Mycobacterium tuberculosis Erdman = ATCC 35801: ERDMAN_2287
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Entry
ERDMAN_2287 CDS
T02526
Symbol
cobL
Name
(GenBank) precorrin-6y methyltransferase
KO
K00595
precorrin-6B C5,15-methyltransferase / cobalt-precorrin-6B C5,C15-methyltransferase [EC:
2.1.1.132
2.1.1.289
2.1.1.196
]
Organism
mtn
Mycobacterium tuberculosis Erdman = ATCC 35801
Pathway
mtn00860
Porphyrin metabolism
mtn01100
Metabolic pathways
mtn01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mtn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
ERDMAN_2287 (cobL)
Enzymes [BR:
mtn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.132 precorrin-6B C5,15-methyltransferase (decarboxylating)
ERDMAN_2287 (cobL)
2.1.1.196 cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating]
ERDMAN_2287 (cobL)
2.1.1.289 cobalt-precorrin-7 (C5)-methyltransferase
ERDMAN_2287 (cobL)
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Gene cluster
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Motif
Pfam:
TP_methylase
Methyltransf_2
Methyltransf_23
Motif
Other DBs
NCBI-ProteinID:
BAL66080
UniProt:
A0A0H3LBH6
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Position
complement(2325048..2326220)
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AA seq
390 aa
AA seq
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MIIVVGIGADGMTGLSEHSRSELRRATVIYGSKRQLALLDDTVTAERWEWPTPMLPAVQG
LSPDGADLHVVASGDPLLHGIGSTLIRLFGHDNVTVLPHVSAVTLACARMGWNVYDTEVI
SLVTAQPHTAVRRGGRAIVLSGDRSTPQALAVLLTEHGRGDSKFSVLEQLGGPAERRRDG
TARAWACDPPLDVDELNVIAVRYLPDERTSWAPDEAFAHDGQITKHPIRVLTLAALAPRP
GQRLWDVGAGSGAIAVQWCRSWPGCTAVAFERDERRRRNIGFNAAAFGVSVDVRGDAPDA
FDDAARPSVIFLGGGVTQPGLLEACLDSLPAGGNLVANAVTVESEAALAHAYSRLGGELR
RFQHYLGEPLGGFTGWRPQLPVTQWSVTKR
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgatcatcgttgtcgggatcggcgccgacggcatgaccggtctctccgagcattctcgc
tccgaattgcgcagggccacagtaatttacggctcgaaacggcaacttgccctgctcgac
gataccgtcaccgccgagcgctgggagtggccgacgccgatgctgcccgcggtgcaaggc
ctgtcaccggatggggctgacctacacgtggttgccagcggcgacccgttgttgcatggt
atcggctccaccctgatccggctgttcggccacgacaacgtgaccgtgttgccgcacgtg
tccgcggtgacgttggcgtgcgcccggatgggctggaacgtgtatgacaccgaggtgatc
agcctggtcaccgcgcaaccacacaccgcggtgcgccgcggcggccgggccatcgtgctg
tccggcgatcggtccaccccgcaggcgctggcggtgctgctgaccgagcacggtcgcggt
gactccaagttcagcgtgctcgaacagcttggcggcccggccgaacgccgccgcgacggt
acggcccgggcatgggcctgcgacccacccctcgatgtcgatgagctcaacgtgatcgcc
gtgcgctacctgcccgacgagcgcacgtcgtgggcacccgacgaggcattcgcgcacgac
gggcagatcaccaaacacccgatccgcgtgctgaccctggctgcgctggcgccaaggccc
gggcagcggttatgggacgtcggcgcgggctcaggcgccatcgcggtccagtggtgtcgg
agctggccgggctgcaccgcggtggcgttcgagcgcgacgaacggcgccgccgcaacatt
gggttcaatgccgcggccttcggggtgagcgtcgacgtgcgcggcgacgcgcccgatgcg
ttcgacgacgccgcacggccgtcggtgatttttcttggcggtggtgtaacccagccaggc
ctgcttgaggcctgcctggacagcctgcccgcaggcgggaacttggtcgccaacgctgtc
accgtcgaatcggaagccgctctggcgcatgcatattcgcgcctcggtggcgagctacga
cgattccagcactatctcggcgaaccgctgggcggcttcaccggttggcgcccacagctg
ccggtcacccagtggtcggtgaccaagcgatga
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