KEGG   Macaca thibetana thibetana (Pere David's macaque): 126938340
Entry
126938340         CDS       T08579                                 
Name
(RefSeq) protein kinase C alpha type isoform X1
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
mthb  Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb01521  EGFR tyrosine kinase inhibitor resistance
mthb04010  MAPK signaling pathway
mthb04012  ErbB signaling pathway
mthb04014  Ras signaling pathway
mthb04015  Rap1 signaling pathway
mthb04020  Calcium signaling pathway
mthb04066  HIF-1 signaling pathway
mthb04070  Phosphatidylinositol signaling system
mthb04071  Sphingolipid signaling pathway
mthb04072  Phospholipase D signaling pathway
mthb04082  Neuroactive ligand signaling
mthb04150  mTOR signaling pathway
mthb04151  PI3K-Akt signaling pathway
mthb04261  Adrenergic signaling in cardiomyocytes
mthb04270  Vascular smooth muscle contraction
mthb04310  Wnt signaling pathway
mthb04360  Axon guidance
mthb04370  VEGF signaling pathway
mthb04510  Focal adhesion
mthb04540  Gap junction
mthb04613  Neutrophil extracellular trap formation
mthb04650  Natural killer cell mediated cytotoxicity
mthb04664  Fc epsilon RI signaling pathway
mthb04666  Fc gamma R-mediated phagocytosis
mthb04670  Leukocyte transendothelial migration
mthb04713  Circadian entrainment
mthb04720  Long-term potentiation
mthb04723  Retrograde endocannabinoid signaling
mthb04724  Glutamatergic synapse
mthb04725  Cholinergic synapse
mthb04726  Serotonergic synapse
mthb04727  GABAergic synapse
mthb04728  Dopaminergic synapse
mthb04730  Long-term depression
mthb04750  Inflammatory mediator regulation of TRP channels
mthb04911  Insulin secretion
mthb04912  GnRH signaling pathway
mthb04916  Melanogenesis
mthb04918  Thyroid hormone synthesis
mthb04919  Thyroid hormone signaling pathway
mthb04921  Oxytocin signaling pathway
mthb04925  Aldosterone synthesis and secretion
mthb04926  Relaxin signaling pathway
mthb04928  Parathyroid hormone synthesis, secretion and action
mthb04929  GnRH secretion
mthb04933  AGE-RAGE signaling pathway in diabetic complications
mthb04935  Growth hormone synthesis, secretion and action
mthb04960  Aldosterone-regulated sodium reabsorption
mthb04961  Endocrine and other factor-regulated calcium reabsorption
mthb04970  Salivary secretion
mthb04971  Gastric acid secretion
mthb04972  Pancreatic secretion
mthb05017  Spinocerebellar ataxia
mthb05022  Pathways of neurodegeneration - multiple diseases
mthb05031  Amphetamine addiction
mthb05032  Morphine addiction
mthb05143  African trypanosomiasis
mthb05146  Amoebiasis
mthb05161  Hepatitis B
mthb05163  Human cytomegalovirus infection
mthb05164  Influenza A
mthb05170  Human immunodeficiency virus 1 infection
mthb05171  Coronavirus disease - COVID-19
mthb05200  Pathways in cancer
mthb05205  Proteoglycans in cancer
mthb05206  MicroRNAs in cancer
mthb05207  Chemical carcinogenesis - receptor activation
mthb05214  Glioma
mthb05223  Non-small cell lung cancer
mthb05225  Hepatocellular carcinoma
mthb05231  Choline metabolism in cancer
mthb05415  Diabetic cardiomyopathy
mthb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mthb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    126938340
   04012 ErbB signaling pathway
    126938340
   04014 Ras signaling pathway
    126938340
   04015 Rap1 signaling pathway
    126938340
   04310 Wnt signaling pathway
    126938340
   04370 VEGF signaling pathway
    126938340
   04066 HIF-1 signaling pathway
    126938340
   04020 Calcium signaling pathway
    126938340
   04070 Phosphatidylinositol signaling system
    126938340
   04072 Phospholipase D signaling pathway
    126938340
   04071 Sphingolipid signaling pathway
    126938340
   04151 PI3K-Akt signaling pathway
    126938340
   04150 mTOR signaling pathway
    126938340
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    126938340
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    126938340
   04540 Gap junction
    126938340
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    126938340
   04650 Natural killer cell mediated cytotoxicity
    126938340
   04664 Fc epsilon RI signaling pathway
    126938340
   04666 Fc gamma R-mediated phagocytosis
    126938340
   04670 Leukocyte transendothelial migration
    126938340
  09152 Endocrine system
   04911 Insulin secretion
    126938340
   04929 GnRH secretion
    126938340
   04912 GnRH signaling pathway
    126938340
   04921 Oxytocin signaling pathway
    126938340
   04926 Relaxin signaling pathway
    126938340
   04935 Growth hormone synthesis, secretion and action
    126938340
   04918 Thyroid hormone synthesis
    126938340
   04919 Thyroid hormone signaling pathway
    126938340
   04928 Parathyroid hormone synthesis, secretion and action
    126938340
   04916 Melanogenesis
    126938340
   04925 Aldosterone synthesis and secretion
    126938340
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    126938340
   04270 Vascular smooth muscle contraction
    126938340
  09154 Digestive system
   04970 Salivary secretion
    126938340
   04971 Gastric acid secretion
    126938340
   04972 Pancreatic secretion
    126938340
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    126938340
