KEGG   Macaca thibetana thibetana (Pere David's macaque): 126929358
Entry
126929358         CDS       T08579                                 
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
mthb  Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb01522  Endocrine resistance
mthb04015  Rap1 signaling pathway
mthb04020  Calcium signaling pathway
mthb04024  cAMP signaling pathway
mthb04072  Phospholipase D signaling pathway
mthb04081  Hormone signaling
mthb04082  Neuroactive ligand signaling
mthb04261  Adrenergic signaling in cardiomyocytes
mthb04270  Vascular smooth muscle contraction
mthb04540  Gap junction
mthb04611  Platelet activation
mthb04713  Circadian entrainment
mthb04714  Thermogenesis
mthb04724  Glutamatergic synapse
mthb04726  Serotonergic synapse
mthb04728  Dopaminergic synapse
mthb04730  Long-term depression
mthb04750  Inflammatory mediator regulation of TRP channels
mthb04911  Insulin secretion
mthb04912  GnRH signaling pathway
mthb04913  Ovarian steroidogenesis
mthb04915  Estrogen signaling pathway
mthb04916  Melanogenesis
mthb04918  Thyroid hormone synthesis
mthb04921  Oxytocin signaling pathway
mthb04922  Glucagon signaling pathway
mthb04923  Regulation of lipolysis in adipocytes
mthb04924  Renin secretion
mthb04925  Aldosterone synthesis and secretion
mthb04926  Relaxin signaling pathway
mthb04927  Cortisol synthesis and secretion
mthb04928  Parathyroid hormone synthesis, secretion and action
mthb04934  Cushing syndrome
mthb04935  Growth hormone synthesis, secretion and action
mthb04961  Endocrine and other factor-regulated calcium reabsorption
mthb04962  Vasopressin-regulated water reabsorption
mthb04970  Salivary secretion
mthb04971  Gastric acid secretion
mthb04972  Pancreatic secretion
mthb04976  Bile secretion
mthb05012  Parkinson disease
mthb05030  Cocaine addiction
mthb05031  Amphetamine addiction
mthb05032  Morphine addiction
mthb05034  Alcoholism
mthb05142  Chagas disease
mthb05146  Amoebiasis
mthb05163  Human cytomegalovirus infection
mthb05165  Human papillomavirus infection
mthb05200  Pathways in cancer
mthb05207  Chemical carcinogenesis - receptor activation
mthb05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mthb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    126929358
   04020 Calcium signaling pathway
    126929358
   04072 Phospholipase D signaling pathway
    126929358
   04024 cAMP signaling pathway
    126929358
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    126929358
   04081 Hormone signaling
    126929358
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    126929358
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    126929358
  09152 Endocrine system
   04911 Insulin secretion
    126929358
   04922 Glucagon signaling pathway
    126929358
   04923 Regulation of lipolysis in adipocytes
    126929358
   04912 GnRH signaling pathway
    126929358
   04913 Ovarian steroidogenesis
    126929358
   04915 Estrogen signaling pathway
    126929358
   04921 Oxytocin signaling pathway
    126929358
   04926 Relaxin signaling pathway
    126929358
   04935 Growth hormone synthesis, secretion and action
    126929358
   04918 Thyroid hormone synthesis
    126929358
   04928 Parathyroid hormone synthesis, secretion and action
    126929358
   04916 Melanogenesis
    126929358
   04924 Renin secretion
    126929358
   04925 Aldosterone synthesis and secretion
    126929358
