Macaca thibetana thibetana (Pere David's macaque): 126953763
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Entry
126953763 CDS
T08579
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
mthb
Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb00230
Purine metabolism
mthb01100
Metabolic pathways
mthb04024
cAMP signaling pathway
mthb05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mthb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
126953763
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
126953763
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
126953763
Enzymes [BR:
mthb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
126953763
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
126953763
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GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
126953763
NCBI-ProteinID:
XP_050645339
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All DBs
Position
4:complement(163432306..164101366)
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AA seq
1058 aa
AA seq
DB search
MTSPEEPLAPRPQGPPPAAGDEPGCGPGKLRLEPRRSAAGGGRAAGPGLAPEWPGRGRAE
RAAPPRPPPSSAGRASPAGGPGALSARGGGCGWVAARAPLALAFSSRVPSSSPSSFYFWP
PPPPPPPSFLPSSSAFHLPVRLPGREGAAAAAAAAGGGGDAGGGGGGRQEAAPLSVPTSS
SHRGGGGSGSGGGRRRLFLSPALQGLLLPARAGPRPPPPPRLPLGQAARRAGSPGFPGAG
PGGGGRTPRRPQGAGFALAAAAALLFGSDMEDGPSNNASCFRRLTECFLSPSLTDEKVKA
YLSLHPQVLDEFVSESVSAETVEKWLKRKNNKSEDESAPKEVSRYQDTNMQGVVYELNSY
IEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCIFTPPGIKEGKPRLIP
AGPITQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLI
GILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYF
DNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKE
IRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGV
VQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSIC
TAEEWQGLMRFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRF
IMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHALFTDLERKGLLIACLCHDLDHRGFS
NTYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAII
ATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTAND
IYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPL
LKACRDNLNQWEKVIRGEETATWISSPSVAQKAAASED
NT seq
3177 nt
NT seq
+upstream
nt +downstream
nt
atgaccagccccgaggagcctcttgctccccgcccccagggtcccccgccagcagcaggg
gacgagccgggctgcggccccggcaaactccgcctggaaccccggcgcagcgcggccggc
ggggggagagcggcgggcccgggcctggcccccgagtggcctggccgcggccgggccgag
cgcgccgcgcccccgcgcccgcccccctcctccgcaggccgcgccagcccagctgggggc
cccggcgccctctctgcgcgcggcggcggctgcggctgggtcgcggcccgcgctcccttg
gcgctcgccttctcctcccgggtcccctcctcctctccatcttccttttacttctggccg
ccgccccccccgccccctccctcttttctcccctcctcatctgcctttcacctccccgtg
cgtctcccaggaagggagggcgcagcggcggcggcggcggcggcgggaggaggcggcgat
gctggcggaggaggaggaggacgacaagaggcagctcccttgagcgtccccaccagcagt
agtcaccgcggcggcggtggcagcggcagcggcggcgggcggcggcggctcttcctctcg
cctgcgctccagggcttgcttctcccagcccgtgcagggccccggccgccgccgccgccc
cggctcccactcggccaggccgcccgccgcgcgggctcccccggcttccccggcgccggc
ccaggcggcggcggccgaactccgcggcgtccccagggcgccggcttcgccctcgccgcc
gcggccgcgctgctcttcggctccgacatggaagatggaccttctaataatgcgagctgc
ttccgaaggctgactgagtgcttcctgagccccagtttgacagatgaaaaagtgaaggca
tatctttctcttcacccccaggtattagatgaatttgtatctgaaagtgttagtgcagag
acagtagagaaatggctgaagaggaagaacaacaaatcagaagatgaatcggctcctaag
gaagtcagcaggtaccaagatacgaatatgcagggagttgtatatgaactaaacagctat
atagaacaacggttggacacaggaggagacaaccagctactcctctatgaactgagcagc
atcatcaaaatagccacaaaagctgatggatttgcattgtatttccttggagagtgcaat
aatagcctgtgcatattcacaccacctgggataaaggaaggaaaaccccgcctcatccct
gctgggcccatcactcagggcaccaccatctctgcttatgtggccaagtccaggaagaca
ttgctagtagaagacatccttggagatgagcgatttccaagaggtactggactggaatca
gggactcgtatccagtctgttctttgcttaccaattgtcactgcaattggtgacttgatt
ggtattcttgagctgtatcggcactggggcaaagaagccttctgtcttagtcaccaggag
gttgcaacagcaaatcttgcctgggcttcagtagcaatacatcaggtgcaggtatgcaga
ggccttgccaaacagactgaattgaatgactttctactcgacgtatcaaaaacatatttt
gataacatagttgcaatagattctctacttgaacacataatgatatatgcaaaaaacctg
gtgaatgccgaccgttgtgcacttttccaggtagaccataagaacaaggagttatattca
gacctttttgatattggagaggaaaaggaaggaaaacccgtcttcaagaagaccaaagag
ataagattttcaattgagaaaggaattgctggccaagtagcaagaacaggggaagtcctg
aacattccagatgcctatgcagacccacgctttaacagagaagtagacttgtacacaggc
tacaccacgcggaacatcctgtgcatgcccatcgtcagccgaggcagcgtgataggtgtg
gtgcagatggtcaacaaaatcagtggcagtgccttctctaaaaccgatgaaaacaacttc
aaaatgtttgccgtcttttgtgctttagccttacactgtgctaatatgtatcatagaatt
cgccactcagagtgcatttaccgggtaacaatggaaaagctgtcctaccatagcatttgt
actgcagaagagtggcaaggcctcatgcgatttacccttcctgtgcgtctctgcaaagaa
attgaattattccactttgacattggtccttttgaaaacatgtggcctggaatttttgtc
tacatggttcatcggtcctgtgggacatcctgctttgagctcgaaaagttgtgtcgtttt
attatgtctgtgaagaagaactatcggcgggttccttatcacaactggaagcatgcggtc
actgtagcacactgcatgtacgccatacttcagaacaaccacgcgcttttcacagacctt
gagcgcaaaggactgctgatcgcgtgtctgtgtcatgacctagaccacagaggcttcagt
aacacctacctgcagaagttcgaccaccctctagcagctctctactccacttccaccatg
gagcagcaccacttctcccagaccgtgtccatcctccagctggaagggcacaatatcttc
tccactctgagctccagtgaatacgagcaggtgcttgagatcatccgcaaagccatcatt
gccacagaccttgctttatactttggaaacaggaaacagttggaagagatgtaccagacc
ggatcgctaaaccttaataatcaatcacatagagaccgtgtaattggtttgatgatgact
gcctgtgacctttgttctgtgacaaaactgtggcccgttacaaaattgacggcaaatgat
atatatgcagaattctgggctgagggtgatgaaatgaagaaattgggaatacagcctatt
cctatgatggacagagacaagaaggatgaagtcccccaaggccagcttgggttctacaat
gccgtagccattccctgctatacaacccttacccagatcctccctcccacggagcctctc
cttaaagcatgcagggataatctcaatcagtgggagaaggtgattcgaggggaggagact
gcaacctggatttcatccccgtccgtggctcagaaggcagctgcatctgaagattga
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