Mycobacterium tuberculosis CDC1551: MT2572
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Entry
MT2572 CDS
T00053
Name
(GenBank) 2-oxoisovalerate dehydrogenase E1 component, alpha subunit, putative
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mtc
Mycobacterium tuberculosis CDC1551
Pathway
mtc00280
Valine, leucine and isoleucine degradation
mtc00640
Propanoate metabolism
mtc00785
Lipoic acid metabolism
mtc01100
Metabolic pathways
mtc01110
Biosynthesis of secondary metabolites
mtc01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mtc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MT2572
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MT2572
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MT2572
Enzymes [BR:
mtc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MT2572
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
MCD
Motif
Other DBs
NCBI-ProteinID:
AAK46876
UniProt:
P9WIS2
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All DBs
Position
complement(2806481..2807584)
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AA seq
367 aa
AA seq
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MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE
FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW
RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH
EALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY
AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL
QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR
AELARTD
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atgggggagggttctcggaggccatctgggatgttgatgtctgtcgatcttgagccggtg
caactcgtcggcccggacggtacgccgacggccgaacgccgctaccaccgtgaccttcct
gaggaaacgctgcgttggctctacgagatgatggtggtcacccgcgagctggataccgaa
ttcgtcaatctgcagcgccagggggagctggcgttgtacacgccctgtcgcgggcaggaa
gccgcgcaggtgggtgcggcggcttgcctacgcaaaaccgactggttgttcccccaatac
cgagaattgggcgtctacctagtgcgtggcatcccgcctggacatgttggggtcgcgtgg
cgtggaacctggcacggcgggctgcaattcaccacgaagtgctgtgcaccgatgtcggtt
cccatcggcacccagaccttgcacgcggtgggcgcggcgatggccgcgcaacgcctggac
gaggactccgtgacggtggcctttctgggcgacggcgccaccagcgagggcgacgtacat
gaggcgctcaatttcgcggcggtgttcaccacaccgtgcgtgttctacgtgcagaacaac
cagtgggcaatctcgatgccggtatccaggcagaccgccgcaccatctatcgcgcacaag
gcgattggctacgggatgccaggcatccgggtggacggcaacgacgtgctggcatgctat
gcggtgatggccgaagctgccgctcgggctcgggccggcgacggtccaacgctgatcgag
gcggtcacttaccgtcttggtccgcacaccaccgccgatgatccaacccggtaccgcagc
caggaggaggtggaccgctgggcgacgctggacccgattccgcgctatcgcacttactta
caagatcagggcctgtggtcgcaacgcctcgaggaacaggtgacggctcgggcaaaacac
gtgcggtccgagctacgcgacgcggtctttgatgcgcctgacttcgacgtcgatgaggtg
ttcaccacggtgtacgccgaaatcacacccgggttgcaggcgcagcgcgaacagctgcgt
gccgaactggcgcggactgactga
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