Mycolicibacterium smegmatis MC2 155: MSMEI_4512
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Entry
MSMEI_4512 CDS
T02191
Name
(GenBank) Folylpolyglutamate synthase protein FolC
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
msg
Mycolicibacterium smegmatis MC2 155
Pathway
msg00790
Folate biosynthesis
msg01100
Metabolic pathways
msg01240
Biosynthesis of cofactors
Module
msg_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
msg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MSMEI_4512
Enzymes [BR:
msg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MSMEI_4512
6.3.2.17 tetrahydrofolate synthase
MSMEI_4512
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Val_tRNA-synt_C
Motif
Other DBs
NCBI-ProteinID:
AFP40966
UniProt:
I7GCL2
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Position
complement(4715916..4717484)
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AA seq
522 aa
AA seq
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MAVAQKELATTTAKLGNEAFLSKAPAQVVDKIRGRQALASEEVERITARLAGLNDRSGPS
AGRGRRAAAGRAPPRPAVAGDQTGAEHHAHRGVARTARSPQRAYPSIHVAGTNGKTSVCR
IIDALLMALHRRTGRTTSPHLQSAVERISIDGKPISPAQYVATYTEIEPFVQLVDQQSEA
AGGPKMSKFEVLTAMAFAAFADAPIDVAVVEVGMGGRWDATNVVNAPVAVITPIGLDHTD
YLGDTIDAIAGEKAGIITRQPDDLVPTDTVAVIGKQDPAAMEVLLAEAVRADAAVAREDS
EFAVLGRQVAIGGQLLELQGLGGVYPEIFLPLHGEHQAHNAVLALAAVEAFFGAGADRQL
DVEAVRAGFAAVRSPGRMERMRNAPTVFIDAAHNPAGAAALAQTLQEEFDFRHLVGVVSV
MGDKDVDGILTALEPAFDQIVVTHNGSPRALDVESLAMRAEERFGPERVITATTLPDAIE
TATALVEEAGAESDSMSGAGMVITGSVVTAGAARTLFGRDPQ
NT seq
1569 nt
NT seq
+upstream
nt +downstream
nt
ttggcggtcgcccagaaggaactggccaccaccacggccaaactcggcaacgaggccttc
ctgtccaaggcgcccgcccaggtggtcgacaagatccggggcaggcaagccctggccagt
gaagaggtcgaacgcatcaccgcgcgcctggctggcctcaatgaccgatccggtcccagc
gccggacgaggtcgccgcgctgctgcaggtcgagcacctcctcgaccagcggtggccgga
gaccaaactggagccgagcaccacgcgcatcgcggcgttgctcgaactgctcggtcaccg
cagcgcgcgtacccgtcgatccacgtcgcgggcaccaacggcaagacctcggtgtgccgc
atcatcgacgcgttgctcatggcgctgcaccgcaggaccgggcgcaccaccagcccgcac
ctgcagtcggccgtcgaacgaatatccattgacggcaaaccgatctcgcccgcgcagtac
gtggccacctacaccgagatcgaaccgttcgtgcaactggtcgaccagcagtccgaggct
gcaggcggccccaagatgagcaagttcgaggtgctcacggcgatggccttcgcggcgttc
gccgatgcgccgatcgatgtcgcggtcgtcgaggtcggcatgggcgggcgctgggacgcg
accaacgtcgtcaacgccccggtcgcggtgatcaccccgatcggcctcgaccacaccgac
tacctgggcgacacgatcgacgcgatcgcgggggagaaggcgggcatcatcacccgccag
cccgacgacctggtgcccaccgacaccgtcgcggtgatcgggaagcaggaccccgccgcc
atggaggtgctgctggccgaggccgtacgcgccgacgccgcggtggcccgcgaggattcc
gagttcgcggtgctggggaggcaggtcgccatcggcggtcagctgctggaattgcagggc
ctcggtggcgtgtaccccgagatcttcctgccgctgcacggtgagcatcaggcgcacaac
gcggtcctcgcgctggccgcagtcgaggcgttcttcggcgccggggccgaccgtcagctc
gacgtcgaggccgtgcgcgccgggttcgcggccgtgcgcagccccggccggatggaacgg
atgcgcaacgcgccaacggtgttcatcgatgccgcgcacaacccggccggtgccgccgct
ctcgcgcagaccctgcaggaggagttcgacttccgccatctggtgggtgtggtgtcggtg
atgggtgacaaggacgtcgacggcatcctcaccgcgctggaacccgcgttcgaccagatc
gtggtcacgcacaacggctcgccgcgcgccctcgacgtcgaatcgctggcgatgcgcgcc
gaggaacgcttcggccctgaacgcgtgatcaccgccacgaccctgcccgacgccatcgag
accgcgacggccctcgtcgaggaagccggcgccgagtccgactcgatgtccggcgcgggc
atggtcatcaccggttcggtggtgaccgcgggcgcggccagaaccctcttcggacgggat
ccgcaatga
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