Microbacterium sufflavum: KV394_15760
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Entry
KV394_15760 CDS
T10224
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
msuf Microbacterium sufflavum
Pathway
msuf00300
Lysine biosynthesis
msuf00550
Peptidoglycan biosynthesis
msuf01100
Metabolic pathways
msuf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
msuf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
KV394_15760
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KV394_15760
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KV394_15760
Enzymes [BR:
msuf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
KV394_15760
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CbiA
GcnA_N
Motif
Other DBs
NCBI-ProteinID:
UPL12476
LinkDB
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Position
complement(3246993..3248405)
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AA seq
470 aa
AA seq
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MIALTLAEITAAVGGDLRVAGEHTPETVVDGLVDTDSRTMRPGSIFVAKPGAETDGHRFV
GAAVEAGAVLAIVEHPVDVPVSQIVVSDAVVALGELARAVVGRVRAGGGLRIVGITGSNG
KTTTKNFLARILADEGETVAPINSFNNEVGAPVTMLRVTHDTRYLVSEFGAAGPGSIARL
AGLVEPDLVVVLMVGLAHAGGFGGIEATAKAKSELVSAARVPGTAVLNADDPRVWAMREL
AEHRGLRVVGFGQSDAAEVRAHDIVVSASGTTCTIEVAGERRPLRLRVLGAHHVTNALAA
LTAAVQLGVAPADAIARLETVEIAERWRMQPMGNDRVRIINDAYNASPDSMAAALRTLAQ
ITGPDERTVAVLGAMSELGDSAGEEHDRIGLLAVRLNIRRIVVVGPEARRLYLAAVGEGS
WDSEAVHLPDQDAAFEYLRTELRDGDRVLVKSSNSVGLRHLGDRLGELFS
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgatcgccctgacgctcgctgagatcaccgccgctgtcggcggtgatctgcgtgtggcc
ggagagcacacccccgagaccgtcgtcgacggcctggtcgacaccgactcgcgcaccatg
cggccgggatcgatcttcgtggcgaagcccggcgcggagaccgatggacaccgtttcgtc
ggtgcggcggtcgaggccggtgccgtgctcgcgatcgtggagcatccggtcgacgtgccc
gtcagccagatcgtcgtctccgacgccgtggtcgccctcggcgagctggcgcgcgcggtc
gtgggccgcgtgcgcgcgggcggtgggctgcgtatcgtcggcatcaccgggtccaacggc
aagaccacgaccaagaacttcctcgcacgcatcctcgccgacgagggggagaccgtcgcc
ccgatcaactccttcaacaacgaggtcggtgcccccgtcacgatgctccgcgtgacccac
gacacccggtacctcgtgagcgagttcggggcggccggcccggggagcatcgcccgcctc
gccggactcgtcgaacctgacctcgtcgtcgtgctcatggtcgggctcgcgcacgcgggc
ggcttcggcggcatcgaggccacggccaaggcgaagtccgagctcgtgtcggcggcgcgg
gttccgggcaccgccgtgctcaacgcggacgacccccgggtgtgggcgatgcgcgagctc
gccgagcaccgcggccttcgcgtcgtcggcttcggtcagtccgacgcggccgaggttcgc
gcccacgacatcgtcgtgtccgcctccgggacgacctgcacgatcgaggtcgcgggggag
cgccgcccgctgcggctccgcgtgctcggcgctcatcacgtgaccaacgcgctggccgcc
ctcaccgcggccgtgcagctcggcgtagctccggccgacgcgatcgcccgcctggagacc
gtcgagatcgccgagcgctggcgcatgcagccgatgggcaacgatcgcgtgcgcatcatc
aacgacgcctacaacgcgagccccgactcgatggccgccgctctgcgcacgctcgcgcag
atcaccggcccggacgagcgcacggtcgccgtcctgggggccatgagtgagctgggcgac
agcgcgggcgaggagcacgaccgcatcggcctgctcgcggtgcgtctcaacatccgacgc
atcgtggtggtgggccctgaggcgcgccgcctctacctggccgcggtcggcgaaggctcc
tgggacagcgaggccgtgcatctgcccgaccaggatgcggcgttcgagtacctgcgcacg
gagctgcgcgacggcgaccgcgtgctggtgaagtcatccaactccgtgggcctgcggcat
ctcggcgatcgtctgggagaattgttctcgtga
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