Mycobacterium simiae: MSIM_41790
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Entry
MSIM_41790 CDS
T07396
Symbol
folC
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
msim
Mycobacterium simiae
Pathway
msim00790
Folate biosynthesis
msim01100
Metabolic pathways
msim01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
msim00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MSIM_41790 (folC)
Enzymes [BR:
msim01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MSIM_41790 (folC)
6.3.2.17 tetrahydrofolate synthase
MSIM_41790 (folC)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
BBX42728
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Position
4437585..4439051
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AA seq
488 aa
AA seq
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MTDSPDWLDHPGGAASAAPTPDEIASLLQVEHVLDQRWPETKIEPSLTRISALMDLLGSP
QLGYPSIHVAGTNGKTSVVRMIDALLTALHRRTGRTTSPHLQSAVERIAIDGKPISPAQY
VATYREIEPFVQMIDAQSQAAGGPAMSKFEVLVAMAFAAFADAPVEVAVVEVGMGGRWDA
TNVINAPVAVITPIGVDHVDYLGTDIAGIAGEKAGIITTAPDGAPDTVAVIARQAPEAME
VLLAQTVQSDAAVAREDSEFAVMGRQVAIGGQVLQLQGLGGVYSDIYLPLHGEHQAHNAA
VALAAVEAFFGAGAQRQLDVEAVRAGFAAVTSPGRLERMRSAPTVFIDAAHNPAGATALA
ETLNSEFDFRYLVGVLSVMADKDVDGILAALEPAFHSVVVTHNGSPRALDVESLALAAEQ
RFGPDRVLTAANLRDAIDVATALVDDAASEGLDGSDGNGGEFSGTGMVITGSVVTAGAAR
TLFGRDPQ
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atgaccgactcgccggactggctcgaccatcctgggggagccgccagtgcggccccgacg
ccggacgagatcgcgtccctgctgcaggtcgagcatgtgctcgatcagcgttggccggaa
acgaaaatcgaaccgagcctgacccgcatcagcgccctgatggacttactcggctcaccc
cagctgggttatccgtcgatacacgtcgcgggcactaacggcaaaacctcggtggtgcgg
atgatcgatgcgctgctgaccgcactgcaccggcgtaccggacgcaccaccagtccacat
ctgcagtcggccgtggaacgcatcgcaatcgacggaaagccgatcagcccagcgcaatac
gtggccacctaccgcgagatcgaaccgttcgtgcagatgatcgacgcgcagtcgcaagcc
gccggtggtccggcgatgagcaagttcgaggtcctggtcgcgatggcgttcgcggcgttc
gccgacgcgccggtcgaggtcgccgtggtcgaggtgggcatgggcggtcgttgggatgcc
actaacgtgatcaacgcgccggtcgcggtcatcaccccaatcggtgtcgaccatgtcgac
tatctcggcacggacatcgccgggatagccggcgagaaagccggcatcatcaccacggcc
cccgacggcgcccccgacaccgtcgcggtgatcgcccggcaggcgcccgaagccatggaa
gtacttctagcgcagactgttcagtccgatgcggcggtggcccgggaggactccgagttc
gcggtgatgggccgtcaggttgcgatcggcgggcaggtgctgcagttgcagggcctcggt
ggggtgtactccgacatctacctgccgctgcacggcgagcatcaggcgcacaatgccgcg
gtcgcgctggcggcggtcgaggcgttcttcggtgccggagcgcagcgccagctcgatgtc
gaggcggtgcgcgccggtttcgcggccgtcaccagccccggacgccttgagcggatgcgc
agtgccccaacggtttttattgacgctgcacacaacccggccggtgcgaccgcgctggcg
gagacgctgaacagtgaattcgacttccgctacctcgtcggggtccttagcgtgatggcc
gacaaggacgtcgacggcatcctcgcggccctggaaccggcctttcattcggtcgtggtg
acccacaacgggtcaccacgagcgttggacgtcgagtcgctggcgctggccgccgagcaa
cggttcggacctgaccgcgtgctgaccgccgcaaacctgcgggacgccatcgacgtggcc
accgcgctagtcgacgacgcggcctcggaagggttggacggctcggatggtaatggcggt
gagttctccggtaccggaatggtgatcaccggatcggtcgtcaccgccggggccgcgcgc
acgttgtttggtcgtgatccgcagtga
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