KEGG   Mycobacterium tuberculosis KZN 4207: TBSG_03052
Entry
TBSG_03052        CDS       T01690                                 
Name
(GenBank) bifunctional purine biosynthesis protein purH
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
mtk  Mycobacterium tuberculosis KZN 4207
Pathway
mtk00230  Purine metabolism
mtk00670  One carbon pool by folate
mtk01100  Metabolic pathways
mtk01110  Biosynthesis of secondary metabolites
Module
mtk_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:mtk00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    TBSG_03052
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    TBSG_03052
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mtk04147]
    TBSG_03052
Enzymes [BR:mtk01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     TBSG_03052
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     TBSG_03052
Exosome [BR:mtk04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   TBSG_03052
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS Phage_zn_bind_3 DUF7127
Other DBs
NCBI-ProteinID: AEB05181
LinkDB
Position
complement(3338937..3340508)
AA seq 523 aa
MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL
TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG
ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL
AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT
AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA
HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV
LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA
CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE
TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH
NT seq 1572 nt   +upstreamnt  +downstreamnt
atgagcaccgacgacggaagacggccgatccgccgtgcgctgatcagcgtgtacgacaag
accgggctggtagacctggcacagggcctgagcgcggccggcgtcgagatcatctcgact
gggtcaacggccaagaccattgccgacaccgggattccggtgacccccgtggagcagctg
accggctttcccgaggtgctcgatggccgggtcaagacactgcacccgcgagtgcatgcc
gggctgctggctgacctgcgcaagtccgagcacgccgcggccctcgagcaactcgggatc
gaggctttcgaactcgttgtagtcaacttgtatccgttcagccagaccgtcgaatccggc
gccagtgtcgacgactgcgtcgagcagattgatatcggcgggccggcgatggtgcgggcc
gccgccaaaaaccatcccagcgcggcggtggtcaccgatccgcttgggtaccatggcgtg
cttgccgcactgcgcgccggcggattcaccctcgccgagcgcaaaaggctggcgtcgtta
gcgtttcagcatatagccgagtacgacatcgccgtcgcgagctggatgcaacagacccta
gcgcccgaacatcctgttgccgcctttccgcagtggttcggccgaagctggcgccgcgtg
gcgatgctgcgctacggcgagaacccgcaccaacaggccgctctctacggcgaccccacc
gcctggccggggctggcccaggccgagcaactgcacggaaaagacatgtcctacaacaac
ttcaccgatgcggacgcagcctggcgggccgccttcgaccacgaacaaacgtgcgtggcg
atcatcaagcacgccaacccgtgcggcatcgcaatctcgtccgtttcggtcgccgacgcg
catcgcaaggctcacgaatgcgatccgctgagcgcctacggcggggtcatcgccgccaat
accgaggtcagtgtcgaaatggccgagtatgtgagcaccatcttcaccgaagtcatcgtc
gcgcctggctacgcccccggggccctcgatgtgctggcccgcaagaagaacatccgggtg
ctggtagccgccgagccactggccggtggcagcgagttgcgtccgatcagcggtggactg
ctgatacagcagagcgaccagcttgacgcgcacggtgacaacccggcgaactggaccttg
gcgaccgggtcacctgcggaccccgcgacgctgaccgacctggtcttcgcgtggcgagcc
tgccgtgcggtcaagtcgaacgcgatagtgatagctgccgacggcgccaccgtcggcgtc
gggatgggtcaggtcaaccgtgtcgacgccgcccggttggccgtcgaacgcggcggcgag
cgggttcgcggcgcggtggcagcctcggatgcgttcttcccctttcccgacggcctggaa
acgttggccgccgcgggggtcaccgcggtcgtccaccccggtggctcggtgcgcgacgag
gaagtgaccgaagcggcggccaaggccggtgtcaccctatatctcaccggggcgcggcac
ttcgcgcactga

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