| Entry |
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| Name |
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
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| KO |
| K08268 | hypoxia-inducible factor 1 alpha |
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| Organism |
mthb Macaca thibetana thibetana (Pere David's macaque)
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| Pathway |
| mthb05167 | Kaposi sarcoma-associated herpesvirus infection |
| mthb05208 | Chemical carcinogenesis - reactive oxygen species |
| mthb05230 | Central carbon metabolism in cancer |
| mthb05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer |
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| Brite |
KEGG Orthology (KO) [BR:mthb00001]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
126958962
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
126958962
04137 Mitophagy - animal
126958962
04148 Efferocytosis
126958962
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
126958962
09152 Endocrine system
04919 Thyroid hormone signaling pathway
126958962
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
126958962
05205 Proteoglycans in cancer
126958962
05208 Chemical carcinogenesis - reactive oxygen species
126958962
05230 Central carbon metabolism in cancer
126958962
05231 Choline metabolism in cancer
126958962
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
126958962
09162 Cancer: specific types
05211 Renal cell carcinoma
126958962
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
126958962
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:mthb03000]
126958962
Transcription factors [BR:mthb03000]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
126958962
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
7:complement(46001868..46055253)
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| AA seq |
827 aa
MEGAGGANDKKNRISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASV
MRLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKY
MGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVKKGKEQNTQRSFFLRMKCTLTSRG
RTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDS
KTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQ
VTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTEC
VLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTE
TDDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPTSETPKPLRSSADPALNQEVALKLE
PNPESLELSFTMPQIQDQPPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKL
FAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTV
TVFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSSTHIHKETTSATSSPY
RDTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRTTVPEEELNPKILALQNAQRK
RKMEHDGSLFQAVGIGTLLQQPDDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLA
CRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN |
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| NT seq |
2484 nt +upstreamnt +downstreamnt
atggagggcgccggcggcgcgaacgacaagaaaaataggataagttctgaacgtcgaaaa
gaaaagtctcgagatgcagccagatctcggcgaagtaaagaatctgaagttttttatgag
cttgctcatcagttgccacttccacataatgtgagctcgcatcttgataaggcctctgtt
atgaggcttaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttggat
attgaagatgaaatgaaagcacaaatgaattgcttttatttgaaagccttggatggtttt
gttatggttctcacagatgatggtgacatgatttacatttctgataatgtgaacaaatac
atgggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgt
gaccatgaggaaatgagagaaatgcttacacacagaaatggccctgtgaaaaagggtaaa
gaacaaaacacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgagga
agaactatgaacataaagtctgcaacatggaaggtattgcactgcacaggccatattcac
gtatatgataccaacagtaaccaacctcagtgtgggtataagaaaccacctatgacctgc
ttggtgctgatttgtgaacccattcctcacccatcaaatattgaaattcctctagatagc
aagacttttctcagtcgacacagcctggatatgaaattttcttattgtgacgaaagaatt
accgaattgatgggatatgagccagaagaacttttaggccgctcaatttatgaatattat
catgctttggactctgatcatctgaccaaaactcatcatgatatgtttactaaaggacaa
gtcaccacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaact
caagcaactgttatatataacaccaagaactctcaaccacagtgcattgtatgtgtgaat
tatgttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgt
gtccttaaaccagttgaatcttcagatatgaaaatgactcagctattcaccaaagttgaa
tcagaagatacaagtagcctctttgacaaacttaagaaggaacctgatgctttaactttg
ctggccccagccgctggagacacaatcatatctttagattttggcagcaacgacacagaa
actgatgaccagcaacttgaggaagtaccattgtataatgatgtaatgctcccctcatcc
aacgaaaaattacagaatataaatttggcaatgtctccattacccacctctgaaacgcca
aagccacttcgaagtagtgctgaccctgcactcaatcaagaagttgcattaaaattagaa
ccaaatccagagtcattggaactttcttttaccatgccccaaattcaggatcagccacct
agtccttctgatggaagcactagacaaagttcacctgagcctaatagtcccagtgaatat
tgtttttatgtggatagtgatatggtcaatgaattcaagttggaattggtagaaaaactt
tttgctgaagacacagaagcaaagaacccattttccactcaggacacagatttagacttg
gagatgttagctccctatatcccaatggatgatgacttccagttacgttccttcgatcag
ttgtcaccattagaaagcagttccgcaagccctgaaagcgcaagtcctcaaagcacagtt
acagtattccagcagactcaaatacaagaacctactgctaatgccaccactaccactgcc
accactgatgaattaaaaacagtgacaaaagaccgtatggaagacattaaaatattgatt
gcatctccatcttctacccacatacataaagaaactactagtgccacatcatcaccatat
agagatactcaaagtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacag
acagaaaaatctcatccaagaagccctaacgtgttatctgtcactttgagtcaaagaact
acagttcctgaggaagaactaaatccaaagatactagctttgcagaatgctcagagaaag
cgaaaaatggaacatgatggttcactttttcaagcagtaggaattggaacattattacag
cagccagacgatcatgcagctactacatcactttcttggaaacgtgtaaaaggatgcaaa
tctagtgaacagaatggaatggagcaaaagacaattattttaataccctctgatttagca
tgtagactgctggggcaatcaatggatgaaagtggattaccacagctgaccagttatgat
tgtgaagttaatgctcctatacaaggcagcagaaacctactgcagggtgaagaattactc
agagctttggatcaagttaactga |
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