KEGG   Macaca thibetana thibetana (Pere David's macaque): 126964210
Entry
126964210         CDS       T08579                                 
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
mthb  Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb01521  EGFR tyrosine kinase inhibitor resistance
mthb01522  Endocrine resistance
mthb04012  ErbB signaling pathway
mthb04015  Rap1 signaling pathway
mthb04062  Chemokine signaling pathway
mthb04081  Hormone signaling
mthb04137  Mitophagy - animal
mthb04144  Endocytosis
mthb04360  Axon guidance
mthb04370  VEGF signaling pathway
mthb04510  Focal adhesion
mthb04520  Adherens junction
mthb04530  Tight junction
mthb04540  Gap junction
mthb04611  Platelet activation
mthb04613  Neutrophil extracellular trap formation
mthb04625  C-type lectin receptor signaling pathway
mthb04727  GABAergic synapse
mthb04750  Inflammatory mediator regulation of TRP channels
mthb04810  Regulation of actin cytoskeleton
mthb04912  GnRH signaling pathway
mthb04915  Estrogen signaling pathway
mthb04917  Prolactin signaling pathway
mthb04919  Thyroid hormone signaling pathway
mthb04921  Oxytocin signaling pathway
mthb04926  Relaxin signaling pathway
mthb05100  Bacterial invasion of epithelial cells
mthb05135  Yersinia infection
mthb05152  Tuberculosis
mthb05161  Hepatitis B
mthb05163  Human cytomegalovirus infection
mthb05167  Kaposi sarcoma-associated herpesvirus infection
mthb05168  Herpes simplex virus 1 infection
mthb05203  Viral carcinogenesis
mthb05205  Proteoglycans in cancer
mthb05207  Chemical carcinogenesis - receptor activation
mthb05208  Chemical carcinogenesis - reactive oxygen species
mthb05219  Bladder cancer
mthb05417  Lipid and atherosclerosis
mthb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mthb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    126964210
   04015 Rap1 signaling pathway
    126964210
   04370 VEGF signaling pathway
    126964210
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    126964210
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    126964210
   04137 Mitophagy - animal
    126964210
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    126964210
   04520 Adherens junction
    126964210
   04530 Tight junction
    126964210
   04540 Gap junction
    126964210
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    126964210
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    126964210
   04613 Neutrophil extracellular trap formation
    126964210
   04625 C-type lectin receptor signaling pathway
    126964210
   04062 Chemokine signaling pathway
    126964210
  09152 Endocrine system
   04912 GnRH signaling pathway
    126964210
   04915 Estrogen signaling pathway
    126964210
   04917 Prolactin signaling pathway
    126964210
   04921 Oxytocin signaling pathway
    126964210
   04926 Relaxin signaling pathway
    126964210
   04919 Thyroid hormone signaling pathway
    126964210
  09156 Nervous system
   04727 GABAergic synapse
    126964210
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    126964210
  09158 Development and regeneration
   04360 Axon guidance
    126964210
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    126964210
   05207 Chemical carcinogenesis - receptor activation
    126964210
   05208 Chemical carcinogenesis - reactive oxygen species
    126964210
   05203 Viral carcinogenesis
    126964210
  09162 Cancer: specific types
   05219 Bladder cancer
    126964210
  09172 Infectious disease: viral
   05161 Hepatitis B
    126964210
   05168 Herpes simplex virus 1 infection
    126964210
   05163 Human cytomegalovirus infection
    126964210
   05167 Kaposi sarcoma-associated herpesvirus infection
    126964210
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    126964210
   05152 Tuberculosis
    126964210
   05100 Bacterial invasion of epithelial cells
    126964210
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    126964210
   05418 Fluid shear stress and atherosclerosis
    126964210
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    126964210
   01522 Endocrine resistance
    126964210
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mthb01001]
    126964210
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mthb04131]
    126964210
Enzymes [BR:mthb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     126964210
Protein kinases [BR:mthb01001]
 Non-receptor tyrosine kinases
  SRC family
   126964210
Membrane trafficking [BR:mthb04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    126964210
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    126964210
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    126964210
  Macropinocytosis
   Kinases
    126964210
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 126964210
NCBI-ProteinID: XP_050663075
LinkDB
Position
10:complement(62487024..62562255)
AA seq 553 aa
MGSNKSKPKDASQRRRSLEPAENAHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq 1662 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccagcggcgccgcagcctggagccc
gccgagaacgcgcatggcgctggcgggggcgctttccccgcctcccagacccccagcaag
ccagcctcggccgacggccaccgcggccccagcgcggccttcgcccccgcggccgccgag
cccaagctgttcggaggcttcaactcctcggacaccgtcacctccccgcagagggcgggc
ccgctggccggtggagtgaccacctttgtggccctctatgactatgagtctaggacggag
acagacctgtccttcaagaaaggcgagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggagactggtggctg
gcccactcgctcagcacgggacagacaggctacattcccagcaactacgtggcgccctcc
gactccatccaggccgaggagtggtattttggcaagatcaccagacgggagtcagagcgg
ttactgctcaatgcggagaacccgagagggaccttcctcgtgcgagaaagtgagaccaca
aaaggtgcctactgcctctcagtgtccgacttcgacaacgccaagggcctcaacgtgaag
cactacaagatccgcaagctggacagcggcggcttctacatcacctcccgcacccagttc
aacagcctgcagcagctggtggcctactactccaaacacgccgacggcctgtgccaccgc
ctcaccactgtgtgccccacatccaagcctcagactcagggcctggccaaggatgcctgg
gagatccctcgggagtcgctgcggctggaggtcaagctgggccagggctgctttggcgag
gtgtggatggggacctggaacggcactaccagggtggccatcaaaaccctgaagcctggc
acgatgtctccagaggccttcctgcaggaggcccaggtcatgaagaagctgaggcatgag
aagctggtgcagttgtatgctgtggtttcggaggagcccatttacatcgtcacagagtac
atgagcaaggggagtttgctggactttctcaagggggagacgggcaagtacctgcggcta
cctcagctggtggacatggctgctcagatcgcctcaggcatggcatacgtggagcggatg
aactatgtccaccgggatcttcgtgcagccaacatcctggtgggagagaacctggtgtgc
aaagtggctgacttcgggctggctcggctcatcgaagacaatgagtacacggcccggcaa
ggtgccaaattccccatcaagtggacagctccggaagctgccctgtatggccgcttcacc
atcaagtcggacgtgtggtcctttgggatcctgctgactgagctcaccacaaagggacgg
gtgccctaccctgggatggtgaaccgcgaggtgctggaccaggtggaacggggctaccgg
atgccctgcccaccggagtgtcccgagtccctgcacgacctcatgtgccagtgctggcgg
aaggagcctgaggagcggcccaccttcgagtacctgcaggccttcctggaggactacttc
acgtccaccgagccccagtaccagcccggggagaacctctag

DBGET integrated database retrieval system