Mycobacterium tuberculosis CDC1551: MT3083
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Entry
MT3083 CDS
T00053
Symbol
ilvB
Name
(GenBank) acetolactate synthase, large subunit
KO
K01652
acetolactate synthase I/II/III large subunit [EC:
2.2.1.6
]
Organism
mtc
Mycobacterium tuberculosis CDC1551
Pathway
mtc00290
Valine, leucine and isoleucine biosynthesis
mtc00650
Butanoate metabolism
mtc00660
C5-Branched dibasic acid metabolism
mtc00770
Pantothenate and CoA biosynthesis
mtc01100
Metabolic pathways
mtc01110
Biosynthesis of secondary metabolites
mtc01210
2-Oxocarboxylic acid metabolism
mtc01230
Biosynthesis of amino acids
Module
mtc_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
mtc_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
mtc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
MT3083 (ilvB)
00660 C5-Branched dibasic acid metabolism
MT3083 (ilvB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MT3083 (ilvB)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
MT3083 (ilvB)
Enzymes [BR:
mtc01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.6 acetolactate synthase
MT3083 (ilvB)
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Motif
Pfam:
TPP_enzyme_M
TPP_enzyme_C
TPP_enzyme_N
CO_dh
DUF5612
Motif
Other DBs
NCBI-ProteinID:
AAK47412
UniProt:
P9WG40
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Position
complement(3355506..3357362)
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AA seq
618 aa
AA seq
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MSAPTKPHSPTFKPEPHSAANEPKHPAARPKHVALQQLTGAQAVIRSLEELGVDVIFGIP
GGAVLPVYDPLFDSKKLRHVLVRHEQGAGHAASGYAHVTGRVGVCMATSGPGXTNLVTPL
ADAQMDSIPVVAITGQVGRGLIGTDAFQEADISGITMPITKHNFLVRSGDDIPRVLAEAF
HIAASGRPGAVLVDIPKDVLQGQCTFSWPPRMELPGYKPNTKPHSRQVREAAKLIAAARK
PVLYVGGGVIRGEATEQLRELAELTGIPVVTTLMARGAFPDSHRQNLXMPGMHGTVAAVA
ALQRSDLLIALGTRFDDRVTGKLDSFAPEAKVIHADIDPAEIGKNRHADVPIVGDVKAVI
TELIAMLRHHHIPGTIEMADWWAYLNGVRKTYPLSYGPQSDGSLSPEYVIEKLGEIAGPD
AVFVAGVGQHQMWAAQFIRYEKPRSWLNSGGLGTMGFAIPAAMGAKIALPGTEVWAIDGD
GCFQMTNQELATCAVEGIPVKVALINNGNLGMVRQWQSLFYAERYSQTDLATHSHRIPDF
VKLAEALGCVGLRCEREEDVVDVINQARAINDCPVVIDFIVGADAQVWPMVAAGTSNDEI
QAARGIRPLFDDITEGHA
NT seq
1857 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgcaccaaccaagccacactcaccgacattcaagccagagccacacagcgcggcg
aatgagccaaagcacccggcggctcgtccgaaacatgttgcactgcagcagcttaccggt
gcacaggcggtcatccggtcgctggaggaactcggcgtcgacgtcattttcgggattccg
ggcggtgcggtgctgccggtgtatgacccgctgttcgactcgaaaaagctgcgccacgtg
ctggtccgccacgaacagggcgccgggcatgccgccagcggctacgcgcacgtcaccggc
cgggtgggcgtgtgcatggcaacgtcgggtcccggarcgaccaacctggtgaccccgctg
gccgacgcgcagatggactcgatcccggtggtcgctatcaccggtcaggtcgggcggggg
ctgatcggcaccgacgccttccaggaggccgacatctcgggcatcacgatgccgatcacc
aagcacaactttctggtccgctccggtgacgacattccgcgggtgctggccgaggccttc
cacatcgcggcctccggccgtccgggcgcggtgctggtcgacatccccaaggacgtgctg
cagggccagtgcacgttcagctggccgccgcggatggagctgcccggctacaagcccaac
accaaaccgcacagccggcaggtccgcgaggccgccaagctgatcgcggccgcgcgcaag
ccggtgctgtatgtcggcggcggcgtcatccgcggtgaggccaccgagcagctccgggag
ctggccgagctgaccggcatcccggtggtcaccacgctgatggcccgcggcgcgtttccc
gacagccaccggcaaaacctcngcatgcccggcatgcacggcacggtggccgccgtggcg
gcgctgcagcgcagcgacctgctgatcgcgctgggtacccgcttcgacgaccgggtgacc
ggcaagctcgactcgttcgcgccggaagccaaggtcatccacgccgacatcgacccggcc
gagatcggcaagaaccgccacgccgacgtgcccatcgtcggtgacgtcaaggccgtcatc
accgaactgatcgcgatgctgcgccaccaccacattcccggcaccatcgagatggccgac
tggtgggcatacctgaacggtgtgcgcaagacctatccgctgagctatgggccgcagagc
gacggcagcctgagcccggaatacgtgatcgaaaagctcggcgagatcgccgggccggac
gccgtcttcgtcgccggcgtcggccagcaccagatgtgggccgcgcagttcatcagatac
gaaaagccgcgcagctggctgaactccggcggtctgggcaccatggggtttgccatcccg
gcggccatgggcgccaagatcgccctccccggcaccgaggtctgggcgatcgacggcgac
ggttgcttccagatgaccaaccaggagctggccacctgcgcggtcgagggcataccggtc
aaggtggcgctgatcaacaacggcaacctgggcatggtgcggcagtggcagagcctgttc
tatgccgagcggtactcgcagaccgacctggccactcattcgcaccgcatccccgacttc
gtgaaactggccgaggccttggggtgtgtggggttgcggtgcgagcgggaagaggacgtc
gtcgacgtcatcaaccaggcgcgggcgatcaacgactgcccggtggtgatcgacttcatc
gtcggtgccgacgcgcaagtgtggccgatggtggccgcgggcaccagcaatgacgagatc
caggccgcccgcggcattcgccccctgttcgacgacatcaccgaaggccacgcctga
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