Macaca thibetana thibetana (Pere David's macaque): 126936865
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Entry
126936865 CDS
T08579
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
126936865
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
mthb03021
]
126936865
Enzymes [BR:
mthb01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
126936865
5.6.2.5 RNA 5'-3' helicase
126936865
Transcription machinery [BR:
mthb03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
126936865
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
UvrD-helicase
AAA_22
ResIII
Helicase_RecD
AAA_16
UvrD_C_2
nSTAND3
Motif
Other DBs
NCBI-GeneID:
126936865
NCBI-ProteinID:
XP_050615612
LinkDB
All DBs
Position
15:6003762..6106370
Genome browser
AA seq
2710 aa
AA seq
DB search
MSTCCWCTPGGGSTVDFLKRYASNTPSSEFQTADEDLCYCLECVAEYHKARDELPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNDMVRRWAILTARNLGK
VDRDDYYDLQEVLICLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNASYNREIQHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVVHHLYSEVKDVLNQTDAMCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKFKAP
PCNTFVDLTSTCKTSPASYNKEESEQIGKKSRKDMHCLEASSPTFSKEPMKAQDSVLIKA
DNTIGGDNDEQNYIKDVKLEDQLSAGSCLKQSSENIFTERAEDEIKISTRKQKSVKENSS
YTPEDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT
KVQKDEICAKLSHVIKKQHRKSTLVNNTINLDENLTVSNIERFYSRKDTGVQKGGGFIHN
LSLDPSGGLDDNKNGEQKSQNNLLPEEKQLKNEELDIFYSHENSCEIQEFHVDDKDSILF
TEMANTLEKKSSSFKDLMTVPESRDEAMSNSTNVIYSNLTREQAPGISPKSDTLTDSQID
RDLHKLSLLAQASVITFPSDSPQNSSQLQRKGKEDKRCFTANQNNVGDASRGQVIIISDS
DDDDDDDERILSLEKLTKQDKRCLEKEHPEQHISTVKEEKNPVKEEKTKSLFQFEESDSQ
CFEFESASEVFSVWQDHLDNNNSVQDGEKKCLTPIANTTNGQDCTDYVSEVVKKGAEGIE
EHARPQSSRVSVEEFCEIEVKKPKRKRSEKPIPEDPVRPSSSVGNEGQSDTNKRDLIGND
FKSIDRRTTTPNSSIQRATTVSQKKSSKLCTYTEPIRKVPVSKTPKKTHSDAKKGQNRSS
NYLSCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKGPRRAFELSQRSLDYVAQLRDHGKTV
GVVDTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRQRLSDCESTDTTRAG
PHTAQNSDLLVPESDRSDYDCTGGTEVLANSNEKQLIKCMPSEPETIKAKHGSPATDGAC
PLNQCDSIVLNGTVPTSEVIVCTSEDPLRGGDSTAHHTEMATLNEGEPDSSSDIEEDNLF
LTQNDPEDMDLCSQMENDNYKFIELIHGKDTVQVEEDSVSQPQLESLSGTKCKYKDCLET
TKNQGEYCPQHSEVKAADDDVFRKPGLPPSASKPLRPTTAKIFSSKSTSRIAGLSKSLET
SSALSPSLKNKSKGIQSILKVPQPAPLVAQKPVGEMKNSSNVLHPQSPNNSNRQGCKVPF
GESKYFPSSSPVNILLSSQSVSDTFVKEVLKWKYEMFLNFDQCGPPASLCQSISRPVPVR
FHNYGDYFNVFFPLVVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEE
CELAKQLYPKENDLVFLVPERINEEKKDAERNDIQDLHEYHSGYVHKFRRTSVMRNGKAE
CYLSIQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCT
KDLLTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGL
LYCLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLG
NCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQAMHKRKEFLDYQLDELSR
QRALCRGGREIQRQELDENISKVSKERQELASKIKEVQGRPQKTQSIIILESHVICCTLS
TSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVI
SMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYIYNRN
LKTNRQTETIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKD
VSFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSGQ
GSIGFLASLQRLNVTITRAKYSLFILGHLRTLMQLLPRSFCVHVNHSPFFSPEPKYLHWA
LKENQHWNQLIQDAQKRGAIIKTCDKNYRHDAMKILKLKPVLQRSLTHPPTIAPEVSRPQ
GGLPSSKLDSGFAKTSFAASLYHTPSDSRETTLTVTSKDPERPPVHDQLRDPRLLKRMGI
EVKGGIFLWDPQPSSPQHPGATPPAGEPSFPVVHQDLGHVQQPSAVVAALSSHKPPVQGE
PPAASPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETPHTRRNSRWDKRRPEQE
DSSSKKRKLL
NT seq
8133 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtactccaggtggtggttccaccgttgacttcctaaagcgc
tatgcttccaacactccatccagtgaatttcaaacagctgacgaagatctctgctactgc
ttagagtgtgtggcagaataccacaaagcaagagatgaattgccattcttgcatgaggtt
ttatgggaattggaaaccttacgtctgataaatcactttgaaaaatccatgaaggcagaa
attggagatgatgatgagttatatatagtagacaacaatggagagatgccactgtttgac
atcactggacaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatttgcttctacatgaacgtgttaacgagttatgtgttgaagcactttgtcggatg
gaacaagccaattgctcctttcaggtgtttgacaaacatccagggatctatttgtttttg
gtccatcccaatgatatggttcggcgttgggctatcttgactgcaagaaacttggggaaa
gtggacagagatgattattatgacttacaagaagttttaatttgcctttttaaagtcatt
gagttgggacttctagagagtccagacatttatacttcttctgtcctagagaagggtaaa
ctaattcttctgccctcacacatgtatgatactaccaactacaaaagctattggttaggt
atttgcatgttgctgaccattcttgaggaacaagccatggattccctattgttgggctca
gacaaacaaaatgattttatgcaatcgatacttcacactatggagaggcaatcagatgat
gatagtgtggatcctttctggccagcattacactgttttatggtgattctggaccgcctt
ggatctaaggtctggggtcagcttattgatcctattgaggcatttcaaaccattatcaac
aatgcaagctacaatagagagatccaacatatacggaacagctctgtaaggaccaagtta
gaaccggagtcgtatttggatgatatggtgacttgcagccagatcgtatacaattataat
cctgaaaagaccaaaaaggattctggatggagaacagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagccagtgtgcttcagtcagatattggtcaagac
atgcgtgttcataacagcacatttctgtggttcatcccttttgtccagtccctcatggat
cttaaggatttgggtgtggcttacatagtagaggttgttcatcatctgtactctgaagtc
aaagatgtcctcaaccaaacagatgccatgtgtgacaaagtcactgaattttttcttcta
attttggtatcagtgattgaactgcatagaaataaaaaatgtttgcatttgctgtgggta
agttcccagcaatgggtagaagctgtcgtcaaatgtgccaagcttcctaccactgcattt
acacggagttctgagaaatcatctggaaattgctccaaaggaacagcaatgatatcatca
ctgtcgttgcattccatgccatcgaactctgtacaacttgcttgtgtgcagctgattaga
agtctccttaaagaaggttatcagcttgggcagcaatctctttgcaagcgattctgggat
aaactcaacttattccttagaggaaatttatctctaggttggcagttgactagtcaggaa
acccacgagctacaaacttgtttaaagcaaattattagaaacataaaattcaaagcacct
ccatgtaacacttttgtggatctgacttctacatgtaaaacctctcctgcatcttataat
aaagaagaaagtgaacaaatagggaagaagtctagaaaagatatgcattgtttggaagct
tccagcccaacattttctaaagaaccaatgaaagcgcaagacagtgtactgatcaaagca
gataatactataggaggtgacaatgatgagcaaaattatataaaggatgtaaaactagaa
gaccagctctcagctgggtcatgcttaaagcagagtagtgaaaacatttttactgaaaga
gctgaagatgaaattaaaataagtacaaggaagcagaagtctgtaaaggagaactcctca
tatacaccagaggattgtacttcaagaaatggtccagaaaggggatgtgacagaggaata
atagtatcaacacgtttgttgactgattctagcactgatgctttggaaaaagtgtccaca
tcaaatgaagatttctctttaaaggatgatgctcttgctaaaacctcaaaacgaaaaact
aaggtacagaaagatgaaatctgtgcaaagttatcacatgtaataaagaagcaacacagg
