Mycobacterium spongiae: F6B93_03410
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Entry
F6B93_03410 CDS
T07689
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mspg
Mycobacterium spongiae
Pathway
mspg00860
Porphyrin metabolism
mspg01100
Metabolic pathways
mspg01110
Biosynthesis of secondary metabolites
mspg01120
Microbial metabolism in diverse environments
mspg01240
Biosynthesis of cofactors
Module
mspg_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mspg_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mspg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
F6B93_03410
Enzymes [BR:
mspg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
F6B93_03410
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
F6B93_03410
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QUR69562
UniProt:
A0A975K1E1
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Position
861569..863260
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AA seq
563 aa
AA seq
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MTRGRRPKPGRITFVGSGPGDPGLLTTRAATVLANAALVFTDPDVPGPVLALIGKDLPPV
SGPAPAKQDAGTVDAGGSGGGQASPTVMSGGPEIRPVLEESADVAKALAAEARAGADVVR
LVAGDPLSVDAVIAEVTAIARTSLHLEIVPGLAPTNAVPTYAGLPLRSSHTVADVRGDPK
DTDWEALAAAPGPLILQATGPQLADAARTLIEHELAESTPCVVTAQGTTCQQRSVETTLE
GLTDPAVLSGTEPPGFSSGSGGDTQNLPLVVTIGKTVASRTKLNWWESRALYGWTVLVPR
TKDQAGEMSERLTSYGALPLEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVR
AVWEKFGEFGLDARAFSGVKIACVGESTADRVRAFGISPELVPAGEQSSLGLLDDFPPYD
SIFDPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAATREMIKTGGFD
AVCFTSSSTVRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPDIAAVGPLVDAL
AEHAVRLRAEGALPPPRKKSRRR
NT seq
1692 nt
NT seq
+upstream
nt +downstream
nt
atgacgcgagggcgcaggccgaaaccgggccgcattacgttcgtgggctcaggtccgggt
gaccccggattgctgacaacacgggccgccacggtgctggcgaatgcggctctggtattc
accgaccccgacgtaccgggtccggttctggcgctgatcggcaaagatcttccgccggtg
tccggtccggcgccggccaagcaggatgccgggactgtcgatgcgggtggttcgggaggc
ggccaggcgtcaccgacggtgatgtctggtggtcccgagatccgcccggtgctggaggaa
tccgcggacgttgccaaggcgctggctgctgaggctcgtgcaggtgctgatgtggtgcgg
ctagtggccggcgatccgctctcggtggatgcggtgatcgccgaggtaaccgctatcgcg
cgcaccagcctgcacctggagatcgtgccaggcctggccccgacgaatgcggtgccgacg
tatgcgggacttccgctgcgttcgtcgcacacggttgccgacgtgcgcggcgatcccaag
gacaccgattgggaggcattggcggcagcgcccggtccgctgatcctgcaggcgactggg
ccgcagctggctgacgcggcccgcactctcatcgagcacgagctagctgagtccacgccg
tgcgtagttaccgcgcagggcaccacctgccagcagcgttcggtcgagacgaccctggag
ggactcaccgaccccgccgtgctcagcgggaccgagcctcctggattctcctccggaagt
ggcggggacacccagaatttgccgttggtggtcaccatcggcaagaccgtcgccagtcgg
acgaagctgaattggtgggagagccgcgcgctctacggctggaccgtgctggttccgcgc
accaaggaccaggctggcgagatgagcgagcggctgacgtcgtatggcgcgctgccgctc
gaggtgccgaccattgccgtagagccgccacgcagccccgcccaaatggagcgggccgtg
aagggtctcgtcgatggccgtttccagtgggtggtgttcacctctaccaacgcagtgcgg
gcggtgtgggagaagttcggtgaattcggtttggatgcccgcgcgttctccggggtgaag
atcgcgtgcgtgggcgagtccacggctgatcgggtccgtgcttttggaatcagccccgag
ctggtgcccgccggcgaacaatcctcgctgggtctgctcgacgatttcccgccctatgac
agcattttcgacccggtgaaccgggtgttgctgccgcgcgccgacatcgctaccgagacg
ctggccgagggtctgcgcgagcgcggctgggagatcgaggatgtcaccgcctaccggacc
gtgcgggctgcaccgcccccggcggccacccgcgaaatgatcaagacgggcgggttcgac
gcggtgtgcttcacctcgagctccacggtacgaaacctggtcggtatcgccggcaagccg
cacgcgcggaccatcatcgcttgcatcgggccgaaaaccgccgagacggccgccgaattc
ggtttgcgggtggatgtccagcccgacatcgccgcggtcgggccgttggttgacgccctg
gccgaacacgcagtccgattgcgcgccgagggcgcgttgcccccgccacgcaagaagagc
cgcaggcgctag
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