Micromonospora terminaliae: GCE86_22765
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Entry
GCE86_22765 CDS
T06293
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mtem
Micromonospora terminaliae
Pathway
mtem00860
Porphyrin metabolism
mtem01100
Metabolic pathways
mtem01110
Biosynthesis of secondary metabolites
mtem01120
Microbial metabolism in diverse environments
mtem01240
Biosynthesis of cofactors
Module
mtem_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mtem_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mtem00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
GCE86_22765
Enzymes [BR:
mtem01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
GCE86_22765
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
GCE86_22765
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
PqqF-like_C_4
Motif
Other DBs
NCBI-ProteinID:
QGL49598
LinkDB
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Position
complement(4961156..4962736)
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AA seq
526 aa
AA seq
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MTRTRKPVGRIAFVGAGPGDPGLLTRRALDALVDADQVVYDRGVPESLLEHVRAQARSDA
EFSPAEGVPGDVAKVLISAARSGQNAVHLVAGDPFGHDSVVKEVQAVARTAAHFEVVPGV
GQAEGVATYAGVPLPGVRTAADVEDVTTLDFDALAAAVARGSLAVAVDAGDLAAIRDGLL
AAGVDGATPVAVTGDGTGETQYTTTSTVDSFVAAALGFTGRVVLTVGAGVSDRDKLSWWE
NRPLYGWKVLVPRTKEQAGAMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVDGR
YAWVIFTSVNAVRAVWEKFAEHGLDARHFGGVKIACIGEATAEAVRAFGIQPELIPSGEQ
SSEGLLAEFSPHDEILDPVGRVLLPRADIATETLAAGLTERGWEVDDVTAYRTVRAAPPP
AEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETATEFGLRVDVQ
PPHASVPDLVEALAAYAVELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atgacccgcacccgtaagcccgtaggccggatcgcgttcgtcggggccggccccggcgac
ccgggcctgctgacccgccgggcgctggacgccctggtcgacgccgaccaggtggtgtac
gaccggggagtccccgagtcgctgctggagcacgtccgcgcccaggccaggtccgacgcc
gagttcagccccgccgagggtgtgccgggggacgtggcgaaggtgctgatctccgcggcc
cggtccggccagaacgccgtgcacctggtcgccggtgacccgttcggccacgactcggtg
gtcaaggaggtgcaggcggtcgcgcgtaccgccgcgcacttcgaggtggtgccgggcgtc
ggccaggccgagggcgtggccacctacgccggcgtgccgctgccgggggtacgcaccgcc
gccgacgtcgaggacgtcaccacgctggacttcgacgcgctggccgcggccgtggcccgg
ggctccctggccgtcgcggtggacgccggtgacctggccgccatccgggacggcctgctg
gccgccggcgtggacggcgccacccccgtcgcggtgaccggcgacggcacgggcgagacg
cagtacaccaccacgtcgaccgtggactccttcgtcgcggcggcgctcggcttcaccggc
cgggtcgtgctcaccgtgggcgcgggcgtctccgaccgcgacaagctgagctggtgggag
aaccggccgctgtacggctggaaggtgctcgtaccccggaccaaggagcaggccggcgcc
atgagcgcgcggctgcgggcgtacggggcgatcccgtgcgaggtgccgaccatcgcggtc
gagccgccgcgcacccccgcccagatggagcgggcggtcaagggcctggtcgacggccgg
tacgcctgggtgatcttcacctcggtgaacgcggtccgggcggtctgggagaagttcgcc
gagcacggcctggacgcccgccacttcggcggcgtcaagatcgcctgcatcggcgaggcc
accgccgaggcggtccgcgccttcggcatccagccggagctgatcccctccggggagcag
tcctccgagggcctgctggccgagttctcgccgcacgacgagatcctcgacccggtcggc
cgggtgctgctgccgcgcgccgacatcgccaccgagaccctggccgccgggctcaccgag
cggggctgggaggtcgacgacgtgaccgcgtaccggaccgtccgggccgcgccgccgccc
gccgagatccgcgacgccatcaagtcgggcgggttcgacgcggtcctcttcacgtcgtcc
tcgaccgtccggaacctggtcgggatcgccgggaagccgcacgcgcgtaccgttgttgcg
gttatcgggcccaagacggcggagaccgctacggagttcggcctgcgggtcgacgtgcag
ccgccgcacgcctcggtgcccgacctggtggaggcgctcgccgcctacgccgtcgagctg
cgcgagaagctcgccgccatgccggccaagcagcgccggggctcgaaggtgcagggcccg
accgccctgaggttccgctga
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