Methanosarcina thermophila TM-1: MSTHT_0832
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Entry
MSTHT_0832 CDS
T03892
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mthr
Methanosarcina thermophila TM-1
Pathway
mthr00290
Valine, leucine and isoleucine biosynthesis
mthr00660
C5-Branched dibasic acid metabolism
mthr01100
Metabolic pathways
mthr01110
Biosynthesis of secondary metabolites
mthr01210
2-Oxocarboxylic acid metabolism
mthr01230
Biosynthesis of amino acids
Module
mthr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
mthr_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
mthr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MSTHT_0832
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MSTHT_0832
Enzymes [BR:
mthr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MSTHT_0832
4.2.1.35 (R)-2-methylmalate dehydratase
MSTHT_0832
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AKB12590
UniProt:
A0A0E3NBM1
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Position
1047580..1048875
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AA seq
431 aa
AA seq
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MTGMSANENRPMTVSEKIFSKASGSPVKAGDFVLANIDLAMTHDITGPLAVKGFYEIMKD
REEKKVWDPTKIVIVFDHQVPADSINATANHIMLREFAEEQGILNYDVYEGVCHQVLPEK
GHVLPGDLIVGSDSHTCAYGALGAFSTGIGSTDMAAVFATGKLWFRVPETFRFEVEGSLP
ERVYSKDLILHLIGDVGVEGVRYMAAEFGGSTIRSLSIPERMTMSNMAIEMGGKAGIIEA
DEVTADYLKERILYYEFDPYWKSDEGAEYVGVRHYDVSDLEPQVACPHNVDNVKPVTEVE
GTKLDQIFVGSCTNGRFEDIKIMADIMGDEPVAKGVRLIVVPASRTEYIKLLKAGYIEKL
INAGAIVEFPCCGPCMGGSFGLLGAGEVGLATSNRNFKGREGSPESFVYLSSPATAGASA
LTGEITDPRKV
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgaccggaatgtctgctaatgaaaatcgtccgatgaccgtttcggaaaagatcttttcg
aaggcctccggaagtcccgtaaaggccggagatttcgtgctggcaaatatagacctggca
atgacgcatgacattacaggtccgctggcagtcaaaggcttttacgagataatgaaagac
agagaagagaaaaaagtctgggaccctacgaaaatagtgatcgtgtttgaccaccaagtt
cctgcggattctatcaacgccacagcaaaccatattatgcttcgggaatttgctgaggaa
cagggcattttaaattatgatgtatacgaaggagtttgccatcaggttcttcctgagaaa
gggcatgtgctgccaggagatctaatagttggctcggactcgcatacgtgtgcatatggc
gcactgggggcgttttctacgggcatagggtctactgatatggcagcggtctttgctact
ggcaagctctggttcagggtacctgaaactttccgctttgaagttgaaggcagcctgcca
gaaagggtttactcaaaagaccttattcttcacctaataggcgatgtaggagtagaagga
gtcaggtatatggctgctgagtttggaggctcaacaattcgttctctttctattcctgag
cgcatgaccatgtccaatatggcaatcgagatgggaggaaaggcaggaattatcgaagca
gatgaagtgactgcagactacctcaaagagagaatcctatactatgaatttgacccatac
tggaaatccgatgagggcgcagaatatgtaggagttaggcactacgatgtatcggacctt
gagccccaggttgcctgccctcacaatgtggataacgtgaaacccgtaaccgaagttgaa
ggcacaaaacttgaccagatctttgtaggttcctgcacgaatggcaggtttgaggatatc
aaaatcatggctgatattatgggcgatgagccagtagcaaagggcgttcgcctgattgtt
gttcccgcatcacggaccgagtatataaagctcctgaaagctggatatatagaaaaactt
ataaatgcaggtgcaatcgtagaattcccctgctgcggaccctgtatgggtggctctttc
ggcttgcttggggctggagaagtgggccttgcaacctcgaatcgcaactttaaaggcaga
gaaggaagtcctgaatcctttgtgtatctatcttcccctgcaactgcaggagcgtcagct
cttaccggagaaattactgacccaaggaaggtttga
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