Mycobacterium tuberculosis RGTB423: MRGA423_00425
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Entry
MRGA423_00425 CDS
T01994
Name
(GenBank) isocitrate dehydrogenase, NADP-dependent
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
mti
Mycobacterium tuberculosis RGTB423
Pathway
mti00020
Citrate cycle (TCA cycle)
mti00480
Glutathione metabolism
mti00720
Other carbon fixation pathways
mti01100
Metabolic pathways
mti01110
Biosynthesis of secondary metabolites
mti01120
Microbial metabolism in diverse environments
mti01200
Carbon metabolism
mti01210
2-Oxocarboxylic acid metabolism
mti01230
Biosynthesis of amino acids
mti04146
Peroxisome
Brite
KEGG Orthology (KO) [BR:
mti00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MRGA423_00425
09102 Energy metabolism
00720 Other carbon fixation pathways
MRGA423_00425
09106 Metabolism of other amino acids
00480 Glutathione metabolism
MRGA423_00425
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
MRGA423_00425
Enzymes [BR:
mti01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
MRGA423_00425
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Gene cluster
GFIT
Motif
Pfam:
IDH
Motif
Other DBs
NCBI-ProteinID:
AFE11433
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Position
complement(72321..74558)
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AA seq
745 aa
AA seq
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MSAEQPTIIYTLTDEAPLLATYAFLPIVRAFAEPAGIKIEASDISVAARILAEFPDYLTE
EQRVPDNLAELGRLTQLPDTNIIKLPNISASVPQLVAAIKELQDKGYAVPDYPADPKTDQ
EKAIKERYARCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHSMGEWSMASRTHVAHMRH
GDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEVPLDDGDVIDSMFMSKKALCDFYEE
QMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIFYKDAFAKHQELFDDLGVNVNNGLS
DLYSKIESLPASQRDEIIEDLHRCHEHRPELAMVDSARGISNFHSPSDVIVDASMPAMIR
AGGKMYGADGKLKDTKAVNPESTFSRIYQEIINFCKTNGQFDPTTMGTVPNVGLMAQQAE
EYGSHDKTFEIPEDGVANIVDVATGEVLLTENVEAGDIWRMCIVKDAPIRDWVKLTVTRA
RISGMPVLFWLDPYRPHENELIKKVKTYLKDHDTEGLDIQIMSQVRSMRYTCERLVRGLD
TIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEEN
HLRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDNDKSPSRKTGELDNR
GSQFYLAMYWAQELAAQTDDQQLAEHFASLADVLTKNEDVIVRELTEVQGEPVDIGGYYA
PDSDMTTAVMRPSKTFNAALEAVQG
NT seq
2238 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccgaacagccgaccatcatttacacgctgaccgacgaggcgccgctgctggcg
acctacgcctttctgccgattgtgcgtgcctttgccgaaccggcgggcatcaagatcgag
gccagcgacatctctgtagcggcacgcatcctggcggaattccccgattacctgaccgag
gagcagcgggtaccggataacctcgccgaactgggccggctgactcagctacccgacacc
aacatcatcaagctgccgaacatcagcgcctcggtgccacagctggtagccgccatcaag
gaactgcaagacaagggttacgcggtcccagactacccggcggacccgaagactgaccag
gagaaggccatcaaagagcgctacgccagatgcctgggcagcgcggtgaacccggtactg
cgccaaggcaattcggaccgtcgggcgcccaaggcggtgaaggagtacgcgcgcaagcac
ccgcacagcatgggcgagtggtcgatggcctcacgcacccacgtagcgcacatgcggcac
ggtgacttctacgccggcgagaagtcgatgacactggaccgcgcgcgcaacgtgaggatg
gaactgctggccaagagcggcaagacgatcgtgctcaagcccgaggtgccgctggatgac
ggcgacgtcatcgacagcatgttcatgagcaagaaagcgctgtgcgacttctacgaagag
cagatgcaggatgcgttcgagaccggcgtgatgttctccttgcacgtcaaggcgaccatg
atgaaggtcagccaccccatcgtcttcggccacgcggtcaggatcttctacaaggacgcc
ttcgccaagcaccaggagctgttcgacgacttgggcgtcaacgtcaacaatggcttgtcc
gatctgtacagcaagatcgagtcgctgccggcgtcgcaacgcgacgagatcatcgaggac
ctacaccgttgccacgaacaccgccccgagctcgcgatggtcgattcggccagaggtatc
tccaacttccactcgccgagcgatgtgatcgtggacgcctcgatgcccgcgatgattcgc
gcgggcggcaagatgtatggcgccgacggaaagctcaaggacaccaaggcggtcaacccg
gagtccaccttctcgcgcatctatcaggagatcatcaacttctgcaagacaaatggccag
ttcgatccgacgacgatgggcaccgtccccaatgtgggtctgatggcccagcaggccgag
gagtacggctcgcacgacaagacgttcgagattcccgaggacggcgtcgccaacatcgtc
gatgtcgccaccggcgaggtgctgctgaccgagaacgtggaagccggcgacatctggcgc
atgtgcatcgtcaaggacgcaccgatccgtgactgggtcaagctgactgtcacccgcgcg
cgcatctccgggatgccggtgctgttctggctggacccgtaccgcccgcacgagaacgag
ctgatcaagaaggtcaagacatacctgaaagatcacgacaccgaaggtctggacatccag
atcatgtcgcaagtgcgatccatgcgctacacgtgcgagcgcctggtccgtggactggac
accatcgccgcgaccggcaacatcctgcgcgactacctcaccgacctgttcccgatcctg
gagttaggcaccagcgccaagatgctgtccgtcgttccgctgatggccggcggcggaatg
tacgagacgggggcgggcggttcggcacccaagcacgtcaaacaattggtggaggagaat
cacctgcgctgggattctctgggtgagttcctcgcgctgggcgccggtttcgaggatatc
ggcatcaagaccggtaacgagcgggccaaactcttgggtaagaccctggatgccgccatc
ggcaagctgctggacaacgacaagagtccgtcgcgcaaaaccggtgaactcgacaaccgg
ggcagccagttctacctcgccatgtactgggcacaagagctggccgcgcagaccgacgac
cagcagctggccgaacacttcgcctcgctggcagatgtgttgaccaaaaacgaagacgtc
atcgtgcgagagctcaccgaggtacaaggcgaaccggtggacatcggcggctactacgcg
ccggacagcgacatgactacggcggtgatgcggcccagcaagacgttcaatgcagcgctg
gaggctgtccaaggctga
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