aagagtactttggtcaataatactatcaatttagacgaaaatttgactgtatctaacatt
gagcgtttctattcaaggaaagatacaggagttcagaaaggaggtggtttcatacacaat
ctttctttagaccctagtggtggtctggatgataataagaatggagaacaaaaatctcaa
aacaatttattgccagaagagaagcaattaaagaatgaagagttagatattttctattcc
catgaaaacagttgtgaaatacaggaatttcatgttgatgataaagattcgatcctcttt
acagaaatggccaatactttagagaagaaatcatcttcctttaaagatcttatgactgta
cctgaatcaagagatgaggcgatgagtaatagtaccaatgtgatttattctaacttgaca
agagaacaggcccctggcatcagtcctaaatctgacaccttaacggattctcagatagac
agagaccttcacaaattatctttactagctcaagccagtgttatcacgtttccatctgat
tcccctcagaactcatcccagctacaaaggaaaggaaaagaagataaaagatgtttcaca
gctaaccaaaataatgttggcgatgcctcccgtggacaggtgattattatttcagattct
gatgatgatgatgatgatgatgaaagaatcctgagtcttgagaaactcactaaacaggac
aaaagatgccttgagaaggaacatccagagcagcacatttcaacagtcaaggaggaaaag
aatccagtaaaggaagaaaagacgaagtctctttttcagtttgaggaatctgattctcag
tgttttgagtttgaaagtgcatcagaagtgttttccgtttggcaagatcatctagacaat
aataattcagttcaagatggtgagaaaaaatgtttgactcctatagccaataccacaaat
ggtcaggattgtacagattatgtatctgaagttgttaaaaaaggggcagagggtattgaa
gaacacgcaagaccacagagcagtcgtgtttctgttgaggaattttgtgaaattgaagta
aaaaagcctaagagaaaacgatctgaaaaaccaattcctgaagatcctgtgaggccttca
tcttctgtcggaaatgagggccagtctgatactaataagagagatcttattggaaatgat
tttaaaagtatagatagaaggactacaactcccaattcaagtattcagagagccactacg
gtttcacaaaagaaatcttcaaagctttgtacttatacagaacccatcaggaaagttcca
gtttctaagacccctaagaaaactcattcggatgccaaaaaaggacagaatagaagttca
aattacctcagttgtaggacaactcctgctatagtgccaccaaagaaatttcgtcagtgt
cctgaaccaacttcaacagtggagaaacttggcctgaaaaagggtcctcgtagggcattt
gagttgtcccagcgatctttggattatgtagctcagttacgtgatcatggcaaaactgtt
ggagtagttgatactcgaaaaaagactaaattaatttctcctcagaacctgtctgtcaga
aataataagaaactgctgactagtcaagaacttcagatgcaaaggcagatcagacccaaa
tcacaaaaaaatagacaaagactttctgattgtgaaagtacagatactacaagagcaggg
cctcatacagcacagaattctgacttacttgtaccagaatctgataggtcagattatgat
tgtacaggaggaactgaggtacttgccaacagtaatgaaaaacaattaataaaatgcatg
ccttctgaaccagaaaccataaaagcaaaacatgggtctccagcgactgatggtgcttgc
cctttgaaccagtgtgattctatagtgttaaatggaacagtaccaacaagtgaagtaatt
gtctgtacttcagaggaccctctgcggggaggtgattcgacagcacatcatacagagatg
gcaactttgaacgagggagagcctgactccagcagtgatatagaggaagataacttattt
ttaacacaaaatgatcctgaagatatggatttatgttcacaaatggagaatgacaattat
aaattcattgaactaattcatggaaaagatacagttcaggttgaagaagattctgtaagt
cagcctcagttggaatctttgagtggcacaaagtgtaagtacaaagattgtcttgaaacc
acaaaaaaccagggtgaatactgcccacaacactctgaagtgaaagcagcagatgacgat
gtatttcgtaaacctggtttgcctccttctgcatctaaacctttgagacctaccactgct
aagatttttagctcaaagagtacttcacgaattgctggtctttctaaatctttggaaact
tcttcagcactttcaccatctctaaaaaataagtcaaaggggatacagtcaattttgaaa
gtaccacagccagctcccctcgtagctcagaagccagtgggtgaaatgaaaaattcgagc
aatgttcttcatcctcagtctccgaataattccaacaggcaaggttgcaaagttccattt
ggtgaaagcaaatattttccatcttcctctccagtaaacattctcttgtcatcacagtct
gtctctgacaccttcgttaaagaggtcttaaaatggaaatacgaaatgtttttgaacttt
gatcagtgtgggccccctgcaagtctttgtcagtccatctcaagacctgtgcctgtcaga
tttcacaattatggagattattttaatgtttttttccctttggtggtattgaatactttt
