Methylophaga thalassica: VSX76_11255
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Entry
VSX76_11255 CDS
T09743
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
mtha
Methylophaga thalassica
Pathway
mtha00230
Purine metabolism
mtha01100
Metabolic pathways
mtha01110
Biosynthesis of secondary metabolites
Module
mtha_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mtha00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
VSX76_11255 (purL)
Enzymes [BR:
mtha01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
VSX76_11255 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
DUF2577
Motif
Other DBs
NCBI-ProteinID:
WVI84353
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Position
1:complement(1986471..1990355)
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AA seq
1294 aa
AA seq
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MLQLIGRPAFSAFRLEKLLNSIQAEVPVVTAVRTEFRYFIEIDDECILPSAEHQILETLL
EAEARESEAKDNESFFLVTPRPGTISPWSSKATDITINSGVKNVERVERGVAFFVESSET
LSQHQKNRVASFLHDRMIETVFESVDETDRLFMHGESRSLVSVDILNGGREALALANQQM
GLALAEDEIDYLFENFTLLDRNPNDIELMMFAQANSEHCRHKIFRADWIIDGETQPHTLF
NMIRNTHDLHPEGVVKAYSDNSSVIEGPRSHRFQVDMATGHYHYEGEVQHILMKVETHNH
PTAISPFPGASTGAGGEIRDEGATGRGSKPKAGLTGFSVSNLEIPGFEQPWETPYGKPAR
MASAREIMIDGPLGGAAFNNEFGRPNLCGYFRTYEVQVPTDNGFEVRGYHKPIMVAGGMG
SIRPQHVEKGIMDPSVQLIVLGGPAMLIGLGGSAASSVNSGASDEGLDFASVQRGNPEME
RRCQEVIDRCVALGEQNPIIAIHDVGAGGLSNAFPELVDDSGRGGRFELRVIPNDEPSMS
PMEIWCNESQERYVLGVHPDRIDEFKAICERERCPWAVVGETTEEEHLLLGDADNETSPI
DMPLSLLLGKPPKMLREVKHVKQSYPELDLDGVSARDALERVLKLPTVASKNFLITIGDR
SVTGLVARDQMVGPWQVPVADCAVTLADHHDVLGEAMSMGERAPIALINAAASGRIAVGE
AITNIAAAKIDKLGDIKLSANWMAACGHPGEDALLYDTVKAIGMELCPELGIAIPVGKDS
LSMKTVWDEKGETKAVTSPLSLIISAFAPVTDASLTSTPQLRTDLGETDLIYIDLGQNKN
RLGGSALAQVFSQVGTTAPDIDDAVHLKNFFNAIQRLKNEALLLAYHDRGDGGLAVTLAE
MAFAGHCGLDIHLNGLGDALSVLFNEELGAVIQVPHADLNHVMNILKDYNLTSMSFAIGK
VTEQQQIRIHVEKELVIDESRVTLQRFWAETSYQMQALRDNPDCAKQEFDALLDENDPGL
FAKPSFNPAENIASSLIVSGHRPKVAILREQGVNGQVEMAASFDHAGFNAIDVHMSDVLE
GRIELTDFVGLVACGGFSYGDVLGAGRGWASTILHNDRARQQFTDFFHRPDTFALGVCNG
CQMLSQLKELIPGSDHWPRFSRNTSEQFEARFSLVEIVESPSVLLKGMAGSVMPIAVAHG
EGRVDYSETGSEQQAIVAMRYVDHYGQATESYPMNPNGSVGGVTALTTDDGRVTIMMPHP
ERVTRTVQHSWHPDDWGKDGPWARLFQNARCWVN
NT seq
3885 nt
NT seq
+upstream
nt +downstream
nt
atgctgcaattgattggccgcccggctttttctgctttccgtctggagaaattactaaac
agcattcaggctgaagtgcctgttgtcacggctgttagaactgagtttcgttattttatt
gaaatagatgatgaatgtattttgccttcggcggagcatcagattcttgaaacactgctt
gaagcagaagcgcgcgaaagcgaagcaaaagacaatgaaagctttttcctggtgacacca
agacccggcactatttctccctggtcaagcaaagccaccgatatcaccattaacagtggt
gtgaaaaatgttgaacgtgttgagcggggcgttgctttttttgttgaatcctctgaaaca
ctcagtcaacaccagaaaaatcgcgttgctagcttcttacacgaccgtatgatcgaaacg
gtatttgaaagcgtggatgaaaccgatcgtttatttatgcatggcgagtcacggtcatta
gtcagtgtcgatattctaaacggtggtcgcgaggcattagcactggctaatcagcaaatg
ggcctggctttagccgaagacgaaattgattatctttttgaaaatttcaccttattagac
cgtaatcccaacgatattgaattaatgatgtttgctcaggcgaactcagagcattgtcgt
cataaaattttccgtgctgactggatcattgatggcgagacacagcctcataccttattc
aatatgatccgcaacacccatgaccttcatcctgaaggggttgtgaaagcctacagtgac
aactcatctgtaattgaaggcccaagaagtcaccgttttcaggtcgatatggcgactggc