   04927 Cortisol synthesis and secretion
    126929358
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    126929358
   04270 Vascular smooth muscle contraction
    126929358
  09154 Digestive system
   04970 Salivary secretion
    126929358
   04971 Gastric acid secretion
    126929358
   04972 Pancreatic secretion
    126929358
   04976 Bile secretion
    126929358
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    126929358
   04961 Endocrine and other factor-regulated calcium reabsorption
    126929358
  09156 Nervous system
   04724 Glutamatergic synapse
    126929358
   04728 Dopaminergic synapse
    126929358
   04726 Serotonergic synapse
    126929358
   04730 Long-term depression
    126929358
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    126929358
  09159 Environmental adaptation
   04713 Circadian entrainment
    126929358
   04714 Thermogenesis
    126929358
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    126929358
   05207 Chemical carcinogenesis - receptor activation
    126929358
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    126929358
   05165 Human papillomavirus infection
    126929358
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    126929358
   05142 Chagas disease
    126929358
  09164 Neurodegenerative disease
   05012 Parkinson disease
    126929358
  09165 Substance dependence
   05030 Cocaine addiction
    126929358
   05031 Amphetamine addiction
    126929358
   05032 Morphine addiction
    126929358
   05034 Alcoholism
    126929358
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    126929358
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    126929358
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    126929358
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mthb04147]
    126929358
   04031 GTP-binding proteins [BR:mthb04031]
    126929358
Exosome [BR:mthb04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   126929358
  Exosomal proteins of other body fluids (saliva and urine)
   126929358
  Exosomal proteins of colorectal cancer cells
   126929358
  Exosomal proteins of bladder cancer cells
   126929358
GTP-binding proteins [BR:mthb04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    126929358
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA GTP_EFTU
Other DBs
NCBI-GeneID: 126929358
NCBI-ProteinID: XP_050601525
LinkDB
Position
10:complement(40998601..41365237)
AA seq 1058 aa
MGVRNCLDGNNMSGQRDIPPEIGEQPDQPSLEAPGAAAPGAGPSPAEEMETEPPHNEPIP
IKNESEACGPPEVSRPNFQVLNPAFREAGAHGSYSPPPEEAMPFEVEQPSLGSFWPTLEQ
PGSPSGAHAGLEAFGPAFMEPGAFSGARPGLGGYSPPPEEAMPFEFDQPAKTGCSQPLLQ
VPDLAPGGPGAAGVPGAPPEEPQALRPPKTGSRGGYSPPPEETMPFELDGEGSGDDSPPP
GLSRVIAQVDRGGQFAAVAASSAVRLTPAANAPPLWVPGAIGSPSREAVRPPPNFTGSGP
PMEISGPPLEIGSAPAGVDDAPVNMDSPPIALDGPPIEVSGAPDKRERAERPPVEEEAAE
MEGSTAADAAEGGKVPSPGYGSPAAGAASTDTATGAARAAPADPDSGAAPEDPDSGAAPA
ASADLDSGAAPDAPADPDSGAAPDAPADPDSGAAPDAPADPDSGAAPDAPAVPDAGAAPD
APADPDAGAAPEVPAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQAARAASAAPAS
GARRKLHHLRPPSPEIQAADPPTPRPARASAWRGKSERSCGRRGYYDEGAASSDDDSSGD
ESDDGTFGCIRWFQHRRNRRRRKPQRNLLRNFLMQAFGGCFGRSESPQPKASHSSKVKKV
PLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTI
VKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPP
VELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQ
YFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQ
CFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDL
LAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGR
HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
NT seq 3177 nt   +upstreamnt  +downstreamnt
atgggcgtgcgcaactgcctcgacggcaataatatgtcaggacaacgcgatatcccccct
gaaatcggggaacagcccgatcaaccatctttggaggccccaggggcagctgcccccggt
gctgggcctagcccagccgaagagatggagaccgaaccgcctcacaacgagcccatcccc
atcaagaatgagagcgaggcctgtggacccccagaggtctccaggcccaactttcaggtc
ctcaacccggcattcagggaagctggagcccatggaagctacagcccacctcctgaggaa
gcaatgcccttcgaggtcgaacagcccagcttgggaagcttctggcctacactggagcag
cctggatcccccagtggggcccatgcaggccttgaggccttcggcccagcattcatggaa
cctggagccttcagtggtgccagaccaggcctgggaggatacagccctccaccagaagaa
gctatgccctttgagtttgaccagcctgccaagacaggctgcagtcaacctctcttacag
gtcccagaccttgctccaggaggcccaggtgctgcaggggtccccggagctcctcccgag
gagccccaagccctcaggcctccaaagactggctccagaggaggctacagccctccccct
gaggagactatgccatttgagcttgatggagaaggatctggggacgacagcccacccccg
gggctttcccgagttatcgcacaagttgaccgcggtggccagttcgcggcagtcgcggcc
tcgagtgcggtccgcctcactcccgccgcgaacgcgcctcccctctgggtcccaggcgcc
atcggcagcccatcccgagaggctgtcagacctcctcctaacttcacgggcagcggcccc
ccgatggagatctccggacccccgctcgagattggcagcgcccccgctggggtcgacgac
gctcccgtcaacatggacagccccccaatcgcgcttgacggcccgcccatcgaggtctcc
ggagccccagataagagagagcgagcagagagacccccagttgaggaggaagcagcagag
atggaaggaagcacagccgctgatgccgcggagggaggaaaagtcccctctccggggtac
ggatcccctgccgccggggcagcttcaacggataccgccaccggggcagcccgtgcagcc
ccagcggatcccgactccggggcagccccagaagatcccgactccggggcagcccctgcc
gcctcggccgatctcgactccggggcggcccctgacgccccagccgatcccgactccggg
gcggcccctgacgccccggccgatcccgactctggggcggcccctgacgccccggccgat
cccgactccggggcggcccctgacgccccagcggttccagatgccggggcagcccctgac
gccccagccgatccagatgccggggcagcccctgaggttcccgcggcccctgcggctgct
gagacccgggcagcccatgtcgccccagctgcgcctgacgccggggctcccactgcccca
gccgcttctgccacccgggcagcccaagccgcccgggcggcctcggcagcccctgcctcc
ggggccagacgcaagctccatcaccttagaccccccagccccgagatccaggctgccgat
ccgcctactccgcggcctgctcgcgcgtctgcctggcggggcaagtccgagcgcagctgc
ggccgccgcgggtactacgatgaaggggcggccagcagcgacgatgactccagcggagac
gagtccgacgatgggaccttcggatgcatccgctggtttcagcatcggcgaaatcgccgc
cgccgaaagccccagcgcaacttactccgcaacttcctcatgcaagccttcgggggctgc
ttcggtcgatctgagagtccccagcccaaagcctcgcactcctccaaggtcaagaaggta
cccctggcggagaagcgcagacagatgcgcaaagaagccctggagaagcgggcccagaag
cgcgcagagaagaaacgcagcaagctcatcgacaaacaactccaggacgaaaagatgggc
tacatgtgtacgcaccgcctgctgcttctaggtgctggagaatctggtaaaagcaccatt
gtgaagcagatgaggatcctgcatgttaatgggtttaatggagagggcggcgaagaggac
ccgcaggctgcaaggagcaacagcgatggtgagaaggcaaccaaagtgcaggacatcaaa
aacaacctgaaagaggcaatcgaaaccattgtggccgccatgagcaacctggtgcccccc
gtggagctggccaaccccgagaaccagttcagagtggactacattctgagtgtgatgaac
gtgcctgactttgacttccctcccgaattctacgagcatgccaaggctctgtgggaggac
gaaggagtacgtgcctgctatgaacgctccaatgagtaccagctgattgactgtgcccag
tacttcctggacaagatcgatgtgatcaagcaggctgactatgtgccgagcgaccaggac
ctgcttcgctgccgcgtcctgacttctggaatcttcgagaccaagttccaggtggacaaa
gtcaacttccacatgtttgacgtgggtggccagcgcgatgaacgccgcaagtggatccag
tgcttcaacgatgtgactgccatcatcttcgtggtggccagcagcagctacaacatggtc
atccgggaggacaaccagaccaaccgcctgcaggaggctctgaacctcttcaagagcatc
tggaacaacagatggctgcgcaccatctctgtgattctgttcctcaacaagcaagatctg
ctcgctgagaaagtccttgctgggaaatcgaagattgaggactactttccagaatttgct
cgctacactactcctgaggatgctactcccgagcccggagaggacccacgcgtgacccgg
gccaagtacttcattcgagatgagtttctgaggatcagcactgccagtggagatgggcgt
cactactgctaccctcacttcacctgcgctgtggacactgagaacatccgccgtgtgttc
aacgactgccgtgacatcattcagcgcatgcaccttcgtcagtacgagctgctctaa

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