gaaacagtggcgcaggaatggctcaactctccaaatagagagaatttctatcagttgcaa
gtacgaaaatttcctgccgattatataaaatactgggagtttgcggtttatctggaagaa
tgtgaattggctaaacagctttatccaaaggaaaacgatttggtgtttttagttcctgag
agaataaatgaagagaagaaagatgcagagagaaatgacatacaagatctccacgaatat
cattctggttatgttcataaatttcgccgcacttcagtcatgcgtaatgggaaagctgaa
tgttacctttccatccagactcaagagaattttccggccaatttaaacgaacttgtgaat
tgtattgtaatcagttctctggtaacgacacaaaggaagttgaaagccatgtctctgttg
ggtagtcggaaccaactggctagagctgttctgaatccaaaccctatggacttctgtaca
aaagatttactaactacaacatctgagagaattattgcttacttaagagatttcaatgaa
gaccaaaagaaagcaatagaaactgcatatgctatggtgaaacactcaccatcagttgcc
aaaatctgcttgattcatggaccacctggaacaggaaaatcaaaaactattgttggcctc
ctctattgtctactgacagagaaccagaggaaggggcattcagacgaaaactccaatgcc
aaaatcaaacaaaaccgtgtcctcgtgtgtgcaccttccaatgcagctgttgatgaactc
atgaaaaaaattatccttgaattcaaagaaaaatgtaaagacaagaagaatcctttagga
aactgtggagatataaatttagtacgactgggtccagaaaagtctattaataatgaggtt
ctgaagttcagtttggacagccaagtaaaccacagaatgaaaaaagatttaccttctcat
gttcaggcgatgcataaaagaaaggaatttctagattatcagttggatgagctttcccgg
cagcgagctctatgtcgaggtggacgggaaatacagaggcaagaattagatgaaaacatt
tccaaagtttctaaggaaaggcaggaacttgcttctaaaattaaagaggttcaaggacgc
ccacagaaaacacagagtatcatcatcttagagtcccatgtcatctgctgcacattgagc
acaagtggtggcttactacttgaatctgctttccgggggcaagggggtgtccccttcagc
tgtgtcattgttgatgaggctggacagtcttgtgaaattgagactcttaccccactcatc
catcgctgcaataagctcatcctagtaggagatcccaagcagctccctcccacagtcatc
tctatgaaagcacaggagtatggctacgaccagtcaatgatggctcgcttctgcagactg
ctggaagagaatgtagaacacaacatgatcagcaggctgcctattctgcagctcactgtg
cagtacaggatgcatccagatatatgcctcttcccttctaattatatttacaacagaaac
ttaaaaacaaatagacagacagaaaccattcgatgttcatcagactggccatttcaacca
tatcttgtgtttgatgtcggagatggttcagaaagacgggataatgactcatacataaat
gttcaagaaataaaactggtgatggaaataattaagcttattaaagacaaaagaaaggat
gttagttttcgaaacattggcataataactcattacaaggcccagaagacgatgattcag
aaggatttggacaaagagttcgatagaaaaggaccagcagaagtagatactgtggatgcc
ttccagggtcggcagaaggattgtgttattgttacatgtgtcagagcaaatagcgggcaa
ggttcaattggattcctggcaagtttgcagagattgaatgtcaccatcacacgagccaag
tacagcctcttcatcctcggacatttgaggaccctgatgcaacttcttcctaggagcttt
tgtgtacacgtgaaccattcgccttttttcagcccagaacccaagtatctacactgggct
ctcaaggaaaaccagcattggaatcagctgattcaggatgctcagaagcgtggtgccatt
attaagacctgtgacaaaaactatagacatgatgcaatgaagattctgaaactcaagccc
gtgctacagagaagtctcactcaccctcctaccatagccccagaggtatccagaccccag
ggtggcttgcccagcagcaagctagacagtggatttgccaagacatcttttgctgcttct
ctataccacacaccctctgactccagggaaactactcttactgttacttcaaaggaccct
gaaagacctcctgttcatgaccaacttcgggacccacgactgctgaagaggatgggcatt
gaggtcaaaggaggaatattcctatgggatccacagccctcgagcccccagcatcctgga
gcaacacctcctgcaggagagccgagcttccctgtcgttcaccaggacctgggccatgta
cagcagccttctgctgtagtggctgctctgagcagccacaaacctcccgtgcagggcgaa
cctccagctgccagtcccgaggcttccacgtgtcagagcaaatgtgatgacccagaagag
gagctctgtcacaggagagaggccagggctttcagtgaaggtgagcaggagaagtgtggt
tccgagacccctcacaccaggaggaactctaggtgggacaagaggagaccggagcaggag
gacagcagttccaagaaaagaaagcttttatag
DBGET
integrated database retrieval system