   04961 Endocrine and other factor-regulated calcium reabsorption
    126938340
  09156 Nervous system
   04724 Glutamatergic synapse
    126938340
   04727 GABAergic synapse
    126938340
   04725 Cholinergic synapse
    126938340
   04728 Dopaminergic synapse
    126938340
   04726 Serotonergic synapse
    126938340
   04720 Long-term potentiation
    126938340
   04730 Long-term depression
    126938340
   04723 Retrograde endocannabinoid signaling
    126938340
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    126938340
  09158 Development and regeneration
   04360 Axon guidance
    126938340
  09159 Environmental adaptation
   04713 Circadian entrainment
    126938340
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    126938340
   05206 MicroRNAs in cancer
    126938340
   05205 Proteoglycans in cancer
    126938340
   05207 Chemical carcinogenesis - receptor activation
    126938340
   05231 Choline metabolism in cancer
    126938340
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    126938340
   05214 Glioma
    126938340
   05223 Non-small cell lung cancer
    126938340
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    126938340
   05161 Hepatitis B
    126938340
   05171 Coronavirus disease - COVID-19
    126938340
   05164 Influenza A
    126938340
   05163 Human cytomegalovirus infection
    126938340
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    126938340
   05143 African trypanosomiasis
    126938340
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    126938340
   05022 Pathways of neurodegeneration - multiple diseases
    126938340
  09165 Substance dependence
   05031 Amphetamine addiction
    126938340
   05032 Morphine addiction
    126938340
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    126938340
   05415 Diabetic cardiomyopathy
    126938340
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    126938340
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    126938340
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mthb01001]
    126938340
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mthb04131]
    126938340
Enzymes [BR:mthb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     126938340
Protein kinases [BR:mthb01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   126938340
Membrane trafficking [BR:mthb04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    126938340
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C ABC1 C1_2
Other DBs
NCBI-GeneID: 126938340
NCBI-ProteinID: XP_050618391
LinkDB
Position
16:complement(72884620..73400909)
AA seq 688 aa
MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME
LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG
TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV
NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA
DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG
EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRI
DWEKLENREIQPPFKPKVTLCTKMHWLQWASRSSCGKGAENFDKFFTRGQPVLTPPDQLV
IANIDQSDFEGFSYVNPQFVHPILQSAV
NT seq 2067 nt   +upstreamnt  +downstreamnt
atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc
gcgcgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacagggcttccagtgccaagtttgctgttttgtggtccacaagaggtgccatgaa
tttgttactttttcttgtccgggtgcagataagggacccgacactgatgaccccaggagc
aagcacaagttcaaaatccacacttacggaagccccaccttctgcgatcactgtgggtcc
ctgctgtatggacttatccaccaagggatgaaatgtgacacctgcgatatgaacgttcac
aagcaatgcgtcatcaatgtccccagcctctgcggaatggatcacacagagaagaggggg
cggatttacctaaaggctgaggttgctgatgaaaagctccatgtcacagtacgagatgca
aaaaatctaatccctatggatccaaacgggctttcagatccttatgtgaagctgaaactt
attcctgatcccaagaatgaaagcaaacaaaaaaccaaaaccatccgctccacactaaat
ccccagtggaatgagtcctttacattcaaattgaaaccttcagacaaagaccgacgactg
tctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatgggatccctttcc
tttggggtttcggaactaatgaagatgccagccagtggatggtacaagttgcttaaccaa
gaagaaggtgagtactacaatgtacccattccagaaggggacgaagaaggaaacatggaa
ctcaggcagaaattcgagaaagccaagcttggccctgctggcaacaaagtcatcagtccc
tctgaagacaggaaacagccttccaacaacctggaccgagtgaaactcaccgacttcaat
ttcctcatggtgctggggaaggggagttttggaaaggtgatgcttgccgacaggaagggc
acagaagaactgtatgcaatcaaaatcctgaagaaggatgtggtgattcaggatgacgac
gtggagtgcaccatggtagaaaaacgagtcttggccctgcttgacaaacccccgttcttg
acgcagctgcactcctgcttccagacagtggatcggctgtacttcgtcatggaatatgtc
aacggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaagca
gtattctatgcggcagagatttccatcggattgttctttcttcataaaagaggaatcatt
tatagggatctgaagttagataacgtcatgttggattcagaaggacatatcaaaattgct
gactttgggatgtgcaaggaacatatgatggatggagtcacgaccaggaccttctgtggg
actccagattacatcgccccagagattatcgcttatcagccatatggaaaatctgtggac
tggtgggcctatggcgtcctgttgtatgaaatgcttgccgggcagcctccatttgatggt
gaagatgaagacgagctgtttcagtctatcatggagcacaacgtttcctatccaaaatcc
ttgtccaaggaggctgtttccatctgcaaaggactaatgaccaaacacccagccaagcgg
ctgggctgcgggcctgagggggagagggacgtgagagaacatgctttcttccggaggatc
gactgggaaaaactggagaacagggagatccagccaccgttcaagcccaaagtgactttg
tgtaccaaaatgcactggcttcagtgggcttccaggtcttcgtgcggcaaaggagcagaa
aactttgacaagttcttcacacgagggcagcccgtcttaacgccgcctgatcagctggtt
atcgctaacatagaccagtctgattttgaagggttctcgtatgtcaacccccagtttgtg
caccccatcttacagagtgcggtatga

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