Mycobacterium tuberculosis KZN 4207: TBSG_00973
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Entry
TBSG_00973 CDS
T01690
Name
(GenBank) acetolactate synthase large subunit ilvB1
KO
K01652
acetolactate synthase I/II/III large subunit [EC:
2.2.1.6
]
Organism
mtk
Mycobacterium tuberculosis KZN 4207
Pathway
mtk00290
Valine, leucine and isoleucine biosynthesis
mtk00650
Butanoate metabolism
mtk00660
C5-Branched dibasic acid metabolism
mtk00770
Pantothenate and CoA biosynthesis
mtk01100
Metabolic pathways
mtk01110
Biosynthesis of secondary metabolites
mtk01210
2-Oxocarboxylic acid metabolism
mtk01230
Biosynthesis of amino acids
Module
mtk_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
mtk_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
mtk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
TBSG_00973
00660 C5-Branched dibasic acid metabolism
TBSG_00973
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TBSG_00973
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
TBSG_00973
Enzymes [BR:
mtk01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.6 acetolactate synthase
TBSG_00973
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Gene cluster
GFIT
Motif
Pfam:
TPP_enzyme_M
TPP_enzyme_C
TPP_enzyme_N
CO_dh
DUF5612
Motif
Other DBs
NCBI-ProteinID:
AEB03102
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Position
1050795..1052651
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AA seq
618 aa
AA seq
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MSAPTKPHSPTFKPEPHSAANEPKHPAARPKHVALQQLTGAQAVIRSLEELGVDVIFGIP
GGAVLPVYDPLFDSKKLRHVLVRHEQGAGHAASGYAHVTGRVGVCMATSGPGATNLVTPL
ADAQMDSIPVVAITGQVGRGLIGTDAFQEADISGITMPITKHNFLVRSGDDIPRVLAEAF
HIAASGRPGAVLVDIPKDVLQGQCTFSWPPRMELPGYKPNTKPHSRQVREAAKLIAAARK
PVLYVGGGVIRGEATEQLRELAELTGIPVVTTLMARGAFPDSHRQNLGMPGMHGTVAAVA
ALQRSDLLIALGTRFDDRVTGKLDSFAPEAKVIHADIDPAEIGKNRHADVPIVGDVKAVI
TELIAMLRHHHIPGTIEMADWWAYLNGVRKTYPLSYGPQSDGSLSPEYVIEKLGEIAGPD
AVFVAGVGQHQMWAAQFIRYEKPRSWLNSGGLGTMGFAIPAAMGAKIALPGTEVWAIDGD
GCFQMTNQELATCAVEGIPVKVALINNGNLGMVRQWQSLFYAERYSQTDLATHSHRIPDF
VKLAEALGCVGLRCEREEDVVDVINQARAINDCPVVIDFIVGADAQVWPMVAAGTSNDEI
QAARGIRPLFDDITEGHA
NT seq
1857 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgcaccaaccaagccacactcaccgacattcaagccagagccacacagcgcggcg
aatgagccaaagcacccggcggctcgtccgaaacatgttgcactgcagcagcttaccggt
gcacaggcggtcatccggtcgctggaggaactcggcgtcgacgtcattttcgggattccg
ggcggtgcggtgctgccggtgtatgacccgctgttcgactcgaaaaagctgcgccacgtg
ctggtccgccacgaacagggcgccgggcatgccgccagcggctacgcgcacgtcaccggc
cgggtgggcgtgtgcatggcaacgtcgggtcccggagcgaccaacctggtgaccccgctg
gccgacgcgcagatggactcgatcccggtggtcgctatcaccggtcaggtcgggcggggg
ctgatcggcaccgacgccttccaggaggccgacatctcgggcatcacgatgccgatcacc
aagcacaactttctggtccgctccggtgacgacattccgcgggtgctggccgaggccttc
cacatcgcggcctccggccgtccgggcgcggtgctggtcgacatccccaaggacgtgctg
cagggccagtgcacgttcagctggccgccgcggatggagctgcccggctacaagcccaac
accaaaccgcacagccggcaggtccgcgaggccgccaagctgatcgcggccgcgcgcaag
ccggtgctgtatgtcggcggcggcgtcatccgcggtgaggccaccgagcagctccgggag
ctggccgagctgaccggcatcccggtggtcaccacgctgatggcccgcggcgcgtttccc
gacagccaccggcaaaacctcggcatgcccggcatgcacggcacggtggccgccgtggcg
gcgctgcagcgcagcgacctgctgatcgcgctgggtacccgcttcgacgaccgggtgacc
ggcaagctcgactcgttcgcgccggaagccaaggtcatccacgccgacatcgacccggcc
gagatcggcaagaaccgccacgccgacgtgcccatcgtcggtgacgtcaaggccgtcatc
accgaactgatcgcgatgctgcgccaccaccacattcccggcaccatcgagatggccgac
tggtgggcatacctgaacggtgtgcgcaagacctatccgctgagctatgggccgcagagc
gacggcagcctgagcccggaatacgtgatcgaaaagctcggcgagatcgccgggccggac
gccgtcttcgtcgccggcgtcggccagcaccagatgtgggccgcgcagttcatcagatac
gaaaagccgcgcagctggctgaactccggcggtctgggcaccatggggtttgccatcccg
gcggccatgggcgccaagatcgccctccccggcaccgaggtctgggcgatcgacggcgac
ggttgcttccagatgaccaaccaggagctggccacctgcgcggtcgagggcataccggtc
aaggtggcgctgatcaacaacggcaacctgggcatggtgcggcagtggcagagcctgttc
tatgccgagcggtactcgcagaccgacctggccactcattcgcaccgcatccccgacttc
gtgaaactggccgaggccttggggtgtgtggggttgcggtgcgagcgggaagaggacgtc
gtcgacgtcatcaaccaggcgcgggcgatcaacgactgcccggtggtgatcgacttcatc
gtcggtgccgacgcgcaagtgtggccgatggtggccgcgggcaccagcaatgacgagatc
caggccgcccgcggcattcgccccctgttcgacgacatcaccgaaggccacgcctga
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