Mycobacterium shinjukuense: MSHI_07670
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Entry
MSHI_07670 CDS
T07415
Symbol
folC
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
mshj
Mycobacterium shinjukuense
Pathway
mshj00790
Folate biosynthesis
mshj01100
Metabolic pathways
mshj01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mshj00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MSHI_07670 (folC)
Enzymes [BR:
mshj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MSHI_07670 (folC)
6.3.2.17 tetrahydrofolate synthase
MSHI_07670 (folC)
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Gene cluster
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
BBX72861
UniProt:
A0A7I7MKN3
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Position
877328..878770
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AA seq
480 aa
AA seq
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MNSGSPAWWKHRPASNTGPTPDEIASLLQVEHLLDQRWPETRIEPSLTRIAALMDLLGSP
QLNYPSIHIAGTNGKTSVARMVDALVTALQQRTGRTTSPHLQSAVERISIDGLPISPAQY
VATYREIEPFVQMIDQQSSAAGGPAMSKFEVVTAMAFAAFADAPVDVAVVEVGLGGRWDA
TNVINAPVAVITPISVDHVDYLGQDITAIAGEKAGIVTRAAEGSPDTVAVIGRQTPEVMA
VLLAQAVAADAAVAREDSEFAVLGRRVAVGGQVLRLQGLGGVYSDIYLPLHGEHQAHNAA
VALAAVEGFFGAGAQRQLDVEAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGAAALA
QTLAAEFDFRMLVGVLSVMADKDVDGILAALEPVFDSVVVTHNGSARALDAESLALAARE
RFGPDRVTTAANLRDAIDAATALVDDAAAAGDACSGAGIVITGSVVTAGAARTLFGRDPE
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgaattccggatcgccggcctggtggaagcaccgtccggctagcaatacggggccgacg
ccggacgagattgcctctctgctgcaagtcgagcatctactcgaccagcgctggcccgag
acccgcatcgagcccagcttgacccgcatcgccgcactcatggacctgctgggctcaccg
caattgaactacccgtcgatccacatcgcgggcaccaacggcaagacctcggttgcgcgg
atggtcgacgcgttggtgaccgcgctacagcaacgcaccggccgaaccaccagcccacac
ctgcagtcggcggtggaacgcatcagcatcgacggcctgccgatcagcccggcccagtat
gtggcgacgtaccgggagatcgagccgttcgtccagatgatcgaccagcagtcatcggcc
gccggtgggccggccatgagcaagttcgaggtcgtcaccgcgatggcgttcgcggcgttc
gcggacgcacccgttgacgtcgccgtggtcgaggtcggtctgggcggacgttgggatgcc
accaatgtgatcaacgcgccggtggcggtcatcaccccaatcagcgtcgaccacgtcgac
tacctggggcaggacatcaccgcgatcgccggcgagaaggcgggcatcgtcacccgggcg
gccgagggttcgccagacaccgtcgccgtcatcgggcgtcagacaccggaggtgatggcg
gtcctgctggcccaggcggtcgccgccgacgccgcggtggcccgggaggattccgaattc
gcggtgctgggcagacgggtcgcggtcggcgggcaggtgctgcgactgcagggtctgggc
ggggtgtactccgacatctacctgccgctgcacggtgaacaccaggcgcacaacgcggcg
gtggcccttgccgccgtcgaggggtttttcggcgccggcgcgcagcgtcaacttgatgtc
gaggcggtccgggccggtttcgccgccgtcaccagccccgggcggctggagcgcatgcgc
agcgcgccaacggtgttcatcgatgccgcgcacaatccggccggggcggcggcactggcc
cagacgctggccgccgagttcgacttccggatgctggtcggtgtccttagcgtgatggcc
gacaaggacgtcgacggcatcctcgccgcgctcgagccggtgttcgattccgtcgtggtg
acccacaatgggtcggcgcgggcgctggacgcggaatcgctggcgttggcggcacgggag
cggttcggacccgaccgggtgaccaccgcagcgaacctgcgcgacgctatcgacgcggcg
accgcgctggtcgacgacgccgcggcagcaggtgacgcgtgctcgggcgccggaatcgtg
attaccggctcggtggtcaccgccggggccgcgcgcaccttgttcggtcgtgatcccgaa
tga
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