Neomoorella thermoacetica DSM 521: MOTHE_c07850
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Entry
MOTHE_c07850 CDS
T06431
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mtho
Neomoorella thermoacetica DSM 521
Pathway
mtho00300
Lysine biosynthesis
mtho00550
Peptidoglycan biosynthesis
mtho01100
Metabolic pathways
mtho01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mtho00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MOTHE_c07850 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MOTHE_c07850 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MOTHE_c07850 (murF)
Enzymes [BR:
mtho01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MOTHE_c07850 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2114
Motif
Other DBs
NCBI-ProteinID:
AKX93589
UniProt:
A0A1J5NKN0
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Position
765854..767251
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AA seq
465 aa
AA seq
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MLTATVREICDAIGGYLVAGDPAVVVKGLSTDSREIQPGMAFVALKGERFDGHDFIGAAL
SGGAAAAIGTSFPGHQVVGLRPGQALIQVDDTLLALQKLAAYHRQKVLKGPLIGVTGSSG
KTTTKNLIAAVLSPVLKVLKTPGNFNNEIGLPMTLLRLAPWHQAAVVEMAMRGKGEIASL
AAIARPTIGVITNIGTTHLGLLGSIANIAAAKGELLAALPAEGLAVLNGDNEWCRRLAAT
CPCRVVFFSTRGQGEIYARDIGDRGLEGTFFTAVFPGKEVRVQLPVPGRHNVEDALAALA
VGFSLGVEPETMARSLADWPAEDLRQDLRPGPGGSLVFNDAYNANPESMEAALQALGALP
GRRVAVLGAMLELGPAEVELHRRVGRFAAARGLYRLITVGELAGEIAAGALEAGMPADQV
FACLTHEEAAGHLRGLGHGDVVLFKGSRLTGMEKVLAIWEGSEHD
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
atgttgacagctacggtcagggagatctgtgacgccatcggcggctacctggtagccggg
gatccggcagttgtggtaaagggcctcagtaccgacagccgggagatccagccgggtatg
gcctttgttgccttgaagggagaacgctttgacggccatgattttattggtgcggcccta
tccggcggcgcggcggcggccataggaaccagtttccccggccatcaggttgtcgggctg
cgccccggccaggctttgatccaggttgacgatacccttctggccctgcaaaaactggca
gcctaccaccggcagaaagttttaaagggtcccctgatcggggtaaccggttccagcggc
aaaacaacgaccaaaaacctcattgccgccgttttgagcccggtcctgaaggtcctaaaa
acgccggggaattttaataacgagatcggcctgcccatgacccttttacgcctggccccc
tggcaccaggcagccgtggtggagatggccatgcggggcaaaggagagatagcctccctg
gcggccatagcccgaccgaccattggcgtcattaccaacatcggtaccacccacctggga
ctcctcggttcgatagccaatattgccgctgccaaaggggagttgctggcagctttgccc
gcagaaggactggcggttttgaatggcgataatgagtggtgccgccggctggcggccacc
tgtccttgccgggtggtcttcttcagtacccggggccagggggagatttacgcccgggat
attggcgatagaggcctggaggggactttttttacggccgtttttcccggtaaggaagtc
cgggtgcagctaccggtcccggggcggcacaatgtggaagatgccctggcagccctggct
gtaggcttttccctgggcgtggaaccggaaactatggcccggagcctggctgactggccg
gccgaggatttgcgccaggacctgcgtccgggcccgggcggttccctggtttttaacgac
gcatataacgccaaccctgaatccatggaggccgccctccaggccctgggcgctttaccc
ggccgccgggtggccgtcctgggggccatgctagaacttggaccggcagaagtagaactg
caccggcgggtgggacgattcgccgctgcccggggcctttatcgcctgataactgtgggc
gaactggccggggagatagccgccggcgctctggaagccgggatgccggcggatcaggtc
tttgcctgccttacccacgaggaggcggccgggcacctacggggactgggccatggagat
gtagtcctttttaaaggatcgcgtcttaccggcatggaaaaggtgctggccatctgggag
ggctccgaacatgattga
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