Methanothermobacter sp. THM-1: FZP57_08655
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Entry
FZP57_08655 CDS
T06420
Name
(GenBank) NAD-dependent isocitrate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
mthm
Methanothermobacter sp. THM-1
Pathway
mthm00290
Valine, leucine and isoleucine biosynthesis
mthm00660
C5-Branched dibasic acid metabolism
mthm01100
Metabolic pathways
mthm01110
Biosynthesis of secondary metabolites
mthm01210
2-Oxocarboxylic acid metabolism
mthm01230
Biosynthesis of amino acids
Module
mthm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
mthm_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
mthm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
FZP57_08655
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
FZP57_08655
Enzymes [BR:
mthm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
FZP57_08655
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Motif
Pfam:
Iso_dh
DUF166
Motif
Other DBs
NCBI-ProteinID:
QHN07073
UniProt:
A0A6B9TFH9
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Position
1649028..1650008
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AA seq
326 aa
AA seq
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MKIAVIPGDGIGGEVMDAALTVLDALDLNPELIMADAGDDCLERTGTPLPDETLEAVGEA
DATLFGAAGESAADVIVKLRREFGLFANLRPVRSLPGVQCLYPDLDFVIVRENTEDLYVG
DEEYTSDGAVARRVITRAASERIVRFAFDYAVGDGRGGVTAVHKANVLKKTDGIFREVFY
EVASSYPQVEANDYYVDATAMYLITQPHEFDVIVTTNMFGDILSDEAAALVGGLGVAPSA
NIGEKNAIFEPVHGSAPQIAGKNIANPTAMILSTALMLKHLKKPQEAQKIQEALEETLRN
GLVTPDLGGDLGTDEMAREIARRIEG
NT seq
981 nt
NT seq
+upstream
nt +downstream
nt
atgaagatagcggttatacccggtgatggcattggcggtgaggttatggatgctgccctc
accgtgctggatgcccttgaccttaaccctgaactcatcatggcagatgcaggagacgac
tgcctcgagagaacagggacccccctgcctgatgaaacccttgaggcggtgggtgaggct
gatgcaacactgttcggagctgcaggtgaaagcgccgctgatgtaatagttaaacttcga
cgtgaattcggcctttttgcgaatttaaggcctgtaaggtctcttccaggggttcagtgc
ctttatccggacctggattttgtgattgtccgtgagaacaccgaggatctctatgttggt
gatgaggagtacacgtctgatggtgctgttgcaaggcgtgttataaccagggctgcctcc
gagaggattgtgaggtttgcctttgattacgcggtgggtgatggccgcggcggtgttacg
gccgtccataaggccaacgtcctcaagaagacagacggcatattcagggaagtcttctac
gaggtcgcctccagttacccccaggtggaggccaatgactactatgtggatgccacagcc
atgtacctcatcacacagccccatgaattcgatgtcatcgtcacaaccaacatgttcgga
gacatactctcagacgaagccgcagccctggtcggaggcctcggagtagcaccatcagca
aacataggcgaaaaaaacgccatattcgaaccagtacacggatcagcaccacaaatagcc
ggaaaaaacatagccaaccccacagcaatgatactatcaacagcactcatgctaaaacac
ctcaaaaaaccacaagaagcccagaaaatacaggaagcacttgaagaaacactccggaat
ggacttgtaaccccggaccttggtggtgatcttggaacagatgaaatggccagggaaata
gccaggagaattgaagggtga
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