Macaca thibetana thibetana (Pere David's macaque): 126941766
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Entry
126941766 CDS
T08579
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb00280
Valine, leucine and isoleucine degradation
mthb00640
Propanoate metabolism
mthb00785
Lipoic acid metabolism
mthb01100
Metabolic pathways
mthb01210
2-Oxocarboxylic acid metabolism
Module
mthb_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
126941766
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
126941766
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
126941766
Enzymes [BR:
mthb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
126941766
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
126941766
NCBI-ProteinID:
XP_050624430
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Position
19:45578070..46025032
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AA seq
445 aa
AA seq
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MAVAIAAARVWRPNRGLSQAALLLLWRPGARGLARSHPHRQQQQFSSLDDKPQFPGASAE
FIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILY
ESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYG
NISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGA
ASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDG
NDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHP
ISRLRHYLLSQGWWDEEQEKAWRKQSRKKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQL
RKQQESLARHLQTYGEHYPLEHFDK
NT seq
1338 nt
NT seq
+upstream
nt +downstream
nt
atggcggtagcgatcgctgcagcgagggtctggcggccaaaccgaggcctgagccaggct
gccctcttgctgctgtggcggcctggggctcggggactggctagatctcacccgcacagg
cagcagcagcagttctcatctctggatgacaagccccagttcccaggggcctcggctgag
tttatagacaagttggaattcatccagcccaatgttatctctggaatccccatctaccgt
gtcatggaccggcaaggccagatcatcaaccccagcgaggacccccacctgccaaaggag
aaggtgctgaagctctacaagagcatgacactgcttaacaccatggaccgcatcctctat
gagtctcagcggcagggccggatctccttctacatgaccaactatggcgaggagggcacg
cacgtggggagtgccgccgccctggacaacacagacctggtgtttggccagtaccgggag
gcaggtgtgctgatgtatcgcgactaccccctggaactattcatggcccagtgctatggc
aacatcagtgacttgggcaaggggcgccagatgcctgtccactacggctgcaaggaacgc
cacttcgtcactatctcctctccactggccacacagatccctcaggcggtgggggcagcc
tacgcagccaagcgggccaatgccaacagggtcgtcatctgttacttcggtgagggggcg
gccagcgagggggatgcccacgccggcttcaacttcgcggccacacttgagtgccccatc
atcttcttctgccggaacaatggctacgccatctccacgcccacctccgagcagtatcgc
ggcgatggcatcgcggcacgaggccccgggtatggcatcatgtcaatccgcgtggatggt
aatgatgtgtttgctgtgtacaatgccacaaaggaggcccgacggcgcgctgtggcagag
aaccagcccttcctcatcgaggccatgacctacaggatcgggcaccacagcaccagtgac
gacagttcagcgtaccgctcggtggacgaggtcaattactgggacaagcaggaccacccc
atctcccggctgcggcactacctgctgagccaaggctggtgggatgaggagcaagagaag
gcctggaggaagcagtcccgcaagaaggtgatggaggcctttgagcaggcagagcggaag
cccaaacccaaccccaacctgctcttctcagacgtgtatcaggagatgcccgcccagctc
cgcaagcagcaggagtccctggcccgccacctgcagacctacggggagcactacccactg
gagcactttgataagtga
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