Microbulbifer thermotolerans: A3224_05210
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Entry
A3224_05210 CDS
T04393
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mthd
Microbulbifer thermotolerans
Pathway
mthd00300
Lysine biosynthesis
mthd00550
Peptidoglycan biosynthesis
mthd01100
Metabolic pathways
mthd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mthd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A3224_05210
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A3224_05210
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A3224_05210
Enzymes [BR:
mthd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A3224_05210
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AMX02059
UniProt:
A0A143HK13
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Position
1241201..1242580
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AA seq
459 aa
AA seq
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MISAISLQQLQTRFGGELINGSVQFEQVCTDTRQLDSNALFVALKGERFDAHDFVGELEG
QVLGLVVDREIPGSKLPQWRVADTTEALGQIGRMCREQFKGRVIAVTGSCGKTTVKEMLA
AIFSQRHNPCVTRGNLNNQFGLPMTLFELTSDHDVLILEMGASGPDEIAYLCGIAKPQVS
AVNNVMPAHVEGFGSVDAIARAKGKIYTGLETGGTAVVNADDDYANYWLERMPEGVHTLE
VGLGHQWPIHADNIALDDNGCPTFDLCIEGLAYRVRLQLLGEHNVHNALVAAGCAFAAGV
PAAEIASGLQSLGGVAGRMQELCGIKGAAIIDDTYNANPGSVAAAIELLAQRRGKRVLVL
GDMAELGADAEEMHRQMGELARERGLDALFTLGPLGAAASVAFSAGRHLPLHSYRDRQPL
IAALTHELNKNTTVLVKGSRSARMELVVQALCGNAKEDK
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgatcagcgccatctccctgcagcaacttcaaacgcgtttcggcggtgagctcatcaat
ggttcggtgcagtttgaacaggtgtgcaccgacacgcgccagctggattccaacgccctc
tttgtcgccttgaagggggagcgtttcgatgcgcacgactttgtcggcgaactcgaaggg
caggtattggggctggtagtggatcgggaaattcccggcagcaagctgccacagtggcgg
gtggccgataccactgaggccctcgggcagataggccgcatgtgccgggaacagtttaaa
ggccgggtgatcgcggtgactggctcctgcgggaaaactacggtcaaggaaatgctcgcg
gcgatattttcccagcggcataacccctgtgtgacccgtggcaatttgaacaatcagttc
ggcctgcccatgaccctgttcgagctgacttcagatcatgatgttttgattctggagatg
ggcgccagtggtccggatgagatcgcttatctgtgcggcattgcgaaaccccaggtgagt
gcggtcaacaacgtcatgccggcccatgtggaaggcttcggttctgtggacgccatagct
agggccaaggggaagatctacaccggtctcgaaaccggcggcacagctgtggtcaatgcc
gatgacgactacgcgaactattggctggagcggatgccggagggggtgcacacgctggaa
gtgggattggggcatcagtggcccatccacgcggacaatattgcacttgatgataatggg
tgccccaccttcgatttgtgcatcgaaggcttggcgtaccgcgtgcggttgcaattgctt
ggcgaacacaatgtgcacaatgcgctggtggccgccggctgcgcctttgccgccggtgtc
cctgcggcggaaatcgccagtggcctgcaaagcctgggtggcgtcgccggtcgtatgcag
gagctctgcggcatcaagggcgcggcgattattgacgacacatacaacgccaaccccggc
tcggtggctgcagcgattgagttgttggcacagcgccgcggcaagcgcgttctagtgctc
ggcgacatggccgaactgggagcggatgcagaggaaatgcaccgtcaaatgggcgagctg
gcgcgggaacgcggcctggatgccctgtttacccttgggccgctgggtgccgccgccagt
gttgccttcagtgccgggcgtcacttgcccctgcacagttatagggacaggcagccgctt
atcgcggcgttgacccatgaattgaataaaaacaccacagtgctggtgaaaggttcccgc
agtgcccgtatggaactggtggtgcaggcactctgtgggaacgccaaagaggataaataa
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