Mycobacterium simiae: MSIM_08190
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Entry
MSIM_08190 CDS
T07396
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
msim
Mycobacterium simiae
Pathway
msim00290
Valine, leucine and isoleucine biosynthesis
msim00660
C5-Branched dibasic acid metabolism
msim01100
Metabolic pathways
msim01110
Biosynthesis of secondary metabolites
msim01210
2-Oxocarboxylic acid metabolism
msim01230
Biosynthesis of amino acids
Module
msim_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
msim00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MSIM_08190 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MSIM_08190 (leuC)
Enzymes [BR:
msim01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MSIM_08190 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MSIM_08190 (leuC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Aconitase
BACC1_N
Motif
Other DBs
NCBI-ProteinID:
BBX39368
LinkDB
All DBs
Position
complement(894320..895810)
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AA seq
496 aa
AA seq
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MVGEPHEANRGEFTVGTEMQGPGDSRRRTLAEKVWEDHVVVSGSAAEGAGAPDLIYIDLH
LVHEVTSPQAFDGLRLAGRRVRRPDLTLATEDHNVPTVDIDKPIADPVSRTQVETLRANC
AEFGVRLHPMGDIEQGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVE
HVLATQTLPLRPFKTMAVNVDGELPPGVTAKDIILALIAKIGTGGGQGHVIEYRGSAIES
LSMEGRMTVCNMSIEAGARAGMVAPDQITFEFLRGRPHAPTGAQWDAAVQYWQRLRTDEG
AVFDTEVYLDAQSLTPFVTWGTNPGQGVPLGATVPDPELMTDDAERQAAEKALAYMDLRP
GMPMREIAVDTVFVGSCTNGRIEDLRVVADVLRGRKVAPGLRMLVVPGSMRVRSQAEAEG
LGEIFTAAGAEWRQAGCSMCLGMNPDQLAPGERCAATSNRNFEGRQGKGGRTHLVSPAVA
AATAIRGTLSAPADLN
NT seq
1491 nt
NT seq
+upstream
nt +downstream
nt
atggtcggcgagccgcacgaggcgaatcgaggcgagttcacggtgggaaccgaaatgcag
gggcccggcgacagccggcggcgcaccttggccgaaaaggtttgggaggaccacgtcgtg
gtatccgggtccgcagccgaaggcgccggcgcgcccgacttgatctatatcgacctgcat
ttggtgcacgaggtcaccagcccgcaggcgttcgacggtctgcgcctggccggtcgccgc
gtgcgccggccggatctgacgttggccaccgaggaccacaacgtgcccaccgtcgacatc
gacaagccgatcgccgacccggtatcgcgcactcaagtcgagacattgcgggcaaactgt
gccgaattcggtgtgcgcctgcatcccatgggcgatatcgagcagggcatcgtccatgtc
gtcgggccgcaattaggactcactcaaccgggaatgacgatcgtgtgtggggatagtcac
acgtccacgcacggcgcattcggcgcattggcaatgggcatcggtacttcggaggtcgag
catgtgctggcgactcagactttgccgctgcggccgttcaagacaatggcggtgaatgtc
gatggggagttgcctcccggcgtgacggccaaggacattattctcgcgctgatcgccaag
atcggtaccggcggcgggcagggccatgtcatcgaatatcgcggcagcgccatcgaatcg
ctatccatggaaggccgcatgacggtctgcaacatgagcatcgaagcaggcgcccgggcc
ggaatggtcgcaccggatcagatcacgttcgaattcctgcgtggccgaccgcacgcgccg
accggagcgcaatgggatgccgccgtgcagtactggcaacggctgcgtaccgacgagggc
gcagtcttcgacaccgaggtttacctggatgcgcaatcgttgactccgttcgtcacctgg
gggaccaacccgggccagggcgtgccgctgggtgccacggtgcccgatccggagttgatg
accgacgatgccgaacgacaggcggccgagaaagcattggcgtatatggaccttcggccg
ggtatgccgatgcgggaaatcgccgtcgacacggtgttcgtcggctcttgtaccaacggt
cgtatcgaagatttgcgggtggtggccgacgtgctgcgcggtcgcaaggtagctccggga
ctgcggatgctggtggtcccgggctcgatgcgggtgcgctcacaggccgaagccgaaggg
ctgggcgagattttcaccgctgccggcgctgaatggcgccaggcgggctgctcgatgtgc
ctgggcatgaaccccgatcagctcgcacccggcgagcggtgcgccgcgacctccaaccgc
aacttcgaagggcggcagggcaaaggcggccgtacacatttggtatcgccggcggtcgcg
gcggcaaccgcgatccgtggcacgttgtccgctccggccgacttgaactga
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