Methylophaga thalassica: VSX76_05325
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Entry
VSX76_05325 CDS
T09743
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mtha
Methylophaga thalassica
Pathway
mtha00300
Lysine biosynthesis
mtha00550
Peptidoglycan biosynthesis
mtha01100
Metabolic pathways
mtha01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mtha00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
VSX76_05325 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
VSX76_05325 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
VSX76_05325 (murF)
Enzymes [BR:
mtha01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
VSX76_05325 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
WVI86033
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Position
1:731464..732816
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AA seq
450 aa
AA seq
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MGLQLPLKQIAEIIAADMPVVDATVTGAVIDSRKVTPGDLFIAFKGEHVDGHEYVAKARE
NGAVAALVSEYQDDELPQIKVDDVRVAFGQIARAWLAECKAKVVAITGSNGKTSLKEMVK
AILSEVGTVSATQGNLNNDLGVPLTVCRIDKNDDYAVIEMGTNHPGEIAYLMSIVSPDVS
VINNIASAHLEGLGSEEGIAKEKGSIYQGLKQNGVAIVNADMPYDTIWQPLIADRKTIRF
ALQNNADIHAEYIQPEPASSHFLVHIDGVNHHMTLPLPGLHNVSNALAAIAVSVALDIPV
DAMVRGLNKIQAVPHRLQMRKGLSDSRLIDDTYNANPGSYLRALETLAGFQEPRWLVLGD
FGELGEEADAIHQTMGLQAKSAGVTTLFTVGEKSQLAAAAFGDNAIHFEDVQTLQQLLQN
TLTADVTCLIKGSRFMQLDKLADALVAEAQ
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atgggtctgcaactgccacttaaacagattgctgaaattatcgcagctgatatgccggtc
gttgatgctaccgttactggtgcggtgattgattctcgcaaggtaacgccgggtgatttg
tttattgcctttaaaggtgaacatgttgatggtcacgaatatgttgctaaagccagagaa
aacggtgctgtcgcggcattagtcagtgaatatcaggatgatgaattaccacagattaag
gtcgatgatgtccgcgtcgcatttgggcagatcgcccgggcctggttagctgagtgcaaa
gcaaaagtggttgctatcacaggcagtaatggcaaaaccagtttgaaagaaatggttaaa
gctatcttgtcagaagtgggcactgtatcggcaactcagggtaatttgaataatgatctg
ggtgtaccgttaaccgtttgtcgaatcgacaaaaatgatgattatgctgtgatcgagatg
ggcaccaatcatcctggtgaaattgcttatctgatgagcatcgtgtcacctgacgtgtca
gttatcaataatattgcttcagctcatcttgaaggattgggtagtgaagaaggtattgcc
aaagaaaaaggcagtatctatcagggcttgaagcaaaacggtgtagctatagtgaatgcg
gatatgccttatgacacaatctggcagcctttaattgctgatagaaaaactattcggttt
gctttgcaaaataatgctgatattcatgctgaatatattcagccagaacccgcatctagt
catttcctggtgcatatcgacggtgtaaaccatcacatgactttacctctgccgggattg
cataacgtcagcaatgcattggcagctatcgctgtgagcgttgcccttgatattccggtt
gatgccatggtgcgtggattgaacaaaatacaagcagtgccccatcgactacaaatgcgt
aaaggcctgtcagacagccgtttaattgatgatacctacaatgctaatcccggctcatat
cttcgggccttagaaaccttagctggatttcaagaaccgcgttggctggtactcggtgat
tttggtgagttgggtgaagaggctgatgccatccatcaaaccatgggattacaagcgaaa
tctgctggtgtgacgacattatttacggtcggagaaaaaagccaacttgcggcagccgcg
tttggtgataacgctattcattttgaggatgtacaaacattgcaacagcttttgcaaaac
acactaactgcagatgtgacttgtttaattaaaggatcacgctttatgcaactcgacaaa
ctggccgatgcgctggtagcggaggcacagtaa
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