Mycobacterium tuberculosis Erdman = ATCC 35801: ERDMAN_2614
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Entry
ERDMAN_2614 CDS
T02526
Symbol
mbtF
Name
(GenBank) peptide synthetase MBTF (peptide synthase)
KO
K04792
mycobactin peptide synthetase MbtF
Organism
mtn
Mycobacterium tuberculosis Erdman = ATCC 35801
Pathway
mtn01053
Biosynthesis of siderophore group nonribosomal peptides
Brite
KEGG Orthology (KO) [BR:
mtn00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01053 Biosynthesis of siderophore group nonribosomal peptides
ERDMAN_2614 (mbtF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
mtn01008
]
ERDMAN_2614 (mbtF)
Polyketide biosynthesis proteins [BR:
mtn01008
]
Nonribosomal peptide synthetase (NRPS)
Nonlinear NRPS
Mycobactin synthetase
ERDMAN_2614 (mbtF)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Condensation
AMP-binding
PP-binding
AMP-binding_C
PapA_C
Motif
Other DBs
NCBI-ProteinID:
BAL66403
UniProt:
A0A0H3LBH0
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All DBs
Position
complement(2646627..2650997)
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AA seq
1456 aa
AA seq
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MTRADARGAIDDVMALSPLQQGLFSRATLVAAESGSEAAEADPYVIAMAADAAGPLDIAL
LRDCAAAMLTRHPNLRASFLHGNLSRPVQVIPSSAEVLWRHVRAHPSEVGALAAEERRRR
FDVGRGPLIRFLLIELPDECWHLVIVAHHIVIDGWSLPLFVSELLALYRAGGHVAALPAA
PRPYRDYIGWLAGRDQTASRAMWADHLNGLDGPTLLSPALADTPVQPGIPGRTEVRLDRE
ATAELADAARTRGVTISTLVQMAWATTLSAFTGRGDVTFGVTVSGRPSELSGVETMIGLF
INTVPLRVRLDARATVGGQCAVLQRQFAMLRDHSYLGFNEFRAIAGIGEMFDTLLVYENF
PPGEVVGTAEFVANGVTFRPVALESLSHFPVTVAAHRSTGELTLLVEVLDGALGTMAPES
LGRRVLAVLQRLVSRWDRPLRDVDILLDGEHDPTAPGLPDVTTSAPAVHTRFAEIAAAQP
DSVAVSWADGQLTYRELDALADRLATGLRRADVSRETPVAVALSRGPRYVAAMLAVLKAG
GMIVPLDPAMPGERVAEILRQTSAPVVIDEGVFAASVGADILEDDRAITVPVDQAAYVIF
TSGTTGTPKGVIGTHRALSAYADDHIERVLRPAAQRLGRPLRIAHAWSFTFDAAWQPLVA
LLDGHAVHIVDDHRQRDAGALVEAIDRFGLDMIDTTPSMFAQLHNAGLLDRAPLAVLALG
GEALGAATWRMIQQNCARTAMTAFNCYGPTETTVEAVVAAVAEHARPVIGRPTCTTRAYV
MDSWLRPVPDGVAGELYLAGAQLTRGYLGRPAETAARFVAEPNGRGSRMYRTGDVVRRLP
DGGLEFLGRSDDQVKIRGFRVEPGEIAAVLNGHHAVHGCHVTARGHASGPRLTAYVAGGP
QPPPVAELRAMLLERLPRYLVPHHIVVLDELPLTPHGKIDENALAAINVTEGPATPPQTP
TELVLAEAFADVMETSNVDVTAGFLQMGLDSIVALSVVQAARRRGIALRARLMVECDTIR
ELAAAIDSDAAWQAPANDAGEPIPVLPNTHWLYEYGDPRRLAQTEVIRLPDRITRERLDA
VLAAVVDGHEVLRCRFDRDAMALVAQPKTDILSEVWVSGELVTAVAEQTLGALASLDPQA
GRLLSAVWLREPDGPGVLVLTAHVLAMDPASWRIVLGELDAGLHALAAGRAPSPARENTS
