Macaca thibetana thibetana (Pere David's macaque): 126932178
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Entry
126932178 CDS
T08579
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb00190
Oxidative phosphorylation
mthb01100
Metabolic pathways
mthb04714
Thermogenesis
mthb04723
Retrograde endocannabinoid signaling
mthb04932
Non-alcoholic fatty liver disease
mthb05010
Alzheimer disease
mthb05012
Parkinson disease
mthb05014
Amyotrophic lateral sclerosis
mthb05016
Huntington disease
mthb05020
Prion disease
mthb05022
Pathways of neurodegeneration - multiple diseases
mthb05208
Chemical carcinogenesis - reactive oxygen species
mthb05415
Diabetic cardiomyopathy
Module
mthb_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
126932178
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
126932178
09159 Environmental adaptation
04714 Thermogenesis
126932178
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
126932178
09164 Neurodegenerative disease
05010 Alzheimer disease
126932178
05012 Parkinson disease
126932178
05014 Amyotrophic lateral sclerosis
126932178
05016 Huntington disease
126932178
05020 Prion disease
126932178
05022 Pathways of neurodegeneration - multiple diseases
126932178
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
126932178
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
126932178
Enzymes [BR:
mthb01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
126932178
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
126932178
NCBI-ProteinID:
XP_050606779
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Position
12:36468173..36504842
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AA seq
727 aa
AA seq
DB search
MLRIPVRKALVGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMIRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDLLNR
VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYRYDHLGDSPKILQDIASGSHPFSQVLKEAKKPMVVLGSSA
LQRNDGAAILAAVSSIAQKIRMTSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTKVAVTPPGLAREDWKIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDIE
GANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttgaggatacctgtaagaaaggccttagtaggcctttctaaatctcctaaaggatgt
gttcgaacaactgccacagcagcaagcaacttgattgaagtatttgttgatggtcagtct
gtcatggtggaaccgggaacgaccgtcctccaagcttgtgagaaggttggcatgcagatc
cctcgattctgttatcatgaaaggttgtctgttgctggaaactgcaggatgtgccttgtt
gaaattgagaaagcccccaaggttgtagctgcttgtgccatgccagtaatgaagggctgg
aatatcctaacaaactcagaaaaatccaagaaagccagggaaggtgtgatggagttctta
ttagcgaatcacccactggactgtcctatttgtgaccaaggaggtgaatgtgatctgcag
gaccagtccatgatgtttggaaatgataggagccgatttttagaggggaagcgtgctgtg
gaagacaagaacattgggccattggtaaagaccatcatgacaagatgtatacagtgtact
cgctgcatcaggtttgcaagtgagattgcaggagtagatgatttgggaacaacaggcaga
ggaaatgatatgcaagttggcacatacattgaaaagatgttcatgtctgaactgtctggg
aatatcattgatatctgccctgtaggtgccctaacctctaagccctatgcctttactgcc
cggccttgggaaacaagaaagacagaatccattgatgtaatggatgcagttggaagtaat
attgtggttagcacaagaactggagaagtgatgaggattttgccacgtatgcatgaggac
atcaatgaagagtggatctctgataaaaccagatttgcctatgatgggctaaaacgtcaa
agacttaccgagccgatgatcagaaatgaaaaagggcttttaacctatacttcttgggag
gatgcactctctcgtgtagctggaatgttgcagagttttcaaggcaaagatgtggcagca
attgcaggtggcttggtggatgctgaagccctagtagctctcaaagatttacttaataga
gtggactctgacaccttatgcactgaagaggtcttccccactgcaggagctggcacagat
ttgcgttccaattatcttcttaatactacaattgctggtgtggaagaggcagatgttgta
cttctggttggtacaaatccacgttttgaggcaccactgtttaatgctagaattcgaaag
agctggctgcataatgacttaaaagtggcccttataggcagtccagtggacctcacttac
agatatgaccacctgggagactcccccaaaattcttcaagacattgcttcgggaagtcat
ccatttagccaggtcctaaaggaagctaaaaaaccaatggtggttttaggcagttctgca
ctccaaagaaatgatggagcagcaattcttgcagctgtctctagcattgcacaaaagatt
cggatgactagtggtgttactggcgattggaaagttatgaatatccttcataggattgca
agtcaagtagctgctttggaccttggctataaacctggggtggaagcaattcggaagaac
cctcccaaggtgctgtttctcctgggagcagatggaggttgtatcacacgacaggatttg
ccaaaggattgtttcattatttatcaaggacatcatggtgatgttggggctcccatagct
gatgttattctcccaggagctgcttacacagagaagtctgctacatatgtcaacactgag
ggtagagctcagcagactaaggtagcagtgacacctcctggcttggcaagagaagactgg
aaaattataagagcactctctgagattgctggaataactcttccatatgatactctggat
caagtaaggaacagattggaagaagtctctcctaatcttgttcgatatgatgatattgaa
ggggctaattacttccagcaagcaaatgagctctcaaagctagtgaaccagcagcttctt
gctgacccacttgttccacctcagctaactataaaagacttctacatgacagattcaatt
agcagagcctcacagacaatggccaaatgtgtcaaagctgtcacagagggtgcccaggca
gtagaggaaccatccatatgctga
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