Mycobacterium simiae: MSIM_34130
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Entry
MSIM_34130 CDS
T07396
Symbol
bkdA
Name
(GenBank) 2-oxoisovalerate dehydrogenase E1
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
msim
Mycobacterium simiae
Pathway
msim00280
Valine, leucine and isoleucine degradation
msim00640
Propanoate metabolism
msim00785
Lipoic acid metabolism
msim01100
Metabolic pathways
msim01110
Biosynthesis of secondary metabolites
msim01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
msim00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MSIM_34130 (bkdA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MSIM_34130 (bkdA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MSIM_34130 (bkdA)
Enzymes [BR:
msim01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MSIM_34130 (bkdA)
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GFIT
Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
DXP_synthase_N
Transketolase_C_1
Transketolase_N
PFOR_II
Gly-zipper_YMGG
Motif
Other DBs
NCBI-ProteinID:
BBX41962
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Position
complement(3599012..3600865)
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AA seq
617 aa
AA seq
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MSAGAALALSETDQLVTTYRGLGDVVAKGIDLPGYFAEILGRGTGLSKGKAGAMGIYDPD
HGIAWTTGIVGAGPLIANGIALAEAIKGSDRVVLVSFGDGATSIGYVHEAMNMAALWALP
VVFFCQNNAWAECTPVAGYTRSTRLSDRAAGYAMPGVTVDGTDPQAVYRAVTEAAERARS
GAGPSFVEAVAYRLQGHYFGDQMPYADPDELAAKRADPPFARYRRRLTDAGLADQADLDR
IDADLIAEIDTAFTAARDAEFPDTDELTRDVFAAHGVEIAAPVTDRAAIPEGETETLGLV
QAIHRTLDRALAADDSVVLLGEDIADPSGGMFKITAGLSTKYGAHRVRDTPIAESSIIGA
AVGAALGGLRPVAELMFVDFLGVAMDQIANHAAKIRYMSGGRQGAPLVIRAMVGTAAGPQ
HSQAFEAWAMHTPGIKVVWPSTAADAVGLLNACLAEQDPCLFIESMKLYYGGGKGPVPTA
DYVIPLGQADVKRAGTDVTICTYGSLVHAALDAADQLAAEDVSVEVVDLRSLVPLDLGTV
LDSVRKTRRLVVAHESVGFCGPGAEIAAAVGTELFGVLVSPIQRVAGAYTPVPRAATLEA
ACRPDAARLVEAVRRIA
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgtcggcgggggctgcactcgccctgtccgagacggatcagctggtcactacctatcgt
gggcttggcgacgtggtggccaagggcatcgacctgcccgggtacttcgccgagatcttg
ggccgcggcaccggcctgtcgaagggcaaggccggcgccatgggcatctacgaccccgac
cacgggatcgcgtggacgaccggcatcgtcggtgcgggcccgctgatcgcgaacgggatc
gcattggcggaggccatcaagggcagtgaccgcgtggtgctggtgagcttcggcgacggg
gcgaccagcatcggctacgtccacgaggcgatgaacatggcggcgctgtgggcgcttccg
gtggtgttcttctgccagaacaacgcgtgggccgaatgcacgccggtggcgggttatacc
cgctcgacgcgattgtcagaccgtgccgccgggtacgcgatgcctggcgtcacggtcgac
ggcacggacccgcaagcggtttaccgggccgtgaccgaggccgccgagcgcgcacggtcg
ggcgccggcccgtcgttcgtcgaagcggtcgcctaccgcctgcagggacactacttcggc
gaccagatgccctatgccgacccggacgaactggcggccaagcgcgccgacccgcccttc
gcccggtatcggcggcggctgaccgacgcgggtctggccgatcaggccgacctcgatcgc
atcgacgcggatctcattgccgagatcgacacagccttcaccgccgcgcgggacgccgag
ttccccgacaccgacgaactgacccgcgacgtgttcgccgcgcacggcgtcgagatcgcg
gcaccggtgaccgaccgtgccgcgattccggagggcgaaacggagaccctcggcctcgtg
caggcgattcaccgcactctggaccgcgcgttggcggccgacgattcggtcgtgctactc
ggcgaggacatcgccgacccgtcgggcggcatgttcaagatcaccgccgggttgtccacc
aagtacggcgcccaccgggtacgcgacactccgattgccgagtcctcgatcatcggcgct
gcagtgggcgcggccctgggcgggctccgccccgtggcggagctcatgttcgtggacttc
ctgggtgtggcaatggaccagatcgccaatcacgccgcgaagatccgctacatgtccggc
ggccgacagggcgcaccgctcgtcatccgcgcgatggtgggcacggcggccggcccgcaa
cactcccaagcgttcgaggcctgggcgatgcacacaccgggcatcaaggtggtgtggccc
agcaccgccgccgacgcggtcgggctgctcaatgcctgcctggcagagcaggatccatgc
ctgttcatcgagtcgatgaagctttactacggcggtggcaaggggcccgtgccgacggcc
gactacgtgatcccgctcggccaggccgacgtcaaacgcgccggcaccgacgtcacaata
tgcacctacggcagtctggtgcacgccgcgctcgatgccgccgaccagcttgccgccgag
gatgtttcggtagaggtggttgacctgcgcagcctggtgccgttggatctggggacggtc
ctcgactcggtacgtaagacccgtcgcctggtggtggcccacgagtccgtcggcttctgc
gggcccggcgccgaaatcgcagcggcggtcggcacagagctttttggcgtgctggtgagc
ccgattcagcgcgtagcgggagcgtacacgcccgtgcctcgggcagcgacattggaagcc
gcctgccgtccggacgccgcgcggcttgtcgaagcggtcaggagaatcgcgtga
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