YRQWSRLLAQRAKALDSVDFWVAELEGADPPLGARRVAPQTDRVGELAITMSISDADLTA
RLLSTGRSMTDLLATAAARMVTAWRRQRGQQTPAPLLALETHGRADVHVDKTADTSDTVG
LLSAIYPLRIHCDGATDFARIPGSGIDYGLLRYLRADTAERLRAHREPQLLLNYLGSLHV
GVGDLAVDRALLADVGQLPEPEQPVRHELTVLAALLGPADAPVLATRWRTLPDILSADDV
ATLQSLWQGALAEITA
NT seq
4371 nt
NT seq
+upstream
nt +downstream
nt
gtgacgcgagccgacgcgcggggcgccatcgacgatgtgatggcgctcagcccattgcaa
cagggactgttttctagggcgacactggtcgccgcggagtccggctctgaggccgcagag
gccgacccgtatgtgatcgcgatggcggccgacgcggccggcccgctcgacatcgccttg
cttcgcgactgcgctgccgcgatgctgacccggcaccccaacctgcgggcgagcttccta
cacgggaacctgagccggcccgtgcaggtaataccatccagtgccgaggtgctttggcgt
cacgtgcgcgcccaccccagtgaggtcggggcgctggcagccgaagagcgccggcgccgc
ttcgacgtcggccgcggaccactcatccggttcctgctcatcgaactaccggacgaatgt
tggcatctggtcatcgtcgcgcaccacatcgtcatcgacggatggtcgttgccgctgttc
gtctccgagctgctcgccttgtatcgggctggtggtcacgtcgccgcgttgccggcagcg
ccgcggccgtatcgcgactacatcggctggctggccggccgcgatcagacggctagccgc
gcaatgtgggcggaccacctcaatggcctggacggcccgactctgttatcgccggcactc
gccgacactcctgtgcagccgggtattccgggacgcaccgaagtgcgccttgaccgtgaa
gccaccgcggagctggccgatgccgcccgcacccgtggcgtcacgatcagcacacttgtt
caaatggcttgggctaccacgctttcagcattcaccggtcgtggcgatgtgacgttcggt
gtgacggtgtccggcaggcccagcgaactgtccggcgtggaaacgatgatcggcctgttc
atcaatacggtgccactgcgggtccgcctggacgcccgcgctaccgtcggcgggcaatgc
gctgtcctacaacgtcaattcgccatgttgcgcgaccacagctatctcggtttcaacgag
tttcgtgccatcgccggtatcggtgagatgttcgacaccctactggtgtatgagaacttc
ccgcccggcgaggtggtgggcaccgcggagttcgtcgcaaacggggtgacgttccgtccg
gtggcgctagagagtttgtcgcactttccggtgaccgtcgccgcgcaccgcagcaccggt
gagctcacgctgctagtggaggtgctcgacggtgcgctgggcacgatggcgcccgaaagc
ctcggcaggcgggtgctggctgtgttacagcgcttggtcagccggtgggatcggccgctg
cgcgacgtcgacattctgctggacggcgagcacgatccgaccgcacccggcctgccggat
gtgacgacgtcggcacccgcggtgcatacccggttcgccgaaatcgctgcggcacagcct
gactcggtggcggtcagttgggcggatggtcagctgacgtaccgggagctggatgcattg
gccgaccggctggccactgggctgcgccgcgcggacgtgagtcgcgagaccccggtggcc
gtcgcgctgtcccgtggtccgcgctacgtggccgccatgctggcggtcctcaaggcgggt
ggcatgatcgtgccgctggacccggcgatgcccggtgagcgtgtcgccgagatcttgcgc
cagacatcggctccggtggtcatcgatgagggcgtgttcgccgcttcggttggcgctgac
atactcgaggacgaccgtgccatcacggtgccggtggaccaggcggcctacgtgattttc
acctccggcaccaccggtaccccgaaaggtgtcatcggcacccatcgggcgctgtcggcc
tacgccgacgaccacatcgagcgcgtgttgcggccggcggcccagcggctcgggcgcccg
ctgcgaatcgcgcatgcctggtcgttcaccttcgacgcggcgtggcagccgttggtcgca
ctgcttgacggccacgcggtgcacattgtcgacgaccatcgtcagcgggacgcaggggcg
