Mycobacterium tuberculosis KZN 1435: TBMG_00560
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Entry
TBMG_00560 CDS
T00940
Name
(GenBank) bifunctional menaquinone biosynthesis protein menD
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
mtb
Mycobacterium tuberculosis KZN 1435
Pathway
mtb00130
Ubiquinone and other terpenoid-quinone biosynthesis
mtb01100
Metabolic pathways
mtb01110
Biosynthesis of secondary metabolites
mtb01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mtb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
TBMG_00560
Enzymes [BR:
mtb01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
TBMG_00560
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GFIT
Motif
Pfam:
TPP_enzyme_N
Motif
Other DBs
NCBI-ProteinID:
ACT23593
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Position
646559..648223
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AA seq
554 aa
AA seq
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MNPSTTQARVVVDELIRGGVRDVVLCPGSRNAPLAFALQDADRSGRIRLHVRIDERTAGY
LAIGLAIGAGAPVCVAMTSGTAVANLGPAVVEANYARVPLIVLSANRPYELLGTGANQTM
EQLGYFGTQVRASISLGLAEDAPERTSALNATWRSATCRVLAAATGARTANAGPVHFDIP
LREPLVPDPEPLGAVTPPGRPAGKPWTYTPPVTFDQPLDIDLSVDTVVISGHGAGVHPNL
AALPTVAEPTAPRSGDNPLHPLALPLLRPQQVIMLGRPTLHRPVSVLLADAEVPVFALTT
GPRWPDVSGNSQATGTRAVTTGAPRPAWLDRCAAMNRHAIAAVREQLAAHPLTTGLHVAA
AVSHALRPGDQLVLGASNPVRDVALAGLDTRGIRVRSNRGVAGIDGTVSTAIGAALAYEG
AHERTGSPDSPPRTIALIGDLTFVHDSSGLLIGPTEPIPRSLTIVVSNDNGGGIFELLEQ
GDPRFSDVSSRIFGTPHDVDVGALCRAYHVESRQIEVDELGPTLDQPGAGMRVLEVKADR
SSLRQLHAAIKAAL
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
gtgaacccctcgacgacacaggcgcgcgtcgtcgtcgacgaactgatccgcggcggcgtt
cgcgacgtggtgctgtgtccgggctcgcgcaatgcgccgctggccttcgcgctgcaggac
gccgaccggtccggccggatccggttgcacgttcgcatcgatgaacgcaccgccggctac
ctggccatcgggctggcaatcggggcgggcgcgccggtgtgtgtcgcgatgacatccggc
accgccgtggccaacctcggtccggcggtggtggaggcaaactacgctcgggtgccgctg
atcgtgctgtcagccaatcggccctacgagctgctgggcaccggcgccaaccagaccatg
gaacagctgggctatttcggcacccaggtgcgcgccagcatcagcctggggctggccgag
gacgcacccgagcggacctcggcgctcaacgcgacctggcgatcggctacgtgccgagtg
ttggcggccgccacgggtgctcgcaccgccaacgcgggccccgtgcacttcgacatcccg
ctgcgcgaaccgctggtgcccgatcccgagcccctcggcgcggtcaccccgccgggccgg
cctgctggcaagccgtggacctacacgccgccggtcaccttcgaccagccactggacatc
gacctgtcggtcgacaccgtggtcatctccgggcatggcgctggcgtgcaccccaacctc
gcggcgttgccgaccgtcgcagaaccgacggcgccgcggtccggggacaacccgttgcac
ccgctggcgctgccgctgctgcgccctcaacaggtgatcatgctgggccggccgacactg
catcgtccggtatcggtgctgctggccgacgcagaagtgccggtattcgcattgacaacc
ggtccacgctggccggatgtctcgggtaactcgcaggccaccggcacgcgggcggtcacc
accggcgcgccgcggcccgcgtggctggaccggtgtgcggcgatgaaccggcacgcgatc
gcggcggttcgggaacagctcgcggcgcacccgttgaccaccgggctgcatgtcgcggcg
gcggtgtcgcatgcgctgcggcccggtgaccagctggtgctcggggcatccaatccggtg
cgggatgtggcgttggccggtttggacacccgcggcatccgggtacggtccaaccgtggg
gtcgccggcatcgacggcaccgtgtccaccgcgatcggggcggccctagcttatgagggg
gctcacgagcgcaccggcagcccggactccccgccccgcaccatcgcactgatcggcgac
ctgacgttcgtgcacgacagctccgggctgttgatcgggccgaccgaaccgataccgcgg
tcattgaccatcgtggtgtctaatgacaacggcggcggcatcttcgaattgctcgagcag
ggtgatcccaggttctccgacgtgtcatcgcgaatcttcggcaccccacacgacgtcgat
gtgggcgcattgtgccgcgcctaccacgtggaatctcgccagatcgaggtcgacgaactc
ggaccgaccctcgatcaacccggtgccggcatgcgcgtgctcgaggtcaaggccgaccgg
tcgtcgttgcgacaattgcacgccgccatcaaggcggctctgtga
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