KEGG   Macaca thibetana thibetana (Pere David's macaque): 126936830
Entry
126936830         CDS       T08579                                 
Name
(RefSeq) toll-like receptor 4 isoform X1
  KO
K10160  toll-like receptor 4
Organism
mthb  Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb04064  NF-kappa B signaling pathway
mthb04066  HIF-1 signaling pathway
mthb04145  Phagosome
mthb04151  PI3K-Akt signaling pathway
mthb04217  Necroptosis
mthb04613  Neutrophil extracellular trap formation
mthb04620  Toll-like receptor signaling pathway
mthb04621  NOD-like receptor signaling pathway
mthb04936  Alcoholic liver disease
mthb05132  Salmonella infection
mthb05133  Pertussis
mthb05134  Legionellosis
mthb05135  Yersinia infection
mthb05140  Leishmaniasis
mthb05142  Chagas disease
mthb05144  Malaria
mthb05145  Toxoplasmosis
mthb05146  Amoebiasis
mthb05152  Tuberculosis
mthb05161  Hepatitis B
mthb05162  Measles
mthb05164  Influenza A
mthb05170  Human immunodeficiency virus 1 infection
mthb05171  Coronavirus disease - COVID-19
mthb05205  Proteoglycans in cancer
mthb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mthb05321  Inflammatory bowel disease
mthb05323  Rheumatoid arthritis
mthb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mthb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    126936830
   04066 HIF-1 signaling pathway
    126936830
   04151 PI3K-Akt signaling pathway
    126936830
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    126936830
  09143 Cell growth and death
   04217 Necroptosis
    126936830
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    126936830
   04620 Toll-like receptor signaling pathway
    126936830
   04621 NOD-like receptor signaling pathway
    126936830
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    126936830
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    126936830
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    126936830
   05161 Hepatitis B
    126936830
   05171 Coronavirus disease - COVID-19
    126936830
   05164 Influenza A
    126936830
   05162 Measles
    126936830
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    126936830
   05135 Yersinia infection
    126936830
   05133 Pertussis
    126936830
   05134 Legionellosis
    126936830
   05152 Tuberculosis
    126936830
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    126936830
   05144 Malaria
    126936830
   05145 Toxoplasmosis
    126936830
   05140 Leishmaniasis
    126936830
   05142 Chagas disease
    126936830
  09163 Immune disease
   05323 Rheumatoid arthritis
    126936830
   05321 Inflammatory bowel disease
    126936830
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    126936830
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    126936830
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mthb04131]
    126936830
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:mthb04054]
    126936830
   04090 CD molecules [BR:mthb04090]
    126936830
   00536 Glycosaminoglycan binding proteins [BR:mthb00536]
    126936830
Membrane trafficking [BR:mthb04131]
 Endocytosis
  Phagocytosis
   Toll-like receptors
    126936830
Pattern recognition receptors [BR:mthb04054]
 Membrane-bound pattern recognition receptors
  Toll-like receptors
   126936830
CD molecules [BR:mthb04090]
 Proteins
  126936830
Glycosaminoglycan binding proteins [BR:mthb00536]
 Hyaluronan
  Cell surface receptors
   126936830
SSDB
Motif
Pfam: LRR_8 TIR LRR_4 LRR_1 LRR_14 TIR_2 LRR_9 LRR_5 LRR_6 LRR_Zer-1 LRR_EndoS ThsB_TIR LRR_R13L1-DRL21 Curto_V2
Other DBs
NCBI-GeneID: 126936830
