Mycobacterium tuberculosis RGTB423: MRGA423_01215
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Entry
MRGA423_01215 CDS
T01994
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
mti
Mycobacterium tuberculosis RGTB423
Pathway
mti00290
Valine, leucine and isoleucine biosynthesis
mti00770
Pantothenate and CoA biosynthesis
mti01100
Metabolic pathways
mti01110
Biosynthesis of secondary metabolites
mti01210
2-Oxocarboxylic acid metabolism
mti01230
Biosynthesis of amino acids
Module
mti_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
mti_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
mti00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MRGA423_01215
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
MRGA423_01215
Enzymes [BR:
mti01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
MRGA423_01215
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
AFE11555
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Position
complement(220132..221859)
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AA seq
575 aa
AA seq
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MPQTTDEAASVSTVADIKPRSRDVTDGLEKAAARGMLRAVGMDDEDFAKPQIGVASSWNE
ITPCNLSLDRLANAVKEGVFSAGGYPLEFGTISVSDGISMGHEGMHFSLVSREVIADSVE
VVMQAERLDGSVLLAGCDKSLPGMLMAAARLDLAAVFLYAGSILPGRAKLSDGSERDVTI
IDAFEAVGACSRGLMSRADVDAIERAICPGEGACGGMYTANTMASAAEALGMSLPGSAAP
PATDRRRDGFARRSGQAVVELLRRGITARDILTKEAFENAIAVVMAFGGSTNAVLHLLAI
AHEANVALSLQDFSRIGSGVPHLADVKPFGRHVMSDVDHIGGVPVVMKALLDAGLLHGDC
LTVTGHTMAENLAAITPPDPDGKVLRALANPIHPSGGITILHGSLAPEGAVVKTAGFDSD
VFEGTARVFDGERAALDALEDGTITVGDAVVIRYEGPKGGPGMREMLAITGAIKGAGLGK
DVLLLTDGRFSGGTTGLCVGHIAPEAVDGGPIALLRNGDRIRLDVAGRVLDVLADPAEFA
SRQQDFSPPPPRYTTGVLSKYVKLVSSAAVGAVCG
NT seq
1728 nt
NT seq
+upstream
nt +downstream
nt
atgccgcaaaccaccgacgaagccgcttccgtctcgacggtcgccgacatcaagccccgc
agtcgagacgtcaccgacggcctggagaaggccgctgcccggggcatgttgagggcggtg
ggcatggacgacgaagacttcgcgaagccacagatcggggtcgcgtcgtcgtggaacgaa
atcacgccgtgcaatctctcattggaccggctggccaacgcggtcaaggagggggtgttt
tcggccggcggctatccgcttgagttcggcacgatctcggtttcggacggcatctccatg
ggtcatgaggggatgcacttctcgctggtttcccgtgaggtgatcgccgacagcgtcgaa
gtcgtgatgcaggccgaacgactcgacggttcggtgctgctggccggatgcgacaaatcg
ctgcccggaatgctgatggccgccgcacgactggatctggcggcggtgttcctctacgcg
ggctctattttgcccggccgggccaagctctccgacggtagcgaacgagacgtcaccatc
attgacgccttcgaggcggtcggagcgtgctctcgcggtttgatgagtcgcgccgacgtc
gatgccatcgagcgggcaatctgccccggcgaaggggcatgcggcggcatgtacaccgct
aacaccatggccagcgccgccgaggcgctcggcatgtcgttgccgggcagcgcggcaccg
ccggcgaccgaccgccggcgcgacgggttcgcgcgtcgcagcggtcaggccgtcgtcgag
ctgctgcgccgcggcatcaccgcccgcgacatcctcaccaaggaggcgttcgagaacgcc
atcgcggtggtaatggcgttcggcggctcgaccaacgcggtgctgcatctgctggccatc
gcccacgaggccaacgtcgcactatcgcttcaggacttcagccggatcgggtcgggggtg
ccgcatttggccgatgtcaagccgttcggccgccatgtgatgtccgacgtcgatcacatc
ggcggtgtgccggtggttatgaaggcgctgctggacgccggtctgctacacggcgactgc
ctgacggttaccggtcacaccatggccgagaatctggctgccatcaccccgccggatcca
gatggcaaggtgctacgtgcgttggcaaacccgatccacccgagcggtggcatcaccatc
ctgcacggatcgctggcacccgaaggtgcggtggtcaagaccgccggattcgattccgac
gtattcgaaggcaccgcaagagttttcgacggcgagcgcgctgcgctggacgcccttgag
gatggcaccattaccgtgggcgacgccgtggtaatccggtacgaaggacccaagggcggc
cccgggatgcgcgaaatgctcgccatcacaggcgcgatcaaaggcgcaggactcggtaaa
gatgttctactgctgaccgacggccggttctccggtggaaccaccggcctgtgcgttggc
cacatcgcaccggaggcggtcgacggcggaccgatcgcacttctgcgcaacggcgaccgg
atccggctcgacgtggccggccgcgttctcgatgtgttggccgatccggccgaattcgcg
tcccgacaacaggatttcagtcctccaccgccgcgctacactactggcgtactgtccaag
tacgtcaagctggtcagctctgccgcggtcggcgcggtctgcggctag
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