Macaca thibetana thibetana (Pere David's macaque): 126932091
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Entry
126932091 CDS
T08579
Name
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
KO
K13298
dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:
3.1.4.17
3.1.4.35
]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb00230
Purine metabolism
mthb01100
Metabolic pathways
mthb04934
Cushing syndrome
mthb05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
126932091
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
126932091
09167 Endocrine and metabolic disease
04934 Cushing syndrome
126932091
Enzymes [BR:
mthb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
126932091
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
126932091
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Gene cluster
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Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD-CE
HD
Motif
Other DBs
NCBI-GeneID:
126932091
NCBI-ProteinID:
XP_050606567
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Position
12:64826380..65293787
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AA seq
933 aa
AA seq
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MAASRLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSQGQGALGPRPSLAGTSS
LAHSTCKGGSSIGGGIGPNGSAHSQPLPGGGDCGGVPLSPSWASGSRGDGNLQRRASQKE
LRKSFARSKAIHVNRTYDEQATSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVERAAAGKKSLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELLSPKCSADAENSFKESMEKSSYSDWLINNSIAELVA
STGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAINDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSG
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGEYDWNIKNHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVAA
NRSKWEELHQKRLLASTASSSPASVMVATEDRN
NT seq
2802 nt
NT seq
+upstream
nt +downstream
nt
atggcagcctcccgcctggactttggggaggtggaaactttcctggacaggcacccagag
ttgtttgaagattacttgatgcggaaggggaagcaggagatggttgaaaagtggctgcag
aggcatagtcagggtcagggggctttaggtccaaggccctctttggctggtaccagcagc
ttggctcacagcacctgcaaaggtggcagcagcattggtggtggcattggaccaaatggc
tctgcccatagccagcctcttcccggtggcggggactgtggtggggttcccttgagtccc
agctgggccagtggcagcaggggcgatgggaacctgcagcggagagcttctcagaaagag
ctaaggaagagttttgcccgctccaaggccatccacgtgaacaggacttacgatgaacag
gcgacctcccgggctcaggaacccctgagcagtgtacgacggagggcacttctccggaag
gccagctccctgccccccaccacagcccatattctcagtgcgctgctggaatcgagagtg
aatctgcctcagtatcctcctacagccatcgactacaagtgccacctgaaaaagcataat
gagcgtcagttctttctggaattggtcaaagatatctccaatgaccttgacctcaccagc
ctgagctacaagattctcatctttgtctgccttatggtggacgctgaccgatgctctctt
ttcctggtggaaagggcagctgctggcaagaagagcttggtctccaaattctttgatgtg
catgcaggaacccctctgctgccttgcagcagcacagagaactcaaatgaggtgcaggtc
ccctggggcaaaggcatcattggctatgtcggggagcatggagaaacggtcaacattcct
gatgcctaccaggatcgacgattcaatgatgaaatcgacaagctaactggatacaagacg
aaatcattattgtgcatgcctatccgaagcagtgatggtgagattattggtgtggcccaa
gcgataaataagattcctgaaggagctccatttactgaagatgatgaaaaagttatgcag
atgtatcttccgttttgtggaattgccatatctaacgctcagctctttgctgcttcaagg
aaagaatatgaaagaagcagagctttgctagaggtggttaatgacctctttgaagaacaa
actgacctggagaaaattgtcaagaaaataatgcatcgggcccaaactctgctgaaatgt
gaacgctgttctgttttactcctagaggacatcgaatcaccagtggtgaaatttaccaaa
tcctttgaattgctgtccccgaagtgcagtgctgatgctgagaacagtttcaaagaaagc
atggagaaatcatcgtactccgactggctaataaataatagcattgctgagctggttgct
tcaacaggcctcccagtgaacatcagtgatgcctaccaggatccgcgctttgatgcagag
gcggaccagatatctggttttcacataagatctgttctctgtgtccctatttggaatagc
aaccaccaaataattggagtggctcaagtgttaaatagacttgatgggaaaccttttgat
gatgcggatcaacgactttttgaggcttttgtcatcttttgtggacttggcatcaacaac
acaattatgtatgatcaagtgaagaagtcctgggccaagcagtctgtggctcttgatgtg
ctatcatatcatgcaacatgttcaaaagctgaagttgacaagtttaaggcagccaacatc
cctctggtgtcagaacttgccatcaatgacattcattttgatgacttttctcttgatgtt
gatgccatgatcacagctgctctccggatgttcatggagctggggatggtacagaaattt
aaaattgactatgagacactgtgtaggtggcttttaacagtgaggaaaaactatcggatg
gttctgtatcacaactggagacatgccttcaacgtgtgtcagctgatgttcgcgatgtta
accactgctgggtttcaagagattctgaccgaggtggaaattttagctgtgattgtggga
tgcctgtgtcatgacctcgaccacaggggaaccaacaatgccttccaagctaagagcggt
tccgccctggcccaactctatggaacctctgctaccttggagcatcaccatttcaaccac
gccgtgatgatccttcaaagcgagggtcacaatatctttgctaacctgtcctccaaggaa
tatagtgaccttatgcagcttttgaagcagtcaatattggcaacagacctcacgctgtac
tttgagaggagaactgaattctttgaacttgtcagtaaaggagaatacgattggaacatc
aaaaaccatcgtgatgtatttcgatcaatgttaatgacagcctgtgaccttggagccgtg
accaaaccgtgggagatctcgagacaggtggcagaacttgtaaccagtgagttctttgaa
caaggagatcgggagagattagagctcaaactcactccttcggcaatttttgatcggaac
cggaaagatgaactgcctcggttgcaactggagtggattgacagcatctgcatgcctttg
tatcaggcactggtgaaggtcaatgtgaaactgaagccgatgctagattcagtagctgca
aacagaagtaagtgggaagagctgcaccaaaaacggctgctggcctcaactgcctcatcc
tcccctgccagtgttatggtagccacggaagacaggaactaa
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