| Entry |
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| Name |
(RefSeq) E3 ubiquitin-protein ligase parkin isoform X1
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| KO |
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| Organism |
mthb Macaca thibetana thibetana (Pere David's macaque)
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| Pathway |
| mthb04141 | Protein processing in endoplasmic reticulum |
| mthb05022 | Pathways of neurodegeneration - multiple diseases |
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| Brite |
KEGG Orthology (KO) [BR:mthb00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
126953705
04120 Ubiquitin mediated proteolysis
126953705
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
126953705
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
126953705
05014 Amyotrophic lateral sclerosis
126953705
05022 Pathways of neurodegeneration - multiple diseases
126953705
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:mthb04131]
126953705
04121 Ubiquitin system [BR:mthb04121]
126953705
03029 Mitochondrial biogenesis [BR:mthb03029]
126953705
Enzymes [BR:mthb01000]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.31 RBR-type E3 ubiquitin transferase
126953705
Membrane trafficking [BR:mthb04131]
Autophagy
Mitophagy
PINK1-Parkin associated proteins
126953705
Aggrephagy
Other aggrephagy associated proteins
126953705
Xenophagy
Other xenophagy associated proteins
126953705
Ubiquitin system [BR:mthb04121]
Ubiquitin ligases (E3)
Single Ring-finger type E3
RBR proteins
126953705
Mitochondrial biogenesis [BR:mthb03029]
Mitochondrial quality control factors
Mitophagy factors
Parkin-dependent mechanism factors
126953705
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
4:complement(159441106..160824171)
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| AA seq |
465 aa
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPTDQLRVIFAGKELRNDWTVQNCD
LDQQSIVHIVQRPRRKGQEMNATGGDNARNTVGGCEREPQSLTRVDLSSSVLPGDSVGLA
VILHTDSRNDSPPAGSPADRPIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGP
SCWDDVLIPNRMSGECQSPHCPGTTAEFFFKCGAHPTSDKETSVALHLIATNSRNITCIT
CTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKE
LHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPESDQRKVTCEGGNGLGC
GFAFCRECKEAYHEGECSALFEASGTTTQAYRVDERAAEQARWEEASKETIKKTTKPCPR
CHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV |
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| NT seq |
1398 nt +upstreamnt +downstreamnt
atgatagtgtttgtcaggttcaactccagccatggtttcccagtggaggtcgattctgac
accagcatcttccagctcaaggaggtggttgctaagcgacagggggttccgactgaccag
ttgcgtgtgattttcgcagggaaggagctgaggaatgactggactgtgcagaactgtgac
ctggatcagcagagcatcgttcacattgttcagagaccacggagaaaaggtcaagaaatg
aatgcaactggaggcgacaacgccagaaacacggtgggaggctgtgagcgggagccccag
agcttgactcgggtggacctcagcagctcagtcctcccaggagactctgtgggactggct
gtcattctgcacactgacagcaggaatgactcaccaccagctggcagtccagcagataga
ccaatctacaacagcttttatgtgtattgcaaaggcccctgtcaaagagtgcagccggga
aaactcagggtacagtgcagcacctgcagacaagcaacgctcaccttgacccagggtcca
tcgtgctgggatgatgttttaattccaaaccggatgagcggtgaatgccaatccccacac
tgccctgggactactgcagaatttttctttaaatgtggagcacaccccacctctgacaag
gaaacatcagtagctttgcacctgatcgcaacaaatagtcggaacatcacttgcattaca
tgcaccgacgtcaggagccccgtcctggttttccagtgcaactcccgccacgtgatttgc
ttagactgtttccacttatactgtgtgacaagactcaatgatcggcagtttgttcatgac
cctcaactgggctactccctgccttgtgtggctggctgtcccaactccttgattaaagag
ctccatcacttcaggattctgggagaagagcagtacaaccgataccagcagtatggtgca
gaggagtgtgtcctgcagatggggggcgtgttatgcccccgccctggctgtggagcgggg
ctgctgccggagtctgaccagaggaaagtcacctgtgaaggcggcaacggcctgggctgt
gggtttgccttctgccgggagtgtaaagaagcgtaccatgaaggggagtgcagtgcccta
tttgaagcctcaggaacaactactcaggcctacagagttgatgaaagagccgcagagcag
gctcgttgggaagaagcctccaaagaaaccatcaagaaaaccacgaagccctgtccccgc
tgccatgtaccagtggaaaaaaatggaggctgcatgcacatgaagtgtccgcagccccag
tgcaggctcgagtggtgctggaactgtggctgcgagtggaaccgcgtctgcatgggggac
cactggttcgacgtgtag |
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