Mycolicibacterium smegmatis MC2 155: MSMEI_4595
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Entry
MSMEI_4595 CDS
T02191
Name
(GenBank) Pyruvate dehydrogenase E1 component (Alpha subunit) PdhA
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
msg
Mycolicibacterium smegmatis MC2 155
Pathway
msg00280
Valine, leucine and isoleucine degradation
msg00640
Propanoate metabolism
msg00785
Lipoic acid metabolism
msg01100
Metabolic pathways
msg01110
Biosynthesis of secondary metabolites
msg01210
2-Oxocarboxylic acid metabolism
Module
msg_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
msg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MSMEI_4595
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MSMEI_4595
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MSMEI_4595
Enzymes [BR:
msg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MSMEI_4595
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
AFP41046
UniProt:
A0R1D4
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Position
complement(4804072..4805184)
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AA seq
370 aa
AA seq
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MAMQYSSAPGYDTGFDPEPVQLVAADGSPSPDRPPSRYSRDLPPETLSWLYESMVVTRNL
DVEFVNLQRQGELALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMG
AVWRGKWHGGLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEG
DAHEAFNLATVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVL
ACYAVMSEAAERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYR
TYLQNIGVWTERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRD
QLLSELAKEA
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atggccatgcagtattcgtctgcgcccgggtacgacaccgggttcgaccccgaacctgtg
cagttggttgctgcggacggttcaccctcacctgacagacccccctcgcgctacagccgc
gacctccctccggagacgctgagctggctctacgaatcgatggtcgtgacgcgcaacctc
gacgtcgagttcgtcaacctgcaacgacagggtgagctggcgctgttcgcgtcgtgccgc
ggtcaggaggccgcgcagatcggcgcggcggcgtgcctgcgcaagaccgactggctgttc
ccgcagtaccgcgagatcggcgcgttcctgctgcgcggcatcacgccggcccagatgggt
gcggtgtggcgcggcaagtggcacggcgggctgtcgttcaccggcaagtgcgtcgcaccc
atcgcgatccccatcggcacccacggcctgcacgcggtcggcgcggcgatggccgcgcag
cggctcggcgaggactcggtgaccgtggcgttcctcggcgacggcgccaccagcgaaggc
gacgcgcacgaggccttcaacctggccacggtgttccgtgcgccgtgcgtgttcttcatc
cagaacaaccagtgggcgatctccgtgccggtcagccgccagcaggccggccccaccatc
gcccaccgcgcgatcggctacggcatgcccgggatccgtgtcgacggcaacgacgtgctc
gcctgctatgcggtgatgtccgaggccgccgagcgggcccgccgcggcgaggggccgacg
ctgatcgaggccgtcacctaccggatgggtccgcacaccacttccgacgatccgacccgc
taccgcccggccgaggaggtcgaggcgtgggcggcgcgcgatcccatcgcgcggtaccgc
acctacctgcagaacatcggggtgtggaccgagcgcctcgaagagcgggtggccgcgcgg
tcctcgcggctgtgcgccgagttgcgcgacgccatcgtcggtgcacccgacgtcgacccg
gccgagatgttcgacacggtctacgccgacatcacacccgaactggcgcgtcaacgtgat
cagttgctgtccgagttggcgaaggaggcctga
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