cattatcattatgaaggtgaagttcagcacatcctgatgaaagtggaaacgcataaccat
cctacggccatctctccgttccctggtgcatccactggtgcaggtggtgagattcgtgac
gaaggtgcaacaggacggggttcaaaaccgaaagcaggcttaaccgggttttctgtttcc
aatctggaaattcctggctttgaacaaccctgggaaacaccttacggtaaaccggctcgt
atggcctctgcccgtgaaatcatgattgatggtcctttgggcggggccgcatttaataat
gaatttggtcgccccaatctgtgcggttacttccgtacttatgaagtgcaggtgccgacg
gataatggttttgaagtacgtgggtaccataaaccgattatggttgccggtggcatgggt
tctatccgtccacagcatgttgaaaaaggcattatggatccaagcgtacaattaattgta
ctgggtggtccagccatgttaatcggactgggcggtagtgcggcttcatccgtcaattct
ggtgccagtgatgaagggctggactttgcttctgtacagcgtggcaatcctgaaatggaa
cgtcgttgtcaggaagtcattgaccgctgtgttgcgctgggtgagcaaaacccgatcatt
gcgattcacgatgtcggtgcaggtggtctgtccaacgctttccctgaactcgtcgatgac
agtggtcgtggtggccgttttgaactgcgtgttatcccaaatgatgaacccagtatgtca
ccgatggaaatctggtgtaatgaatctcaggagcgttatgtgcttggcgttcaccctgat
cgtattgatgaattcaaagcgatctgtgagcgtgaacgttgcccgtgggccgtggtaggt
gaaacgacagaagaagaacatttattactcggtgatgctgataatgaaacatcaccgatt
gatatgccgttatcacttttattgggtaaaccacccaaaatgctgcgtgaagtgaagcat
gttaaacaaagctatcctgagcttgatcttgacggtgtatctgcccgtgacgcattggag
cgtgtacttaaactacctactgtagccagcaaaaacttcttgattaccattggtgacaga
agtgtgactggtctggttgcacgtgaccagatggtcggcccgtggcaagtccctgtcgct
gattgcgctgtgacattggctgatcatcacgatgtgttaggtgaagccatgtcgatgggc
gagcgcgcgccaattgctctgattaatgcggctgcatctggtcggatcgcggtaggtgaa
gcgattaccaatattgcagcggcaaaaattgataaattaggcgacattaaactgtctgct
aactggatggccgcttgtggtcaccccggtgaagatgctctgctgtatgacacagttaaa
gcgattgggatggaattgtgccctgagttaggtattgcgattccggttggcaaagattca
ttgtcaatgaaaacggtatgggatgaaaaaggtgaaaccaaagcggtaacatcaccttta
tctttgattatcagtgcctttgcacctgttactgatgcaagtctaaccagcacaccacaa
ttgcgaacagatctaggtgaaacagatcttatttatatcgatttgggacaaaataaaaac
cgtttaggtggttctgcacttgctcaggtattcagtcaggtcggcactacagcgcctgat
attgatgatgcggtacatttgaaaaacttctttaatgccattcaacgcctgaagaatgaa
gcgttgttattggcgtaccacgatagaggggacggcggtcttgctgtcacgcttgctgaa
atggcgtttgctggtcactgtggtctggacattcatctcaatggtttaggagatgcgctg
tcagtcttgttcaatgaagaattaggtgcggtgattcaagtgcctcatgctgatttgaac
cacgtaatgaatattcttaaagattacaatttgacctcaatgtcatttgctatcggtaaa
gtgacagaacaacagcagattcgtattcatgttgaaaaagaactggtgattgatgaatca
cgtgtgacattgcagcgcttctgggctgaaaccagctatcaaatgcaggcattacgtgat
aacccagactgtgctaaacaagagtttgatgctttattggatgagaatgatccgggctta
tttgccaagccatcatttaacccagctgaaaatatcgccagttcacttatcgttagtgga
catcgtccaaaagtcgccattctgcgtgagcagggggttaatggtcaggtagaaatggct
gcctcatttgatcatgctggttttaatgcgattgatgtacatatgagcgatgttctggaa
ggacgcattgaactgacggactttgttggtttagtggcctgtggtggtttctcttatggt
gacgtgcttggtgctggtcgtggttgggcaagtactattttgcataacgatcgtgcacgt
caacagttcacagatttcttccatcgtcctgatacctttgcactgggtgtatgtaatggc
tgtcagatgttatcgcagttaaaagagctgattccgggtagtgatcactggcctcgcttc
tcacgcaacacatctgaacagtttgaagcacgcttttctctggtagaaattgttgagtcg
ccttctgtactgctgaaaggtatggcgggttcagtcatgccaatcgccgttgctcatggt
gaaggccgtgtggattacagtgagacaggttcagaacagcaggcaatcgtcgccatgcgt
tatgtcgatcattatggtcaggcaacagaaagttatccaatgaatccgaatggttcggtc
ggtggtgtgactgctctgacaacagatgatggtcgagtaacgattatgatgcctcatcct
gagcgcgtcacccgtacagttcagcactcctggcatccagatgactggggtaaggatggt
ccatgggcaagactgttccagaatgccagatgttgggttaactaa
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