Mycobacterium simiae: MSIM_20080
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Entry
MSIM_20080 CDS
T07396
Name
(GenBank) transcriptional regulator
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
msim
Mycobacterium simiae
Pathway
msim00860
Porphyrin metabolism
msim01100
Metabolic pathways
msim01110
Biosynthesis of secondary metabolites
msim01120
Microbial metabolism in diverse environments
msim01240
Biosynthesis of cofactors
Module
msim_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
msim_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
msim00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MSIM_20080
Enzymes [BR:
msim01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MSIM_20080
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
TMEM213
Motif
Other DBs
NCBI-ProteinID:
BBX40557
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All DBs
Position
2139801..2141003
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AA seq
400 aa
AA seq
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MRQQSPGNTAETSRAYTGRMDRPDSAPLTGYRVAVTSSRRSEELCALLSRQGAEVSSAAA
INMIALPEDEELQSTTEAVIENPPDILVAHTGIGFRGWVAAAEGWGLANQLITSLSKARV
LARGPKATGALRAAGLHEEWSPKSESSQELLRYLLESGVSGKRIAVQLHGAADAWDPFPE
FIGGLRAAGADVVPIRVYRWKSTPMGGNFDQLVAGIARRQFDAVSFTSAPAAAAVLERSR
DLNIEGQVIEALRTEVHAMCVGPVTAQPLHRKGIPTSAPERMRLGALARHIAQKLPLLGS
STVRAAGHVVEIRGNCVLVDGSVQSLSGSGMAVLRALAQRPGDVVARGDLLRVLPGNSND
PHAVDTAVLRLRTALGDKNIVATVVKRGYRLAIDEQAGVS
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atgcgtcagcaatcgccgggtaacaccgccgaaacgtcgcgagcctacacaggtcgtatg
gaccggcccgactcggcaccgctcaccggttaccgggtagcggtgacgtcttcgcgccgg
tcggaagagctgtgtgcgttgttgagccggcaaggcgccgaagtctccagcgccgccgcg
atcaatatgatcgcgttgcccgaagatgaagagttacaaagcactaccgaagccgtcatc
gagaatcctcccgatattttggtggcccacaccggcatcggcttccgcggctgggtggcc
gccgctgagggctggggactagccaaccaactgatcacctcgttgtccaaggcgcgcgtg
ctggcgcggggtccgaaggcgaccggcgctctgcgtgccgccggcctgcacgaggagtgg
tcgcccaaatctgaatcctcccaagagctgctccggtaccttctcgagtccggcgtgtcc
ggcaagcggatcgcggtccagctgcacggcgctgccgatgcgtgggatccattcccggaa
ttcatcggcgggctgcgcgccgcgggtgccgacgtggtgcccatccgggtgtatcggtgg
aagtccaccccgatgggcggcaacttcgatcaactggtggccggcatcgcccgccggcaa
ttcgatgcggtcagctttacctcggcgcccgccgcggcggcggtcctggaacgcagccgc
gacttgaacatcgagggccaggtgatcgaggcgctacgcaccgaggtgcacgcgatgtgc
gtcggcccggtgacggcgcagccactgcaccgcaagggaattccgacctcggcgccggaa
cgaatgcggttgggtgccttggcccgtcacatcgcccagaagcttccgctgttgggatca
tcgaccgtgcgggccgccggtcacgtggtcgagatccgcggcaactgcgtcctcgtcgac
gggtcggtgcaatcgctgtccggatcggggatggcggtgctgcgcgcgctggcccagcgc
cccggtgacgtcgttgcccgcggcgacctgttacgggtgctgccgggcaacagcaacgat
ccgcacgcggtggacaccgcggtattgcgcctgcgaacagcgttgggcgacaagaacatt
gtcgcgacggtcgtcaagcgcggctaccggctggcaatcgatgagcaggcaggtgtgtcg
tga
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