccggccgtcgcctcggtgctgatgagagcc
accgagttgggactgaccgagcaggtggtctccgcgctgcgcaccgacgtccacgcgatg
tgcgtcggaccggtcacggcgcgtccgctcgtgcgcctcggcattcccacgtcggcgccc
gagcgcatgcggttgggcgcactggcccgccacatcaccgacgagttgcccctgctgcag
tcccgtacgttgcgggtcgcgggtcacctcctcgagatccgcgggacctgcgtgctggtg
gacggcgtggtcaagtcgctgtcccccgcgggtatggccaccatccgggcgctcgcgcac
cggcccggcgcggtggtgtcacgtttcgatctgctgggcgcgctgcccggcagcgggacc
gacacccacgccgtcgagaccgcggtgctgcgccttcgaactgcattgggagacaagagc
atcgtgtccaccgtggtgaaaaggggttatcggctggcggtcgacgacaccgacacagag
atggcacgcgcgttatga
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