Mycobacterium tuberculosis F11: TBFG_12187
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Entry
TBFG_12187 CDS
T00545
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase murF
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mtf
Mycobacterium tuberculosis F11
Pathway
mtf00300
Lysine biosynthesis
mtf00550
Peptidoglycan biosynthesis
mtf01100
Metabolic pathways
mtf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mtf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TBFG_12187
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TBFG_12187
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TBFG_12187
Enzymes [BR:
mtf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TBFG_12187
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABR06518
LinkDB
All DBs
Position
complement(2431033..2432565)
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AA seq
510 aa
AA seq
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MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH
AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV
AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR
TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH
SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE
VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD
AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS
RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD
VVLVKASNAAGLGAVADALVADDTCGSVRP
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagctgaccgtcgcgcagatcgccgagatcgtcgggggcgcagtggccgatatc
tccccgcaagacgccgcgcaccgccgcgtcaccgggaccgtcgagttcgactcgcgcgcc
atcggcccgggcgggctgttcctcgccctgccgggggcgcgcgccgacggccacgaccat
gccgcgtcggcggtagccgcgggcgccgccgtcgtgctggccgcccgcccggtgggggtg
ccggccatcgtggttccgccagtggccgcgccgaacgtattggccggcgtcctcgagcac
gacaacgacgggtcgggggcggcggtgctggccgcgctggccaagctggccaccgcggtg
gccgcgcagttggtggccggcgggctcaccatcatcgggatcaccggctcgtcgggcaag
acgtcgaccaaggacctgatggccgccgtgctggccccgctgggggaggtggtggccccg
cccggatcgttcaacaacgagctgggtcacccgtggacggtgctgcgcgcgacgcggcgc
accgactacctgattttggagatggcggcacgccatcacggcaacatcgccgcgctcgcc
gagatcgcgcccccgtcgatcggagtcgtgctcaacgtcggcaccgcacatttgggtgag
ttcggctcccgcgaggtcatcgcacagaccaaagccgaactgccgcaggctgttccgcat
tccggagcggtcgtcctcaacgctgatgaccccgcggtggcggcgatggccaagctgacc
gcggcccgggtggtgcgggtcagccgggacaacaccggtgacgtttgggcggggccggtg
tcgctggacgaattggccaggccgcgctttacgctgcatgcccacgatgcccaagccgag
gtccgactcggggtctgcggcgaccaccaggtcactaacgcgctgtgcgccgcggcggtc
gcgctggagtgtggggccagcgttgaacaggtcgcggccgcgctgaccgcggcgccgccg
gtgtcgcggcatcggatgcaggtgaccacccgcggcgacggggtgacggtgatcgacgac
gcctacaacgccaaccccgactccatgcgggccgggctgcaggcgctggcctggatcgcg
caccaacccgaggccacccgccgcagctgggcggtgctgggtgagatggccgagctgggt
gaggacgcgatagccgagcacgatcgcatcggccggctcgcggtgcgcttagatgtgtct
cgactcgttgtcgtgggaaccgggaggtcgatcagcgccatgcaccacggagcggtcctg
gagggggcgtggggctcgggggaagccactgctgatcacggtgcggatcgcacggccgtc
aatgtggccgacggtgacgccgccctggcactactgcgcgccgagctgcgacccggggat
gtggtcttggtcaaggcctcgaacgcggccgggctgggtgcggtggccgatgcattggtc
gcagacgacacatgcgggagtgtgcgcccatga
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