Macaca thibetana thibetana (Pere David's macaque): 126939534
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Entry
126939534 CDS
T08579
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb04140
Autophagy - animal
mthb04141
Protein processing in endoplasmic reticulum
mthb04210
Apoptosis
mthb04932
Non-alcoholic fatty liver disease
mthb05010
Alzheimer disease
mthb05012
Parkinson disease
mthb05014
Amyotrophic lateral sclerosis
mthb05016
Huntington disease
mthb05017
Spinocerebellar ataxia
mthb05022
Pathways of neurodegeneration - multiple diseases
mthb05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
126939534
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
126939534
09143 Cell growth and death
04210 Apoptosis
126939534
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
126939534
05012 Parkinson disease
126939534
05014 Amyotrophic lateral sclerosis
126939534
05016 Huntington disease
126939534
05017 Spinocerebellar ataxia
126939534
05022 Pathways of neurodegeneration - multiple diseases
126939534
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
126939534
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
126939534
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mthb01001
]
126939534
Enzymes [BR:
mthb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
126939534
Protein kinases [BR:
mthb01001
]
Serine/threonine kinases: Other
IRE family
126939534
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
126939534
NCBI-ProteinID:
XP_050620880
LinkDB
All DBs
Position
16:75387491..75479105
Genome browser
AA seq
977 aa
AA seq
DB search
MPARRLLLLLLTLLLPGLGIFGNTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTELKFDSGLKSKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVS
RDVEEKPAHAPARPEAPVDSMLKDVATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQF
QKELEKIQLLQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPNTSPRASNHSLCSG
SSASKAGSSPSLEQDDGDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKR
ILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAH
LGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAA
GRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQ
RQANILLGACSLECLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQ
FFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDL
LRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPY
YFHRPPEPQPPVTPDAL
NT seq
2934 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggcggctgctgctgctgctgctgacgctgctgctgcccggcctcgggatt
tttggaaataccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaacgctggat
ggaagtttacatgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagat
ccagtcctgcaggtcccaacgcatgtggaagagcctgcctttctcccagatcctaacgat
ggcagcctatatacgcttggaagcaagaataatgaaggcctgacgaaacttccttttacc
atcccagaattggtgcaggcatccccgtgccgaagttcagatggaatcctctacatgggt
aaaaagcaggacatctggtatgttattgacctcctgactggggagaagcagcagaccttg
tcatcagcctttgcagatagtctctgcccatcaacctctcttctgtatcttgggcgaaca
gaatacaccatcaccatgtacgacaccaaaacgcgagagctccggtggaatgccacctac
tttgactacgcagcctcgctgcctgaggacgacatggactacaagatgtcccactttgtg
tccaatggtgatgggctggtggtgaccgtggacagtgaatcgggggatgtcctgtggatc
caaaactacgcctcccctgtggtggccttttatgtctggcagcgggagggtctgaggaag
gtgatgcacatcaatgtcgccgtggagaccctgcgctatctgaccttcatgtctggggag
gtggggcgcatcaccaagtggaagtacccgttccccaaggagacagaggccaagagcaag
ctgacgcccactctgtatgttgggaaatactctaccagcctctatgcctctccctcaatg
gtacacgagggagttgctgtcgtgccccgcggcagcacacttcctttgctggaagggccc
cagactgatggcgtcaccattggggacaagggggagtgtgtgatcacgcccagcacagag
ctcaagtttgactccggactcaaaagcaagaacaagctcaactacttgaggaattactgg
cttctgataggccaccatgaaaccccactgtctgcatctaccaagatgctggagagattt
cccaacaatctgcccaaacatcgggaaaatgtgattcctgctgattcagagaaaaagagc
tttgaggaagttatcaacctggttgaccagacttcagaaaacgcacctaccaccgtgtct
cgggatgtggaggagaagcccgcccatgcccccgcccggcccgaggcccccgtggactcc
atgctcaaggacgtggccaccatcatcctgagcaccttcctgctgattggctgggtggcc
ttcatcatcacctaccccctgagcatgcatcagcagcagcagctccagcaccagcagttc
cagaaggaactggagaagattcagctcctgcagcagcagcagcagctgcccttccaccca
cctggagacacggctcaggacggcgagcttctggacacatctggcccatactcagagagc
tcgggcaccagcagccccaacacgtcccccagggcctccaaccactcgctctgctccggc
agctctgcctccaaggctggcagcagcccctccctggagcaagacgacggagatgaggaa
accagcatggtgatagttgggaaaatttccttctgtcccaaggacgtcctgggccatgga
gctgagggcacaattgtgtaccggggcatgtttgacaaccgtgatgtggccgtgaagagg
atcctccccgagtgttttagcttcgcagaccgtgaggtccagctgttgcgagaatcagat
gagcacccgaacgtgatccgctacttctgcacggagaaggaccggcaattccagtacatt
gccatcgagctgtgtgcagccaccctgcaagagtatgtggagcagaaggactttgcgcat
ctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcccaccttcac
tccctcaacatcgttcacagagacctaaagccccacaacattctcatatccatgcccaat
gcacatggcaagatcaaggccatgatctctgactttggcctgtgcaagaagctggcagcg
ggcaggcacagcttcagccgccgatctggggtgcctggcacagaaggctggatcgctcca
gagatgctgagcgaagactgtaaggagaaccctacctacacggtggacatcttttctgca
ggctgcgtcttttactacgtgatctctgagggcagccacccttttggcaagtccctgcag
cggcaggccaacatcctcctgggtgcctgcagcctcgagtgcttgcacccagagaagcac
gaagacgtcattgcacgtgaattgatagagaagatgattgcgatggatcctcagaaacgc
ccctcagcgaagcacgtgctgaaacacccgttcttctggagcctagagaagcagctccag
ttcttccaggacgtgagcgacagaatagaaaaggaatccctggatggcccgattgtgaag
cagttagagagaggcgggagagccgtggtgaagatggactggcgggagaacatcaccgtc
cctctccagacagacctgcgtaaattcaggacctataaaggtggttctgtcagagatctc
ctccgagccatgagaaataagaagcaccactaccgggaactgcctgcggaggtgcgggag
acgctggggtccctccctgacgacttcgtgtgctacttcacgtctcgcttcccccacctc
ctcgcacacacctaccgggccatggagctgtgcagccacgagagactcttccagccctac
tacttccacaggcccccagagccccagcccccagtgactccagatgccctctga
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