Methanoculleus submarinus: OH143_12040
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Entry
OH143_12040 CDS
T08553
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
msum
Methanoculleus submarinus
Pathway
msum00230
Purine metabolism
msum00670
One carbon pool by folate
msum01100
Metabolic pathways
msum01110
Biosynthesis of secondary metabolites
Module
msum_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
msum00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
OH143_12040 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
OH143_12040 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
msum04147
]
OH143_12040 (purH)
Enzymes [BR:
msum01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
OH143_12040 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
OH143_12040 (purH)
Exosome [BR:
msum04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
OH143_12040 (purH)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
UYU18416
UniProt:
A0AAX3E910
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Position
2368816..2370300
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AA seq
494 aa
AA seq
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MKWALLSVWDKAGIVDLAKVLIEHDYGILSSGGTGAELARAGISFTDVSAYTGFPEMMHG
RVKTLHPKIHGGILGRRGIDDAVMQEHGIEPIDLVVVNLYPFEAMSGKGLSLEEIIEYID
IGGPAMVRAAAKNHKHVAVVADPGDYGMVADAVRRGGFSPEERLNLAAKAFARTAAYDAA
ITNHLTGIDRPFPDVFTVQFRNGRTLRYGENPHQAAAVYGDAGIAGEETLQGKEMSYNNY
LDVHAAVGLLREFEECAVVIVKHNNPCGVATGESPLETYIAAREVDPVSAYGSIVAMNRE
VGADVARELTGTFVEVVVAPSFTAEALEIMKAKENMRVLRLPGPVAQPEIRSIDGGVLVQ
RTEPYREDWRVVSEREPTAHEMRAMQLAWKVCRHTKSNAIIFADEDAVIGIGAGQMNRVE
SAEIAVRKSRRPLAGSAVASDAFLPFPDTMEVAAAAGATALVQPGGSIRDQEVIEAANRL
NIAMIFTGVRHFRH
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
atgaagtgggcactgctgtctgtctgggacaaggcaggcatcgtcgatctcgcaaaggtg
cttatcgagcacgattacgggatcctgagttccggcggcaccggggccgaactcgcgcgg
gcggggatttcgttcaccgacgtctccgcctacacgggctttcccgaaatgatgcacggt
cgggtcaagaccctccacccgaagatccacggggggatcctcggccgccgcggcatcgac
gatgccgtgatgcaggagcacggcatcgagccgatcgacctcgtggtggtgaacctctac
cccttcgaggcgatgagcggcaagggcctctctcttgaggagatcatcgagtacatcgat
atcggtggcccggcgatggtgcgtgcggcggcgaagaaccataagcacgtcgcggtcgtc
gcggatcccggcgactacgggatggtcgcggacgccgtccggcggggcgggttctctcct
gaagagcggttgaacctcgcggcaaaggcgttcgccaggacggccgcctacgacgccgcg
atcacgaaccaccttaccggcatcgaccggccgttccccgacgtcttcaccgtccagttc
aggaacggcaggacgctccgctacggcgagaacccgcaccaggcggctgccgtctacggc
gatgccggcatagcgggagaagagacgctccagggcaaggagatgtcctacaacaattac
ctcgatgtccacgccgcggtcggcctgctccgggagttcgaggagtgcgctgtggtcatc
gtcaagcacaacaacccctgcggcgtggcgaccggcgagagccccctcgagacctacatc
gccgcccgggaagtcgacccggtctcggcctacggctcgatcgtcgcgatgaaccgcgag
gtgggggcggacgtcgcccgggaactgacggggacgttcgtcgaggtcgtggtcgccccg
tcgtttacggcggaagccctcgagatcatgaaggcgaaggagaacatgcgggtgctccgg
ctgcccgggccggtggcgcagcccgagatacggagcatcgacggcggcgtcctggtccag
cggacagagccctaccgcgaggactggcgggtcgtgagcgagcgagagcccaccgcccac
gagatgcgggcgatgcagctcgcctggaaggtctgccggcacacgaagagcaacgccatc
atctttgcagacgaggacgccgtcatcgggatcggcgccgggcagatgaaccgggtcgag
tcggcggagatcgcggtcagaaagtcccggagaccccttgccgggtcggcggtcgcatcg
gacgccttcctgccgttccccgacacaatggaggtcgcggcggcggcgggcgcgacggcg
ctcgtccagccgggcggctcgatccgggatcaggaggtcatcgaggcggcgaaccggctc
aacatcgcgatgatcttcaccggcgtccggcacttccggcactga
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