Methylocella silvestris: Msil_3481
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Entry
Msil_3481 CDS
T00802
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
msl
Methylocella silvestris
Pathway
msl00300
Lysine biosynthesis
msl00550
Peptidoglycan biosynthesis
msl01100
Metabolic pathways
msl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
msl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Msil_3481
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Msil_3481
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Msil_3481
Enzymes [BR:
msl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Msil_3481
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ACK52370
UniProt:
B8ETL8
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Position
3822981..3824477
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AA seq
498 aa
AA seq
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MSEIAIREASSSETARRSEPQEPLWTGLGLVAPLEARISGGAPRRGATGVSIDTRTLCPG
DLFFAISGFNSDGHDYVAAALEKGALAAVVDEAHAESLARLGPLYVVRDDVLAALERLGV
AARARTRARIAAVTGSVGKTSTKEALRLALSAAGRTHASVASYNNHWGVPLTLARMPRQT
EFGVFEIGMNHQGEITPLTRMVRPHVAIITTVAPVHMENFTGVEAIADAKAEIFAGLEPG
GVAILPADNPQFERLAAAAKRSAAGLVTSFGADKHAEARLLDVRLAADHSMVEADICGQL
LTYRLGAPGRHLAMNSLAVLLAAKALGVDPREAAQTLASFAAQPGRGQRLELQAPDGAFT
LIDESYNANPASMRAAFDLAGALAPPSPGRRVAVLGDMLELGSHAADMHAGLAQDLAANH
FDLVFAAGPLCKHLFDALPAAMRGEWRENAQMIAPAVAAAVHAGDLVIVKGSNGSKMSAV
VEALKHAASNGSNEGRTA
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atgagcgaaatagcgatccgcgaagcaagctcctccgaaactgcgcgccggagcgagccg
caggagccgctctggaccgggcttggccttgtcgcgccgctcgaagcgcggatcagcggc
ggcgcgcctcggcgcggcgcgacgggcgtctccatcgatacgcgcacgctttgcccgggc
gatctcttctttgcgatcagcggcttcaacagcgacgggcatgattatgtcgcggccgcg
ctggaaaagggcgccctcgccgccgtcgtcgacgaggctcatgcggagtcgcttgcgcgc
ctcggcccgctttatgtcgtgcgcgacgacgttctcgccgccctcgaacgcctcggcgtc
gccgccagggcgcggacgcgcgcgcgcatcgccgccgtcaccggctcggtgggcaagacc
tcgaccaaggaggcgttgcgcctcgccctttccgcggcggggcgaacccacgcctcggtc
gcctcttataataatcattggggggtgccgctgacgctcgcccgcatgccaaggcagaca
gagttcggcgtgttcgaaatcggcatgaaccatcaaggtgaaatcacgccgctgacgcgc
atggtgcgcccgcatgtggcgatcatcaccaccgtcgctccggtgcatatggaaaatttc
actggcgtcgaggcgatcgccgacgccaaggcggagattttcgcggggctggagccgggc
ggcgtcgccattctgccggccgacaatccgcagttcgagcggcttgccgctgcagcgaag
cgttcggcggcgggacttgtgacgagcttcggcgcggacaagcacgccgaggcccgtctt
ctggacgtgcgcctcgccgcggatcattccatggtcgaggccgatatttgcggacaattg
ctgacctatcgcctcggcgcaccggggcgacaccttgcgatgaattcgctcgccgtgctg
ctcgccgccaaggcgcttggcgtcgatccgcgcgaggcagcgcagacgctcgcctctttc
gccgcgcagcccggccgcggccagaggctggagcttcaggcgcccgatggagcctttacg
ctgatcgacgagagctataacgccaatccggcttcgatgcgcgccgccttcgatctcgcc
ggcgcgctggcgcctccttcgcccggacggcgcgtcgcggtccttggcgacatgctggaa
ctcgggtcccacgccgccgacatgcacgcggggctcgcgcaggatcttgccgccaatcat
ttcgacctcgtcttcgccgccgggccgctctgcaagcatctgttcgacgcgctgcccgcc
gcgatgcgaggggagtggcgcgaaaacgcgcagatgatcgcgccggccgtggcggccgcg
gttcatgccggcgatctcgtgatcgtcaagggatcgaacggctcgaagatgagcgccgtc
gtcgaagcgctgaaacacgccgcaagcaacggctcaaacgaggggcggaccgcctga
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