KEGG   Macaca thibetana thibetana (Pere David's macaque): 126939572
Entry
126939572         CDS       T08579                                 
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
mthb  Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb04010  MAPK signaling pathway
mthb04012  ErbB signaling pathway
mthb04620  Toll-like receptor signaling pathway
mthb04664  Fc epsilon RI signaling pathway
mthb04668  TNF signaling pathway
mthb04912  GnRH signaling pathway
mthb04926  Relaxin signaling pathway
mthb04935  Growth hormone synthesis, secretion and action
mthb04936  Alcoholic liver disease
mthb05132  Salmonella infection
mthb05135  Yersinia infection
mthb05142  Chagas disease
mthb05161  Hepatitis B
mthb05166  Human T-cell leukemia virus 1 infection
mthb05167  Kaposi sarcoma-associated herpesvirus infection
mthb05169  Epstein-Barr virus infection
mthb05208  Chemical carcinogenesis - reactive oxygen species
mthb05417  Lipid and atherosclerosis
mthb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mthb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    126939572
   04012 ErbB signaling pathway
    126939572
   04668 TNF signaling pathway
    126939572
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    126939572
   04664 Fc epsilon RI signaling pathway
    126939572
  09152 Endocrine system
   04912 GnRH signaling pathway
    126939572
   04926 Relaxin signaling pathway
    126939572
   04935 Growth hormone synthesis, secretion and action
    126939572
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    126939572
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    126939572
   05161 Hepatitis B
    126939572
   05167 Kaposi sarcoma-associated herpesvirus infection
    126939572
   05169 Epstein-Barr virus infection
    126939572
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    126939572
   05135 Yersinia infection
    126939572
  09174 Infectious disease: parasitic
   05142 Chagas disease
    126939572
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    126939572
   05418 Fluid shear stress and atherosclerosis
    126939572
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    126939572
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mthb01001]
    126939572
Enzymes [BR:mthb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     126939572
Protein kinases [BR:mthb01001]
 Serine/threonine kinases: STE group
  STE7 family
   126939572
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 126939572
NCBI-ProteinID: XP_050620956
LinkDB
Position
16:complement(9224580..9346344)
AA seq 410 aa
MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFA
NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
KDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggctccgggggcggcagcggcagcggcacc
ccgggccccgtagggtccccggcgccgggccacccggccgtcagcagcatgcagggcttt
cagataaacttctgtgaaaaggcacaaagtaaacgcaaagcactgaagttgaattttgca
aatccacctttcaaatctacagcaaggtttactctgaatcccaatcctacaggagttcaa
aacccacacatagagagactgagaacacacagcattgagtcatcaggaaaactgaagatc
tcccctgaacaacactgggatttcactgcagaggacttgaaagaccttggagaaattgga
cgaggagcttatggttctgtcaacaaaatggtccacaaaccaagtgggcaaataatggca
gttaaaagaattcggtcaacagtggatgaaaaagaacaaaaacaacttcttatggatttg
gatgtagtaatgcggagtagtgattgcccatacatcgttcagttttatggtgcactcttc
agagagggtgactgttggatctgtatggaactcatgtctacctcgtttgataagttttac
aaatatgtatatagtgtattagatgatgttattccagaagaaattttaggcaaaatcact
ttagcaactgtgaaagcactaaaccacttaaaagaaaacttgaaaattattcacagagat
atcaaaccttccaatattcttctggacagaagtggaaatattaaactctgtgacttcggc
atcagtggacagcttgtggactctattgccaagacaagagatgctggctgtaggccatac
atggcacctgaaagaatagacccaagcgcatcacgacaaggatatgatgtccgctctgat
gtctggagtttggggatcacattgtatgagttggccacaggccgatttccttatccaaag
tggaatagtgtatttgatcaactaacacaagtcgtgaaaggagatcctccgcagctgagt
aattctgaggaaagggaattctccccaagtttcatcaactttgtcaacttgtgccttacg
aaggatgaatccaaaaggccaaagtataaagagcttctgaaacatccctttattttgatg
tatgaagaacgtgccgttgaggtcgcatgctatgtttgtaaaatcctggatcaaatgcca
gctactcccagctctcccatgtatgtcgattga

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