ctggtcgaagcgatcgaccgattcggtctggacatgattgacaccacgccgtcgatgttc
gcccagctgcacaacgctggactgctcgaccgggcgccgttggcggtgcttgcgctcggc
ggcgaagccttgggcgccgcgacgtggcggatgatccagcagaactgcgcgcgcacggcc
atgacggccttcaactgctacgggcctaccgagaccacggtcgaagccgtggtcgccgcc
gttgctgagcatgcgcgaccggtcatcggacgtccgacctgcaccacccgcgcctacgtc
atggactcctggctgcggccggtgcccgatggcgtcgccggcgagctgtatctggcgggc
gcccagttgacccgcggttacctcggccgcccggccgagactgcggcgcgctttgtcgct
gagccaaacgggcgcggtagccgaatgtaccgcaccggagatgtggtgcgccgcctgccc
gacggtggactggagttcctcgggcgcagcgatgaccaggtgaagatccgcggtttccgc
gtcgagccgggtgagattgccgcggtgctcaacggccaccatgcggtgcacggttgccat
gtgacggcccgcggccatgccagtggcccccggctgacggcgtatgtggcaggcggacca
caaccgccaccggtggccgaattgcgggcgatgctgctagagcggttgccgcgttatcta
gtcccgcaccatatcgtcgtcctcgacgagttaccgctgactccacacggcaagatcgac
gaaaacgctttggcggcaatcaatgtcaccgaaggaccggcaactccgccgcagacaccg
accgagctggtgctggccgaggcgttcgccgatgtcatggaaacctcgaacgtcgatgtc
accgcgggctttttgcagatgggtctagacagcatcgtggcgctgtcggtggtgcaggcc
gcgcgccgtcgtgggattgcgttgcgggccaggctgatggtggagtgcgacaccatccgt
gaactcgcggcggccattgactccgatgccgcatggcaggcaccggccaacgatgccggc
gagccgatcccggtgctacccaacactcattggctctacgagtacggcgacccgcgccgg
ctggcacaaaccgaggtcatcaggttgcccgaccggatcacccgcgaacgcctggatgcc
gtgttggccgcggtcgtcgacggacacgaggtgttgcggtgccggttcgaccgggatgcg
atggcccttgtcgcacaaccgaaaacggacattctcagcgaggtttgggtcagcggtgaa
ctggtcaccgcggtggccgagcagactcttggcgcgctggcgagtctcgacccccaggcc
ggccgactgctctcggcggtgtggctgcgcgaacccgacgggcccggtgttctggtgctg
accgcccatgtgctggcgatggacccagcctcctggcggattgtgctgggtgaactcgac
gccggcctgcacgcgctggcggccgggcgcgcgcccagcccagcgcgcgagaacaccagc
taccggcagtggtcgcggctgctggcgcagcgggctaaggcgctggatagcgttgatttc
tgggtcgccgaactcgagggcgccgatccgccgttgggtgcccgcagggtggcgccgcag
accgaccgggttggtgagctagcgatcaccatgtcgatctccgacgccgatctgaccgcg
cggctgctttcgacgggacggtcgatgaccgatctgctggctaccgccgctgcgcggatg
gtgaccgcctggcgccggcaacgcggtcaacaaacaccagcaccgctgttggcgttggag
acgcatggccgcgcggacgtccacgtcgataagactgccgacaccagcgacacggtcggg
ctgctcagcgcgatctatccgctgcgcatccactgcgacggcgcgaccgacttcgcgcgg
atacccggcagcggcatcgattacggcctgctgcggtacctgcgcgccgataccgcggag
cgactacgcgcccaccgcgaaccccagctgctgctgaactatctgggtagcctgcacgtc
ggggtgggagatctggcggtcgaccgcgcactactggctgatgtggggcaactgcctgaa
cccgaacagccggtgcgccacgaactgacggtgctggcggcgctcctcgggcccgccgac
gctcccgtgctagccacgcggtggcgcacgctgcccgacatcctgtccgccgacgacgtc
gccacgctgcaatcactgtggcagggcgcgctggcggagataacagcatga
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