Mycobacterium spongiae: F6B93_06975
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Entry
F6B93_06975 CDS
T07689
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mspg
Mycobacterium spongiae
Pathway
mspg00290
Valine, leucine and isoleucine biosynthesis
mspg00660
C5-Branched dibasic acid metabolism
mspg01100
Metabolic pathways
mspg01110
Biosynthesis of secondary metabolites
mspg01210
2-Oxocarboxylic acid metabolism
mspg01230
Biosynthesis of amino acids
Module
mspg_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mspg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
F6B93_06975 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
F6B93_06975 (leuC)
Enzymes [BR:
mspg01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
F6B93_06975 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
F6B93_06975 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QUR66865
UniProt:
A0A975PW77
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All DBs
Position
1697165..1698604
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AA seq
479 aa
AA seq
DB search
MDETTAACGPRTMAEKIWDDHVVVSGEGAAQGGAPDLIYIDLHLVHEVTSPQAFDGLRLA
GRPVRRPDLTLATEDHNVPTVDIDKPIADPVSRIQVETLRRNCAEFGIRLHPMGDMEQGI
VHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMA
VNVDGQLPAGVTAKDIILALIAKIGTGGGQGHVIEYRGAAIESLSMEGRMTMCNMSIEAG
ARAGMVAPDQTTYEYLRNRRHAPTDAQWDAAIAYWQQLRTDAGAEFDTEVYLDASSLSPF
VTWGTNPGQGVPLSATVPDPELVTDEAERQAAEKALAYMDLRPGTPMRDISVDAVFVGSC
TNGRIEDLRVVAEVLRGRRLARGVRMLVVPGSMRVRAQAEAEGLGEVFTAAGAEWRHAGC
SMCLGMNPDQLSPGERCAATSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSAPTDLN
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atggacgagacaacggcggcatgtgggccgcgcacgatggccgagaagatttgggacgac
cacgtcgtggtgtccggcgagggcgctgcgcaaggcggggcgccagacttgatctacatc
gatctgcacttggtgcacgaggtcaccagtccacaagctttcgacggcctgcgccttgcc
gggcgcccagtgcgacggcccgacttgaccctcgctaccgaggatcacaacgtgcccacc
gttgacatcgacaagccgatcgctgacccggtgtcacgcatccaagtcgagaccttgcgg
aggaactgcgcagaattcggcatccgcctgcatccgatgggtgatatggagcagggcatc
gtccacgtggtcggacctcagttgggtctcacgcagccgggcatgacgattgtctgcggc
gacagccacacttctacccacggggcgttcggggcgctggctatgggaattggcacgtca
gaggtcgagcatgtgcttgctacccagacgctgccgctgcgaccgttcaagacgatggcg
gtcaatgtcgacggacagttgccggccggagtgaccgccaaggacatcattctcgccttg
atcgccaagatcggcaccggcggcggacagggtcatgtcatcgaatatcggggtgccgcc
atcgaatcgttgtcgatggaaggccggatgacgatgtgcaacatgagcatcgaagcaggc
gcgcgagcgggcatggtagccccggatcagacaacctacgagtacttgcgcaaccggcgg
cacgcgccgaccgatgcacaatgggacgcggcgatcgcatactggcaacaactgcgtacc
gacgctggtgccgaattcgacaccgaggtgtaccttgatgcgtcctccttgagtccgttc
gtcacgtggggtaccaaccccggccagggcgtgccgttgtcggccaccgtgccggatccc
gagctggtgaccgacgaggccgagcgccaggccgctgagaaagccttggcgtacatggac
cttcgccccggaaccccgatgcgcgacatcagcgtcgatgccgttttcgtcgggtcatgc
actaacggccggattgaagatctgcgggtggtggccgaggtgttgcgcggtcgccggctt
gcgcggggcgtgcggatgctggtcgttccggggtcgatgcgggtgcgtgctcaggccgaa
gccgaaggactcggcgaggtcttcacggctgctggcgccgaatggcggcacgcgggatgt
tcaatgtgcctgggcatgaatcccgatcagctgtcgcccggcgagcggtgtgccgcgact
tccaaccgcaacttcgaagggcgccagggcaagggtgggcgcacgcatttggtgtcccca
gcggtggcggctgccaccgcggtccgcggcacgctatccgcaccaactgacttgaactga
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