Macaca thibetana thibetana (Pere David's macaque): 126953682
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Entry
126953682 CDS
T08579
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb00270
Cysteine and methionine metabolism
mthb00480
Glutathione metabolism
mthb01100
Metabolic pathways
mthb01240
Biosynthesis of cofactors
mthb04216
Ferroptosis
Module
mthb_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
126953682
09106 Metabolism of other amino acids
00480 Glutathione metabolism
126953682
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
126953682
Enzymes [BR:
mthb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
126953682
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
126953682
NCBI-ProteinID:
XP_050645217
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Position
4:complement(54187095..54234833)
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EANMRKRRKEATSVLEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEASRASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKAAQKRDAVL
QGMFYFRKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LILKCNQIANELCECPELLGSAFRKVKYGGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggaaaccaagcgccatgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgttctcaagtggggcgatgaggtggaatacatgttggtatcttttgatcat
gaaaataaaaaagtccgattggtcctgtctggggagaaagttcttgaaactctacaagag
aagggggaaaggacaaacccaaaccatcctaccctttggagaccagagtatgggagttac
atgattgaagggacaccaggacagccctacggaggaaccatgtccgagttcaacacagtt
gaggccaacatgcgaaaacgccggaaggaggctacttctgtattagaagaaaatcaggct
ctttgcacaataacttcatttcccagattaggctgtcctgggttcacactgcccgaggtc
aaacccaacccagtggaaggaggagcttccaagtccctcttctttccagatgaagcaata
aacaagcaccctcgcttcagtaccttaacaagaaacatccgacataggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatagaaaca
tttcctgaggatgatgaagcttcaagggcttctaagccagatcatatttacatggatgcc
atgggatttggaatgggcaattgctgtcttcaggtgacattccaagcctgcagtatatct
gaggccagatacctttatgatcagttggctactatctgtccaattgtcatggctttgagt
gctgcatctcccttttaccgaggctatgtgtcagacatcgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccattgaagaacaat
aactataggatcagtaaatcccgatatgactcaatagacagctatttatctaagtgtggt
gagaaatataatgacatcgacttgacgatagataaagagatctacgaacagctgttgcag
gaaggcattgatcatctcctggcccagcatgttgctcatctctttattagagacccactg
acactttttgaagagaaaatacacctggatgatgctaatgagtctgaccattttgagaat
attcagtccacaaattggcagacaatgagatttaagccccctcctccaaactcagacatc
ggatggagagtagaatttcgacccatggaggtacaattaacagactttgagaactctgcc
tatgtggtgttcgtggtactgctcaccagagtgatcctttcgtacaaattggattttctc
attccactgtcaaaggttgatgagaacatgaaggcagcacagaaacgagatgctgtcttg
cagggaatgttttatttcaggaaagatatttgcaaaggtggcaacgcagtggtggatggt
tgtggcaaggcccagaacagcacagagcttgctgcagaggagtacaccctcatgagcata
gacaccatcatcaatgggaaggaaggcgtgtttcctggactgatcccaattctgaactct
taccttgaaaacatggaagtagatgtggacactagatgtagtattctgaactacctaaag
ctaattaagaagagagcatctggagaactaatgacagttgccagatggatgagggagttt
atcgcaaaccatcctgactacaagcaagacagtgtcataactgatgaaatgaattatagc
cttattttgaagtgtaaccaaattgcaaatgaattatgtgaatgcccagagttacttgga
tcagcatttaggaaagtaaaatatggtggaagtaaaactgactcatccaactag
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