NCBI-ProteinID: XP_050615580
LinkDB
Position
15:complement(22080694..22097032)
AA seq 826 aa
MTSALHLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNIPFSTKNLD
LSFNPLRHLGSYSFLRFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALG
AFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHL
DVSSNKIQNIYCKDLQVLHQMPLSNLSLDLSLNPINFIQPGAFKEIRLHKLTLRSNFDDL
NVMKTCIQGLAGLEVHRLVLGEFRNERNLEEFDKSSLEGLCNLTIEEFRLAYLDYYLDDI
IDLFNCLANVSSFSLVSVNIKRVEDFSYNFRWQHLELVNCKFEQFPTLELESLKRLTFTA
NKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNDVITMSSNFLG
LEQLEHLDFQHSNLKQMSQFSVFLSLRNLIYLDISHTHTRVAFNGIFDGLLSLKVLKMAG
NSFQENFLPDIFTDLKNLTFLDLSQCQLEQLSPTAFDTLNKLQVLNMSHNNFFSLDTFPY
KCLPSLQVLDYSLNHIKTSNNQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQL
LVEAERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVFSVLVVSVVAVLVYKFYFHLML
LAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA
NIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLR
QQVELYRLLSRNTYLEWEDSVLGQHIFWRRLRKALLDGRSWNPEEQ
NT seq 2481 nt   +upstreamnt  +downstreamnt
atgacgtctgccttgcacctggctgggactctgatcccagccatggccttcctctcctgc
gtgagaccagaaagctgggagccctgcgtggaggtggttcctaacattacttatcaatgc
atggagctgaatttctacaaaatccccgacaacatccccttctcaaccaagaacctggac
ctgagctttaatcccctgaggcatttaggcagctatagcttcctccgttttccagaactg
caggtgctggatttatccaggtgtgaaatccagacaattgaagatggggcatatcagagc
ctaagccacctctccaccttaatattgacaggaaaccccatccagagtttagccctggga
gccttttctggactatcaagtttacagaagctggtggctgtggagacaaatctagcatct
ctagagaacttccccattggacatctcaaaactttgaaagaacttaatgtggctcacaat
cttatccagtctttcaaattacctgagtatttttctaatctgaccaatctagagcacttg
gacgtttccagtaacaagattcaaaatatttattgcaaagacttgcaggttctacatcaa
atgcccctatccaatctctctttagacctgtccctgaaccctataaactttatccaacca
ggtgcatttaaagaaattaggcttcataagctgactttgagaagtaattttgatgattta
aatgtaatgaaaacttgtattcaaggtctggctggtttagaagtccatcgtttggttctg
ggagaatttagaaatgaaagaaacttggaagagtttgacaaatcttctctggagggattg
tgcaatttgaccattgaagaattccgattagcatacttagactactacctcgatgatatt
attgacttatttaattgtttggcaaatgtttcttcattttccctggtgagtgtgaatatt
aaaagggtagaagacttttcttataatttcagatggcaacatttagaattagttaactgt
aaatttgaacagtttcccacattggaactcgaatctctcaaaaggcttactttcactgcc
aacaaaggtgggaatgctttttcagaagttgatctaccaagccttgagtttctagatctc
agtagaaatggcttgagtttcaaaggttgctgttctcaaagtgattttgggacaaccagc
ctaaagtatttagatctgagcttcaatgatgttattaccatgagttcaaacttcttgggc
ttagaacaactagaacatctggatttccagcattccaatttgaaacagatgagtcaattt
tcagtattcctatcactcagaaacctcatttaccttgacatttctcatactcacaccaga
gttgctttcaatggcatcttcgatggcttgctcagtctcaaagtcttaaaaatggctggc
aattctttccaggaaaacttccttccagatatcttcacagatctgaaaaacttgaccttc
ctggacctctctcagtgtcaattggagcagttgtctccaacagcatttgacacactcaac
aagcttcaggtactcaatatgagccacaacaacttcttttcattggatacgtttccttat
aagtgtctgccctccctccaggttctcgattacagtctcaatcacataaagacttccaac
aaccaggaactacagcattttccaagtagtctagctttcttaaatcttactcagaatgac
tttgcttgtacttgtgaacaccagagtttcctgcagtggatcaaggaccagaggcagctc
ttggtggaagctgaacgaatggaatgtgcaacaccttcagataaacagggcatgccggtg
ctgagtttgaatattacctgtcagatgaataagaccatcattggtgtgtctgtgttcagt
gtgcttgtggtatctgttgtagcagttctggtctataagttctattttcacctgatgctt
cttgctggctgcataaagtatggtagaggtgaaaacatctatgatgcctttgttatctac
tcaagccaggatgaggactgggtaaggaatgaactagtaaagaatttagaagaaggggtg
cctccctttcagctctgccttcactacagagactttattcccggtgtggccattgctgca
aacatcatccatgaaggtttccataaaagccgaaaggtgattgttgtggtgtcccagcac
ttcatccagagccgctggtgtatctttgaatatgagattgctcagacctggcagtttctg
agcagtcgtgcaggcataatcttcattgtcctgcagaaggtggagaagaccctgctcagg
cagcaggtggagctgtaccgccttctcagcaggaacacttacctggagtgggaggacagt
gtcctggggcagcacatcttctggagacgactcagaaaagccctgttggatggcagatcg
tggaatccagaagaacagtag

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