Macaca thibetana thibetana (Pere David's macaque): 126936955
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Entry
126936955 CDS
T08579
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb00790
Folate biosynthesis
mthb01100
Metabolic pathways
mthb01240
Biosynthesis of cofactors
mthb01523
Antifolate resistance
mthb04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
126936955
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
126936955
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
126936955
Enzymes [BR:
mthb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
126936955
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
126936955
NCBI-ProteinID:
XP_050616005
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Position
15:complement(10757539..10778706)
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AA seq
588 aa
AA seq
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MSRARNHLRAALFLAAASARGVTTQVAAQRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGISSLGIDHTSLLGDTVEKIA
WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPTLEALEEGGPPLALGLDGE
HQRSNAALALQLAHCWLQRQDHHGAGEVKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW
LGRTQVLRRGPLTWYLDGAHTPSSVQACVRWFRQALQGRERPSGSGPEVRVLLFNATGDR
DPAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDE
EQASPDLWSAPSPEPAGPTSLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPVFQPPT
PPKGLLTHPVAHSGASVLHEAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcggaaccacctgcgcgccgctctattcctggcagcggcgtctgcgcgc
ggcgtaacgacccaggtcgcggcgcagcggggcttgagcgcgtggccggtgccgcaggag
cccagcatggagtaccaggatgccgtgcgcatgcttaataccctgcagaccaatgccggc
tacctggagcaggtgaagcgccagcggggtgacccccagacacagctggaagccatggaa
ctgtacctggcacggagtgggctgcaggtggaggacttggaccggctgaacatcatccac
gtcactgggacgaaggggaagggctccacttgtgccttcacggaatgtatcctccgaagc
tatggcctgaaaacgggattctttagctctccccacctggtgcaggttcgggagcggatc
cgcatcaatgggcagcccatcagtcccgagctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggatggcagctgtgtctccatgcccccctacttccgcttc
ctgacactcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtggag
gtgggcattggcggggcttatgactgcaccaacatcatcaggaagcctgtggtgtgcggc
atctcttctcttggcatcgaccacaccagcctcctgggggacacggtggagaagattgca
tggcagaaagggggcatctttaagcaaggcgtccctgccttcactgtgctccaacctgaa
ggtcccctggcagtgctgagggaccgagcccagcagatctcatgtcctctctacctgtgt
ccgacgctggaggccctggaggaaggggggccgccgctggccctgggcctggacggggag
caccagcggtccaatgccgccttggccttgcaactggcccactgctggctgcagcggcag
gaccaccatggtgctggggaggtgaaagcatccaggccggggctcctgtggcagctgccc
ctggcacccgtgttccagcccacatcccacatgcggctcgggcttcggaacacggagtgg
ctggggcggacacaggtgctgcggcgcgggccccttacctggtacctggacggcgcacac
acccccagcagcgtgcaggcctgcgtgcgctggttccgccaggcgctgcagggccgagag
aggccgagcggcagtgggcccgaggttcgagtcttgctcttcaatgctaccggggaccgg
gacccggcggccttgctgaaactgctgcagccgtgccagtttgactatgccgtcttctgc
cccaacctgacagaggtgtcatccacaggcaatgcagaccaacagaacttcacggtgaca
ctggaccaggttctgctccgctgcctggaacaccagcagcactggaaccacctggacgaa
gagcaggccagcccagacctctggagcgcccccagcccagagcctgctgggcccacatcc
ctactgctggcgccccacccaccccacacctgcagcgccagctccctcgtcttcagctgt
atttcacatgccttgcaatggatcagccaaggccgagaccctgtcttccagccacccact
cccccaaagggcctcctcacccaccctgtggctcacagtggggccagcgtactccatgag
gctgctgccatccatgtgctggtcactggcagcctgcacctggtgggtggtgtcctgaag
ctgctggagcctgcactgtcccagtag
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