Mycolicibacterium smegmatis MC2 155: MSMEI_0929
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Entry
MSMEI_0929 CDS
T02191
Name
(GenBank) Uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
msg
Mycolicibacterium smegmatis MC2 155
Pathway
msg00860
Porphyrin metabolism
msg01100
Metabolic pathways
msg01110
Biosynthesis of secondary metabolites
msg01120
Microbial metabolism in diverse environments
msg01240
Biosynthesis of cofactors
Module
msg_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
msg_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
msg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MSMEI_0929
Enzymes [BR:
msg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MSMEI_0929
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MSMEI_0929
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AFP37409
UniProt:
I7G4G9
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All DBs
Position
1032928..1034859
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AA seq
643 aa
AA seq
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MTRQVPLGGAESLTAVGGAESLATFGGVESVATMGGADSLTKVGGADAAVAVVGAAEGSV
GAAESPASDPQPRESSSRSRSRKVKPGRITFVGSGPGDPGLLTTRAQAVLAHAELVFTDP
DVPEAVLALVGTDLPPAAGPAPAKKNDKADKATDKSDKSDKADKADDAKSDDPAVIPGGP
EVRPALGDPAEVAKTLASEARHGYNVVRLIAGDPLSVDAVITEINALAKTHLTFEIVPGL
PDTTAVPTYAGLPLGSSHTVADVRGDVDWAALAAAPGPLILHATASHLPDAARTLIEHGL
VENTPAVVTANGTTCQQRSVETTLVGLTDKTVVEKPAGSELLGPLTGPLVVTIGKTVANR
AKLNWWESRALYGWTVLVPRTKDQAGEMSERLVTHGALPIEVPTIAVEPPRSPAQMERAV
KGLVDGRFQWVVFTSTNAVRAVWEKFNEFGLDARAFSGVKIACVGQATADKVRAFGINPE
LVPSGEQSSLGLLDEFPPYDEVFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRT
VRAAPPPAHTREMIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAIEF
GLRVDVQPETAAVGPLVEALAEHAARLRAEGALPPPRKKSRRR
NT seq
1932 nt
NT seq
+upstream
nt +downstream
nt
atgacccggcaggtccccctcggcggagccgagagtctgactgcagttggcggagccgag
agtctggccaccttcggcggagttgaaagcgtggccaccatgggcggagccgacagtctc
accaaggtgggcggtgccgacgctgcggttgcggtggtcggtgcggccgagggttcggtc
ggtgcggccgagagcccggcgtccgaccctcagccgcgtgagagctcgagccggtcgcgc
agccgcaaggtcaagcccggtcgcatcacgttcgtcggttcgggccccggtgacccgggc
ctgctgaccaccagggcgcaggccgtgctcgcgcatgccgagctggtcttcaccgatccc
gatgtgcccgaggcggtgctcgccctcgtcggcaccgatctgcccccggcggcgggtccg
gcgcccgccaagaagaacgacaaggccgacaaggccaccgacaagtcggacaagtccgac
aaggccgacaaggccgatgacgccaagtccgacgatccggcggtcatccccggcggaccc
gaggtgcgtcccgcgctcggcgacccggccgaggtcgccaagacgctcgcgtccgaggcg
cgccacggatacaacgtcgtgcgcctgatcgcgggtgacccgctgtcggtggatgccgtg
atcaccgagatcaacgcactggccaagacgcatctgaccttcgagatcgtcccgggtctg
cccgacaccaccgcggttccgacgtacgccggcctgccgctggggtcgtcgcacaccgtc
gccgacgtgcgtggcgacgtcgactgggccgcactggcggccgcgccggggccgctgatc
ctgcatgcgaccgcgtcgcacctgccggatgccgcccgcacgctcatcgagcacgggctc
gtcgagaacacgcccgcggtcgtcacggccaacggcaccacctgccagcagcgttcggtc
gagaccacgctggtggggctcaccgacaagaccgtggtggagaagcccgcgggcagcgag
ctgttgggcccgctgaccggaccgctggtggtcaccatcggcaagaccgtcgccaaccgc
gccaagctgaactggtgggagagccgcgccctgtacggctggaccgtgctggtgccgcgc
accaaggatcaggccggcgagatgagcgagcggctcgtcacgcacggcgccctgccgatc
gaggtgcccaccatcgccgtcgagccgccgcgcagcccggcgcagatggagcgcgcggtc
aagggcctggtcgacggccggttccagtgggtcgtgttcacctccaccaacgccgttcgc
gcggtgtgggagaagttcaacgagttcggtctggacgcccgcgcgttctccggcgtgaag
atcgcctgcgtggggcaggccaccgcggacaaggtgcgcgcgttcgggatcaatcccgaa
ctggtgccgtcgggcgagcagtcctcgctcggcctgctggatgaattcccgccctacgac
gaggttttcgacccggtcaaccgtgtgttgctgccgcgtgcggacatcgccaccgagacg
ctggccgagggtctgcgtgagcgtggctgggagatcgaggacgtcacggcgtaccgcacc
gtgcgtgcggccccgccgcctgcgcacacccgcgagatgatcaagaccggtggtttcgac
gcggtgtgcttcacgtcgagttcgaccgtgcgcaacctcgtcggcatcgcgggcaagccg
cacgcccgcaccatcgtggcctgcatcggaccgaaaaccgcagaaaccgcaatcgaattc
ggtctgcgcgtggatgtgcagcccgagacagccgcggtcggaccgctggtcgaggcgctc
gccgagcacgccgcccggttgcgcgccgagggtgcgctcccgccgccgcgcaagaagagc
cgccgcaggtaa
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